Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

Correlative link ages between indices of bone metabolism and thyroid hormones in rats with periodontitis
  • Home
  • /
  • Correlative link ages between indices of bone metabolism and thyroid hormones in rats with periodontitis
  1. Home /
  2. Archives /
  3. Vol. 7 No. 12 (2017) /
  4. Research Articles

Correlative link ages between indices of bone metabolism and thyroid hormones in rats with periodontitis

Authors

  • Vitaliy Shcherba Horbachevsky Ternopil State Medical University
  • Andriy Miz Horbachevsky Ternopil State Medical University
  • Mariia Kyryliv Horbachevsky Ternopil State Medical University
  • Iryna Bekus Horbachevsky Ternopil State Medical University
  • Inna Krynytska Horbachevsky Ternopil State Medical University
  • Mykhaylo Korda Horbachevsky Ternopil State Medical University

Keywords

periodontitis, thyroid hormones, bone metabolism, correlation

Abstract

Introduction: It has been established that changes in the bone tissue of the jaw are present in all cases where there are at least small pathological inflammatory changes in the mucous membrane of the oral cavity. This suggests a significantly greater pathogenetic relationship between inflammatory changes in the mucosa and changes in the bone part of the periodontal disease. Despite a large number of studies, the molecular mechanisms of the influence of thyroid hormones on the bone metabolism have not been completely studied. 

The aim of study: to clarify mechanisms of the periodontitis development in rats with thyroid dysfunction based on a comparative analysis of the correlations between the bone metabolism indices and the concentration of  thyroid stimulating hormone,  free thyroxine and free triiodothyronine.

Material and methods: Experimental studies were conducted on male, nonliner, white rats of around 4 months of age.  The experimental animals were divided into the following groups: І – control animals;  ІІ – animals with periodontitis; ІІІ – animals with periodontitis combined with hyperthyroidism; IV – animals with periodontitis combined with hypothyroidism. Total calcium, ionized calcium, phosphorus, osteocalcin concentration and  activity of phosphatases were measured. Correlation analysis was performed between all the studied indices. Coefficient of linear correlation (r) and its fidelity (p) was calculated that was accordingly denoted in the tables (correlation matrices). The correlation coefficient was significant at p<0.05.

Results: The conducted correlative analysis shows that there are different interconnections between the indices of calcium-phosphorus metabolism, bone formation and bone resorption with free triiodothyronine, free thyroxine and thyroid stimulating hormone, in case of the experimental periodontitis combined with thyroid dysfunction. In animals with modelled periodontitis combined with hyperthyroidism, more correlative interactions with triiodothyronine, thyroxine and thyroid stimulating hormone were established compared to the rats of hypothyroid group.

Conclusions: Consequently, the thyroid dysfunction significantly affects the parameters of bone metabolism in case of an experimental periodontitis, which requires further research.

Downloads

  • PDF

Published

2017-12-15

How to Cite

1.
SHCHERBA, Vitaliy, MIZ, Andriy, KYRYLIV, Mariia, BEKUS, Iryna, KRYNYTSKA, Inna and KORDA, Mykhaylo. Correlative link ages between indices of bone metabolism and thyroid hormones in rats with periodontitis. Journal of Education, Health and Sport. Online. 15 December 2017. Vol. 7, no. 12, pp. 184-196. [Accessed 28 June 2025].
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 7 No. 12 (2017)

Section

Research Articles

License

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 219
Number of citations: 0

Search

Search

Browse

  • Browse Author Index
  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

periodontitis, thyroid hormones, bone metabolism, correlation
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop