The Impact of Oral Collagen Supplementation on Joint Function, Muscle Recovery, and Musculoskeletal Health in Athletes: A Narrative Review
DOI:
https://doi.org/10.12775/JEHS.2024.67.55035Keywords
collagen, supplementation, athletes, sportAbstract
The purpose of this review is to evaluate the effects of oral collagen supplementation on joint function, muscle recovery, and overall musculoskeletal health in athletes. Collagen, a key protein in the body, is essential for the health of joints, muscles, and connective tissues. As collagen production declines with age, supplementation has become a promising strategy for improving athletic performance and reducing injury risk. This review analysed recent studies published from 2016 onwards, focusing on the impact of collagen supplementation, particularly in combination with regular training. The research involved a comprehensive literature search in the MEDLINE database, initially identifying 82 records, with 39 undergoing quality assessment. Ultimately, 26 studies met the inclusion criteria and were included in the final analysis. The findings indicate that collagen peptides significantly enhance joint stability, reduce pain, and accelerate recovery from injuries such as Achilles tendinopathy. Moreover, collagen supplementation combined with resistance training was shown to improve muscle strength, body composition, and recovery markers more effectively than training alone. The review also highlights collagen's role in extracellular matrix remodelling and anti-inflammatory responses, offering potential benefits in tissue repair and injury prevention. These results suggest that collagen supplementation could be a valuable addition to athletes' training regimens, warranting further research to optimize dosing strategies and explore its mechanisms of action.
References
León-López A, Morales-Peñaloza A, Martínez-Juárez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Álvarez G. Hydrolyzed Collagen—Sources and Applications. Molecules. 2019;24. http://dx.doi.org/10.3390/MOLECULES24224031
Khatri M, Naughton RJ, Clifford T, Harper LD, Corr L. The Effects of Collagen Peptide Supplementation on Body Composition, Collagen Synthesis, and Recovery from Joint Injury and Exercise: A Systematic Review. Amino Acids. 2021;53:1493-1506. http://dx.doi.org/10.1007/s00726-021-03072-x
Praet SFE, Purdam CR, Welvaert M, Vlahovich N, Lovell G, Burke LM, et al. Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients. Nutrients. 2019;11:76. http://dx.doi.org/10.3390/nu11010076
Zdzieblik D, Oesser S, Gollhofer A, König D. Improvement of Activity-Related Knee Joint Discomfort Following Supplementation of Specific Collagen Peptides. Appl Physiol Nutr Metab. 2017;42:588-595. http://dx.doi.org/10.1139/apnm-2016-0390
Kwatra B. Collagen Supplementation: Therapy for the Prevention and Treatment of Osteoporosis and Osteoarthritis: A Review. World J Pharm Pharm Sci. 2020;9:589-604. http://dx.doi.org/10.20959/WJPPS20205-16076
Kirmse M, Oertzen-Hagemann V, de Marées M, Bloch W, Platen P. Prolonged Collagen Peptide Supplementation and Resistance Exercise Training Affects Body Composition in Recreationally Active Men. Nutrients. 2019;11. http://dx.doi.org/10.3390/NU11051154
Hurley M, Dickson K, Hallett R, Grant R, Hauari H, Walsh N, et al. Exercise Interventions and Patient Beliefs for People with Hip, Knee or Hip and Knee Osteoarthritis: A Mixed Methods Review. Cochrane Database Syst Rev. 2018;4. http://dx.doi.org/10.1002/14651858.CD010842.PUB2
Zdzieblik D, Brame J, Oesser S, Gollhofer A, König D. The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. Nutrients. 2021;13:523. http://dx.doi.org/10.3390/nu13020523
Dressler P, Gehring D, Zdzieblik D, Oesser S, Gollhofer A, König D. Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability. J Sports Sci Med. 2018;17:298-304.
Jendricke P, Kohl J, Centner C, Gollhofer A, König D. Influence of Specific Collagen Peptides and Concurrent Training on Cardiometabolic Parameters and Performance Indices in Women: A Randomized Controlled Trial. Front Nutr. 2020;7. http://dx.doi.org/10.3389/fnut.2020.580918
Oertzen-Hagemann V, Kirmse M, Eggers B, Pfeiffer K, Marcus K, de Marées M, Platen P. Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men. Nutrients. 2019;11:1072. http://dx.doi.org/10.3390/nu11051072
Centner C, Jerger S, Mallard A, Herrmann A, Varfolomeeva E, Gollhofer S, et al. Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction. Front Physiol. 2022;13. http://dx.doi.org/10.3389/fphys.2022.838004
Jerger S, Jendricke P, Centner C, Bischof K, Kohl J, Keller S, et al. Effects of Specific Bioactive Collagen Peptides in Combination with Concurrent Training on Running Performance and Indicators of Endurance Capacity in Men: A Randomized Controlled Trial. Sports Med Open. 2023;9:103. http://dx.doi.org/10.1186/s40798-023-00654-9
Bischof K, Stafilidis S, Bundschuh L, Oesser S, Baca A, König D. Reduction in Systemic Muscle Stress Markers after Exercise-Induced Muscle Damage Following Concurrent Training and Supplementation with Specific Collagen Peptides—A Randomized Controlled Trial. Front Nutr. 2024;11. http://dx.doi.org/10.3389/fnut.2024.1384112
K. Bischof, S. Stafilidis, L. Bundschuh, S. Oesser, A. Baca, and D. König, “Influence of specific collagen peptides and 12-week concurrent training on recovery-related biomechanical characteristics following exercise-induced muscle damage—A randomized controlled trial,” Front. Nutr., vol. 10, Nov. 2023, doi: 10.3389/fnut.2023.1266056.
Zdzieblik D, Jendricke P, Oesser S, Gollhofer A, König D. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. Int J Environ Res Public Health. 2021;18:4837. http://dx.doi.org/10.3390/ijerph18094837
Jerger S, Centner C, Lauber B, Seynnes O, Friedrich T, Lolli D, et al. Specific Collagen Peptides Increase Adaptions of Patellar Tendon Morphology Following 14 Weeks of High-Load Resistance Training: A Randomized-Controlled Trial. Eur J Sport Sci. 2023;23:2329-2339. http://dx.doi.org/10.1080/17461391.2023.2232758
Kviatkovsky SA, Hickner RC, Cabre HE, Small SD, Ormsbee MJ. Collagen Peptides Supplementation Improves Function, Pain, and Physical and Mental Outcomes in Active Adults. J Int Soc Sports Nutr. 2023;20. http://dx.doi.org/10.1080/15502783.2023.2243252
Zdzieblik D, Oesser S, König D. Specific Bioactive Collagen Peptides in Osteopenia and Osteoporosis: Long-Term Observation in Postmenopausal Women. J Bone Metab. 2021;28:207-213. http://dx.doi.org/10.11005/jbm.2021.28.3.207
van Dam L, Terink R, Mensink M, de Vos RJ, Zwerver J. The JUMPFOOD Study: Additional Effect of Hydrolyzed Collagen and Vitamin C to Exercise Treatment for Patellar Tendinopathy (Jumper’s Knee) in Athletes—Study Protocol for a Double-Blind Randomized Controlled Trial. Trials. 2023;24:768. http://dx.doi.org/10.1186/s13063-023-07783-2
Jerger S, Centner C, Lauber B, Seynnes O, Sohnius T, Jendricke P, et al. Effects of Specific Collagen Peptide Supplementation Combined with Resistance Training on Achilles Tendon Properties. Scand J Med Sci Sports. 2022;32:1131-1141. http://dx.doi.org/10.1111/sms.14164
Sheridan HC, Parker LJF, Hammond KM. Dietary Supplements for Consideration in Elite Female Footballers. Eur J Sport Sci. 2022;22:733-744. http://dx.doi.org/10.1080/17461391.2021.1988149
Balius R, Álvarez G, Baró F, Jiménez F, Pedret C, Costa E, et al. A 3-Arm Randomized Trial for Achilles Tendinopathy: Eccentric Training, Eccentric Training Plus a Dietary Supplement Containing Mucopolysaccharides, or Passive Stretching Plus a Dietary Supplement Containing Mucopolysaccharides. Curr Ther Res. 2016;78:1-7. http://dx.doi.org/10.1016/j.curtheres.2016.11.001
Lis DM, Jordan M, Lipuma T, Smith T, Schaal K, Baar K. Collagen and Vitamin C Supplementation Increases Lower Limb Rate of Force Development. Int J Sport Nutr Exerc Metab. 2022;32:65-73. http://dx.doi.org/10.1123/ijsnem.2020-0313
Rawson ES, Miles MP, Larson-Meyer DE. Dietary Supplements for Health, Adaptation, and Recovery in Athletes. Int J Sport Nutr Exerc Metab. 2018;28:188-199. http://dx.doi.org/10.1123/ijsnem.2017-0340
Heaton LE, Davis JK, Rawson ES, Nuccio RP, Witard OC, Stein KW, et al. Selected In-Season Nutritional Strategies to Enhance Recovery for Team Sport Athletes: A Practical Overview. Sports Med. 2017;47:2201-2218. http://dx.doi.org/10.1007/s40279-017-0759-2
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Joanna Gołda, Julia Mężyk, Aleksandra Snopkowska, Piotr Gacka, Marcin Dołęga, Olgierd Dróżdż, Dominika Musialska
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 279
Number of citations: 0