The effect of NADP on some values of the renal acid-regulating function at experimental diabetes melli

Abstract

Diabetes is a significant social problem, since it leads both to disability and high mortality rate. The experiment involved 32 sexually mature nonlinear males of white rats. Experimental groups of animals were administered a single streptozotocin dose of 70 mg/kg intraperitoneally and NADP – 30 mg/kg. The animals in the experimental groups were slaughtered and studied on the 11^th, 21^st and 31^st days after streptozotocin administration. The studies have shown that NADP affects the metabolism, reduces the production of acids and, as a result, reduces the excretion of acids by the kidneys in experimental animals.