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Journal of Education, Health and Sport

Ashwagandha (Withania somnifera) - Its Antibacterial and Anticancer Activity
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  • Ashwagandha (Withania somnifera) - Its Antibacterial and Anticancer Activity
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  3. Vol. 66 (2024) /
  4. Health Sciences

Ashwagandha (Withania somnifera) - Its Antibacterial and Anticancer Activity

Authors

  • Aleksandra Mazurkiewicz Ludwik Rydygier Specialist Hospital in Kraków, Złotej Jesieni 1 Estate, 31-826 Kraków https://orcid.org/0009-0008-9427-9378
  • Wojciech Mądry Ludwik Rydygier Specialist Hospital in Kraków, Złotej Jesieni 1 Estate, 31-826 Kraków, Poland https://orcid.org/0009-0003-9434-0478
  • Magdalena Kołodziej Brothers Hospitallers Hospital in Kraków, Trynitarska 11, 31-061 Kraków, Poland https://orcid.org/0000-0002-6597-1559
  • Joanna Męczyńska St. John Paul II Mazovian Provincial Hospital in Siedlce, Poland, Księcia Józefa Poniatowskiego 26, 08-110 Siedlce, Poland https://orcid.org/0009-0002-0292-8032
  • Nazarii Saiuk Ludwik Rydygier Specialist Hospital in Kraków, Złotej Jesieni 1 Estate, 31-826 Kraków, Poland https://orcid.org/0000-0001-6722-0751
  • Michał Andrzej Kozicz Brothers Hospitallers Hospital in Kraków, Trynitarska 11, 31-061 Kraków, Poland https://orcid.org/0009-0001-4254-4087
  • Tomasz Seredyński St. Lucas Provincial Hospital Tarnów, Lwowska 178A, 33-100 Tarnów, Poland https://orcid.org/0009-0000-7806-0220
  • Adriana Wojciechowska The Medical University of Lublin, Aleje Racławickie 1, 20-059 Lublin, Poland https://orcid.org/0009-0006-9946-8448
  • Justyna Marcicka Ludwik Rydygier Specialist Hospital in Kraków, Złotej Jesieni 1 Estate, 31-826 Kraków, Poland https://orcid.org/0009-0003-1766-7397
  • Weronika Salasa Stefan Wyszynski Specialist Hospital in Lublin, Krasnicka 100, 20-718 Lublin, Poland https://orcid.org/0000-0002-8683-2582

DOI:

https://doi.org/10.12775/JEHS.2024.66.008

Keywords

ashwagandha, Withania Somnifera, antibacterial, anticancer, side effects, breast cancer

Abstract

Introduction

Ashwagandha, a traditional Indian plant, is gaining increasive attention from scientists worldwide due to its potential health benefits, especially in the context of its antibacterial and anticancer properties.

Aim of the study

The aim of this review was to discuss recent findings regarding the impact of Withania Somnifera on antibacterial effect and its potential applications in anticancer therapy.

Materials and methods:

The paper was created based on the Pubmed and Google Scholar database. The literature was reviewed using the keywards: ,,Ashwagandha”, ,,Withania Somnifera”, ,,antibacterial ”, ,,anticancer”, ,,side effects”, ,,breats cancer”.

Results

Studies have confirmed Withania Somnifera, exhibits significant anticacterial and anticancer effects. It inhibits the growth of both Gram-negative and Gram-positive bacteria. Futhermore, it demonstrates anticancer activity, especially in breast cancer, by stimulating apoptosis, induction of cytotoxic effects on cancerous cells and increasing cell sensitivity to radiation.

Conclusion

Despite promising results, futher research on the benefits of Ashwagandha, particulary in the long term, is essential. There is growing need of more research of the potencial benefits of Ashwagandha in the treatment of various disorders including cancer and bacterial infections and to develop more effective therapeutic strategies. The need for large randomized studies comparing long term clinical effectiveness is emphasized

References

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Published

2024-04-19

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MAZURKIEWICZ, Aleksandra, MĄDRY, Wojciech, KOŁODZIEJ, Magdalena, MĘCZYŃSKA, Joanna, SAIUK, Nazarii, KOZICZ, Michał Andrzej, SEREDYŃSKI, Tomasz, WOJCIECHOWSKA, Adriana, MARCICKA, Justyna and SALASA, Weronika. Ashwagandha (Withania somnifera) - Its Antibacterial and Anticancer Activity. Journal of Education, Health and Sport. Online. 19 April 2024. Vol. 66, p. 50081. [Accessed 6 July 2025]. DOI 10.12775/JEHS.2024.66.008.
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Vol. 66 (2024)

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Health Sciences

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Copyright (c) 2024 Aleksandra Mazurkiewicz, Wojciech Mądry, Magdalena Kołodziej, Joanna Męczyńska, Nazarii Saiuk, Michał Andrzej Kozicz, Tomasz Seredyński, Adriana Wojciechowska, Justyna Marcicka, Weronika Salasa

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