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Journal of Education, Health and Sport

Malignant peripheral nerve sheath tumor in a patient without neurofibromatosis 1 (NF1): a rare case of primary lung location
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Malignant peripheral nerve sheath tumor in a patient without neurofibromatosis 1 (NF1): a rare case of primary lung location

Authors

  • Anna Grzywa-Celińska Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin
  • Katarzyna Szmygin-Milanowska Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin
  • Justyna Emeryk-Maksymiuk Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of Lublin
  • Maria Walczyna Chair and Department of Clinical Pathomorphology, Medical University of Lublin
  • Michał Palonka Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin
  • Adam Krusiński Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin
  • Jan Siwiec Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin

Keywords

malignant peripheral nerve sheath tumor, lung, primary location

Abstract

We present a rare case of a patient operated due to a lung tumor, which was ultimately diagnosed as malignant peripherial nerve sheath tumor (MPNST). MPNSTs are rare tumors of soft tissue with mesenchymal origin. The World Health Organization has distinguished this group in order to unify terms in mesenchymal heterogeneous malignant tumors, e.g. neurofibrosarcomas, malignant schwannomas and malignant neurilemmoma [1]. They can occur as a result of neoplastic expansion of peripheral nerves’ branches, peripheral nerve fibers’ sheaths or Schwann cells, although many researchers believe that these tumors can derive not only from one, but several cell lines. MPNSTs are very rare in thorax, where they show aggressive pattern of growth [2] and stem from pleural cells rather than lung tissue. 

 

 

 

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Published

2018-01-02

How to Cite

1.
GRZYWA-CELIŃSKA, Anna, SZMYGIN-MILANOWSKA, Katarzyna, EMERYK-MAKSYMIUK, Justyna, WALCZYNA, Maria, PALONKA, Michał, KRUSIŃSKI, Adam and SIWIEC, Jan. Malignant peripheral nerve sheath tumor in a patient without neurofibromatosis 1 (NF1): a rare case of primary lung location. Journal of Education, Health and Sport. Online. 2 January 2018. Vol. 8, no. 1, pp. 11-17. [Accessed 7 July 2025].
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Issue

Vol. 8 No. 1 (2018)

Section

Case Reports

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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