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Journal of Education, Health and Sport

A case of a patient with type 1 diabetes mellitus and anorexia nervosa with changes to the central nervous system
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A case of a patient with type 1 diabetes mellitus and anorexia nervosa with changes to the central nervous system

Authors

  • Armand Bajaka Department of Child Psychiatry, Medical University of Warsaw, Warsaw, Poland https://orcid.org/0009-0007-6051-8329

DOI:

https://doi.org/10.12775/JEHS.2024.63.010

Keywords

eating disorders, anorexia nervosa, diabetes mellitus type 1, vasculogenic changes, MRI

Abstract

Co-occurrence of anorexia nervosa (AN) and diabetes mellitus type 1 (T1DM) is an uncommon disease combination in clinical practice.  Treatment of T1DM may affect outcomes in AN patients due to self-modification of insulin dosage. In the presented case 14-year-old patient diagnosed with both T1DM and AN has been modifying her insulin-dependent treatment to prevent gaining weight. Undercontrolled glucose levels resulted in early-stage diabetic vascular complications in the central nervous system found in MRI.  Due to higher T1DM morbidity of eating disorders patients, adjustments and special control of insulin treatment and blood glucose levels as well as HbA1c should be maintained in the prevention of diabetic complications, especially in individuals with lower treatment compliance. As AN may lead to structural changes and a decrease in cognitive functions,  increased supervision of AN patients with T1DM can lower the risk of cumulative negative effects on the brain.

References

Russell-Jones D, Khan R. Insulin-associated weight gain in diabetes--causes, effects and coping strategies. Diabetes Obes Metab. 2007;9(6):799-812. doi:10.1111/j.1463-1326.2006.00686.x

Priesterroth L, Grammes J, Clauter M, Kubiak T. Diabetes technologies in people with type 1 diabetes mellitus and disordered eating: A systematic review on continuous subcutaneous insulin infusion, continuous glucose monitoring and automated insulin delivery. Diabet Med. 2021;38(7):e14581. doi:10.1111/dme.14581

Jones JM, Lawson ML, Daneman D, Olmsted MP, Rodin G. Eating disorders in adolescent females with and without type 1 diabetes: cross sectional study. BMJ. 2000;320(7249):1563-1566.

Weight gain associated with intensive therapy in the diabetes control and complications trial. The DCCT Research Group. Diabetes Care. 1988;11(7):567-573. doi:10.2337/diacare.11.7.567

Marcovecchio ML, Dalton RN, Daneman D, et al. A new strategy for vascular complications in young people with type 1 diabetes mellitus. Nat Rev Endocrinol. 2019;15(7):429-435. doi:10.1038/s41574-019-0198-2

Peterson CM, Fischer S, Young-Hyman D. Topical review: a comprehensive risk model for disordered eating in youth with type 1 diabetes. J Pediatr Psychol. 2015;40(4):385-390. doi:10.1093/jpepsy/jsu106

Mishriky BM, Cummings DM, Powell JR. Diabetes-Related Microvascular Complications - A Practical Approach. Prim Care. 2022;49(2):239-254. doi:10.1016/j.pop.2021.11.008

Giannopoulou EZ, Doundoulakis I, Antza C, et al. Subclinical arterial damage in children and adolescents with type 1 diabetes: A systematic review and meta-analysis. Pediatr Diabetes. 2019;20(6):668-677. doi:10.1111/pedi.12874

Biessels GJ, Deary IJ, Ryan CM. Cognition and diabetes: a lifespan perspective. Lancet Neurol. 2008;7(2):184-190. doi:10.1016/S1474-4422(08)70021-8

Biessels GJ, Reijmer YD. Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI?. Diabetes. 2014;63(7):2244-2252. doi:10.2337/db14-0348

Dogra V, Pankaj, Kumaran SS, et al. Evaluation of structural brain changes and their correlation with cognitive functions in adults with type 1 diabetes stratified by the age of diabetes onset: A cross-sectional study. Diabetes Metab Syndr. 2023;17(5):102768. doi:10.1016/j.dsx.2023.102768

Joos A, Klöppel S, Hartmann A, et al. Voxel-based morphometry in eating disorders: correlation of psychopathology with grey matter volume. Psychiatry Res. 2010;182(2):146-151. doi:10.1016/j.pscychresns.2010.02.004

Suchan B, Busch M, Schulte D, Grönemeyer D, Herpertz S, Vocks S. Reduction of gray matter density in the extrastriate body area in women with anorexia nervosa [published correction appears in Behav Brain Res. 2011 Mar 1;217(2):488. Grönermeyer, Dietrich [corrected to Grönemeyer, Dietrich]]. Behav Brain Res. 2010;206(1):63-67. doi:10.1016/j.bbr.2009.08.035

Titova OE, Hjorth OC, Schiöth HB, Brooks SJ. Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies. BMC Psychiatry. 2013;13:110. Published 2013 Apr 9. doi:10.1186/1471-244X-13-110

Seitz J, Bühren K, von Polier GG, Heussen N, Herpertz-Dahlmann B, Konrad K. Morphological changes in the brain of acutely ill and weight-recovered patients with anorexia nervosa. A meta-analysis and qualitative review. Z Kinder Jugendpsychiatr Psychother. 2014;42(1):7-18. doi:10.1024/1422-4917/a000265

Nickel K, Joos A, Tebartz van Elst L, et al. Recovery of cortical volume and thickness after remission from acute anorexia nervosa. Int J Eat Disord. 2018;51(9):1056-1069. doi:10.1002/eat.22918

Phillipou A, Rossell SL, Gurvich C, et al. Differences in regional grey matter volumes in currently ill patients with anorexia nervosa. Eur J Neurosci. 2018;47(2):177-183. doi:10.1111/ejn.13793

Solstrand Dahlberg L, Wiemerslage L, Swenne I, et al. Adolescents newly diagnosed with eating disorders have structural differences in brain regions linked with eating disorder symptoms. Nord J Psychiatry. 2017;71(3):188-196. doi:10.1080/08039488.2016.1250948

Curzio O, Calderoni S, Maestro S, et al. Lower gray matter volumes of frontal lobes and insula in adolescents with anorexia nervosa restricting type: Findings from a Brain Morphometry Study. Eur Psychiatry. 2020;63(1):e27. Published 2020 Mar 16. doi:10.1192/j.eurpsy.2020.19

Katzman DK, Zipursky RB, Lambe EK, Mikulis DJ. A longitudinal magnetic resonance imaging study of brain changes in adolescents with anorexia nervosa. Arch Pediatr Adolesc Med. 1997;151(8):793-797. doi:10.1001/archpedi.1997.02170450043006

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Published

2024-02-24

How to Cite

1.
BAJAKA, Armand. A case of a patient with type 1 diabetes mellitus and anorexia nervosa with changes to the central nervous system. Journal of Education, Health and Sport. Online. 24 February 2024. Vol. 63, pp. 139-145. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2024.63.010.
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Issue

Vol. 63 (2024)

Section

Medical Sciences

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Copyright (c) 2024 Armand Bajaka

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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