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Journal of Education, Health and Sport

The occurrence of skin lesions in patients with androgenization syndromes including the analysis of the results of hormonal tests
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The occurrence of skin lesions in patients with androgenization syndromes including the analysis of the results of hormonal tests

Authors

  • Mirela Niedzielska Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin
  • Artur Kotwas Katedra i Zakład Zdrowia Publicznego Pomorskiego Uniwersytetu Medycznego w Szczecinie
  • Paulina Zabielska Katedra i Zakład Zdrowia Publicznego Pomorskiego Uniwersytetu Medycznego w Szczecinie
  • Katarzyna Korabiusz Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin
  • Agata Wawryków Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin
  • Inga Janik Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin
  • Anna Fabian- Danielewska Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin

Keywords

androgenization syndrome, hormonal tests

Abstract

The androgenisation syndrome in women with endocrine disease is a major interdisciplinary problem. Based on the analysis of the literature, the problem was defined and the most important diseases resulting from the excess of androgens were discussed. Acne is the most commonly diagnosed skin disease in teens and young adults. It is often caused by an excess of androgens or skin hypersensitivity to normal levels.

 

The aim of the study was to analyze the effect of androgens on skin lesions in androgenisation syndromes.

 

Material and methodology: The analysis concerned the results of hormonal studies included

In the medical records 150 young women aged 16 to 36 years. The study group (group A) was 100 patients diagnosed with ovarian androgen syndrome. The control group consisted of 50 healthy women who did not meet the criteria of the study group.

 

Results: It was found that the majority of them were juvenile patients,

In addition, elevated androgens: SHBG (p = 0.016), DHEA-S (p <0.000), testosterone (p <0.000) and androstenedione (p = 0.007) were compared with those of the group control. There was a significant correlation (r = -0.420; p <0.000) between testosterone and androstenedione, SHBG and DHEA-S (r = -0.391; p <0.000), SHBG a (r = -0.272; p <0.009).

 

Conclusions: Among the most important hormones that can affect anogenesis are androgens, therefore a detailed understanding of the pathology associated with androgenisation is a must for gynecologists, dermatologists, endocrinologists, family physicians, pediatricians and cosmetologists. Youth acne is a significant clinical marker of androgenisation syndrome and can not be considered a temporary symptom of puberty in adolescents. Cosmetic procedures applied to the skin with acne may be ineffective without prior hormonal diagnosis.

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Published

2017-08-28

How to Cite

1.
NIEDZIELSKA, Mirela, KOTWAS, Artur, ZABIELSKA, Paulina, KORABIUSZ, Katarzyna, WAWRYKÓW, Agata, JANIK, Inga & FABIAN- DANIELEWSKA, Anna. The occurrence of skin lesions in patients with androgenization syndromes including the analysis of the results of hormonal tests. Journal of Education, Health and Sport [online]. 28 August 2017, T. 7, nr 8, s. 724–740. [accessed 21.3.2023].
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Vol. 7 No. 8 (2017)

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Articles

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