The Impact of diet on the digestive, cardiovascular and immune systems
DOI:
https://doi.org/10.12775/JEHS.2024.54.008Keywords
diet, digestive system, immune system, cardiovascular system, obesity, malnutrition, infectionAbstract
INTRODUCTION AND AIM OF WORK
One of the key factors shaping human health is diet. It serves as the foundation for the functioning of cells, organs, and the entire body. Properly chosen food has an impact, among other things, on the functioning of the immune, digestive, and cardiovascular systems.
MATERIALS AND METHODS
The objective of this study is to analyze the changes in the functioning of the cardiovascular, digestive, and immune systems through the application of different dietary approaches. For this purpose, an original questionnaire was developed. The questionnaire was distributed via social media (Telegram platform) in August 2023 among the population of Ukraine.
RESULTS
We collected a total of 94 surveys, with an average participant age of 26 years. A similar number of participants indicated consuming meals 3 times, 4 times, or 5 times a day. These were 23 individuals (24.47%), 25 individuals (26.6%), and 21 individuals (22.3%) respectively. The analysis of correlations revealed a negative correlation between the frequency of meal consumption and the frequency of infections (r = -0.21, p = 0.035). A significant relationship was also observed between body weight and the frequency of meal consumption (r = 0.34, p < 0.001). However, no significant relationship was found between following a special diet and body weight (p > 0.05).
CONCLUSIONS
The collected results suggest a connection between dietary habits and the frequency of infections as well as body weight. Interestingly, this relationship was related specifically to the frequency of meal consumption and was not linked to the intake of specific food groups. The obtained results highlight the significance of regular meal consumption in maintaining a healthy body weight and reducing the frequency of infections.
References
Pignatti C, D'Adamo S, Stefanelli C, Flamigni F, Cetrullo S. Nutrients and Pathways that Regulate Health Span and Life Span. Geriatrics (Basel). 2020 Nov 19;5(4):95. doi: 10.3390/geriatrics5040095.
Longo VD, Di Tano M, Mattson MP. Intermittent and periodic fasting, longevity and disease. Nat Aging. 2021 Jan;1(1):47-59. doi: 10.1038/s43587-020-00013-3
Pace LA, Crowe SE. Complex Relationships Between Food, Diet, and the Microbiome. Gastroenterol Clin North Am. 2016 Jun;45(2):253-65. doi: 10.1016/j.gtc.2016.02.004.
Rodríguez L, Cervantes E, Ortiz R. Malnutrition and gastrointestinal and respiratory infections in children: a public health problem. Int J Environ Res Public Health. 2011 Apr;8(4):1174-205. doi: 10.3390/ijerph8041174.
Gabriele M, Pucci L. Diet Bioactive Compounds: Implications for Oxidative Stress and Inflammation in the Vascular System. Endocr Metab Immune Disord Drug Targets. 2017 Nov 16;17(4):264-275. doi: 10.2174/1871530317666170921142055.
Calder PC. Omega-3 fatty acids and inflammatory processes. Nutrients. 2010 Mar;2(3):355-374. doi: 10.3390/nu2030355. Epub 2010 Mar 18.
Rubin LP, Ross AC, Stephensen CB, Bohn T, Tanumihardjo SA. Metabolic Effects of Inflammation on Vitamin A and Carotenoids in Humans and Animal Models. Adv Nutr. 2017 Mar 15;8(2):197-212. doi: 10.3945/an.116.014167.
Khan N, Khymenets O, Urpí-Sardà M, Tulipani S, Garcia-Aloy M, Monagas M, Mora-Cubillos X, Llorach R, Andres-Lacueva C. Cocoa polyphenols and inflammatory markers of cardiovascular disease. Nutrients. 2014 Feb 21;6(2):844-80. doi: 10.3390/nu6020844.
Kaulmann A, Bohn T. Carotenoids, inflammation, and oxidative stress--implications of cellular signaling pathways and relation to chronic disease prevention. Nutr Res. 2014 Nov;34(11):907-29. doi: 10.1016/j.nutres.2014.07.010.
Ma Y, Hébert JR, Li W, Bertone-Johnson ER, Olendzki B, Pagoto SL, Tinker L, Rosal MC, Ockene IS, Ockene JK, Griffith JA, Liu S. Association between dietary fiber and markers of systemic inflammation in the Women's Health Initiative Observational Study. Nutrition. 2008 Oct;24(10):941-9. doi: 10.1016/j.nut.2008.04.005.
Glaab E., Ostaszewski M. The Role of Spike-ACE2 Interaction in Pulmonary Blood Pressure Regulation. FAIRDOM Hub. [(accessed on 27 May 2020)]
Pohanka M. Role of oxidative stress in infectious diseases. A review. Folia Microbiol (Praha). 2013 Nov;58(6):503-13. doi: 10.1007/s12223-013-0239-5.
Venter, C., Eyerich, S., Sarin, T. Nutrition and the Immune System: A Complicated Tango. Nutrients. 2020;12(3), 818. doi:10.3390/nu12030818
Townsend N, Nichols M, Scarborough P, Rayner M. Cardiovascular disease in Europe 2015: epidemiological update. Eur Heart J. 2015 Oct 21;36(40):2673-4.
GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Jan 10;385(9963):117-71. doi: 10.1016/S0140-6736(14)61682-2.
Niu K, Momma H, Kobayashi Y, Guan L, Chujo M, Otomo A, Ouchi E, Nagatomi R. The traditional Japanese dietary pattern and longitudinal changes in cardiovascular disease risk factors in apparently healthy Japanese adults. Eur J Nutr. 2016 Feb;55(1):267-79. doi: 10.1007/s00394-015-0844-y.
Shimazu T, Kuriyama S, Hozawa A, Ohmori K, Sato Y, Nakaya N, Nishino Y, Tsubono Y, Tsuji I. Dietary patterns and cardiovascular disease mortality in Japan: a prospective cohort study. Int J Epidemiol. 2007 Jun;36(3):600-9. doi: 10.1093/ije/dym005.
Poulsen SK, Due A, Jordy AB, Kiens B, Stark KD, Stender S, Holst C, Astrup A, Larsen TM. Health effect of the New Nordic Diet in adults with increased waist circumference: a 6-mo randomized controlled trial. Am J Clin Nutr. 2014 Jan;99(1):35-45. doi: 10.3945/ajcn.113.069393.
Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Onning G, Landin-Olsson M, Herzig KH, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T, Overvad K, Bach Knudsen KE, Hedemann MS, Arner P, Dahlman I, Borge GI, Baardseth P, Ulven SM, Gunnarsdottir I, Jónsdóttir S, Thorsdottir I, Orešič M, Poutanen KS, Risérus U, Akesson B. Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome -- a randomized study (SYSDIET). J Intern Med. 2013 Jul;274(1):52-66. doi: 10.1111/joim.12044.
Roswall N, Li Y, Kyrø C, Sandin S, Löf M, Adami HO, Weiderpass E. No Association between Adherence to a Healthy Nordic Food Index and Colorectal Cancer: Results from a Swedish Cohort Study. Cancer Epidemiol Biomarkers Prev. 2015 Apr;24(4):755-7. doi: 10.1158/1055-9965.EPI-14-1314.
Wang F, Zheng J, Yang B, Jiang J, Fu Y, Li D. Effects of Vegetarian Diets on Blood Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc. 2015 Oct 27;4(10):e002408. doi: 10.1161/JAHA.115.002408.
Yiannakou I, Barber LE, Li S, Adams-Campbell LL, Palmer JR, Rosenberg L, Petrick JL. A Prospective Analysis of Red and Processed Meat Intake in Relation to Colorectal Cancer in the Black Women's Health Study. J Nutr. 2022 May 5;152(5):1254-1262. doi: 10.1093/jn/nxab419.
Cross AJ, Ferrucci LM, Risch A, Graubard BI, Ward MH, Park Y, Hollenbeck AR, Schatzkin A, Sinha R. A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association. Cancer Res. 2010 Mar 15;70(6):2406-14. doi: 10.1158/0008-5472.CAN-09-3929. Epub 2010 Mar 9.
Steck SE, Murphy EA. Dietary patterns and cancer risk. Nat Rev Cancer. 2020 Feb;20(2):125-138. doi: 10.1038/s41568-019-0227-4.
Halliwell B. The antioxidant paradox: less paradoxical now? Br J Clin Pharmacol. 2013 Mar;75(3):637-44. doi: 10.1111/j.1365-2125.2012.04272.x.
Subramaniam S, Selvaduray KR, Radhakrishnan AK. Bioactive Compounds: Natural Defense Against Cancer? Biomolecules. 2019 Nov 21;9(12):758. doi: 10.3390/biom9120758.
González CA, Salas-Salvadó J. The potential of nuts in the prevention of cancer. Br J Nutr. 2006 Nov;96 Suppl 2:S87-94. doi: 10.1017/bjn20061868.
Hellwig JP, Otten JJ, Meyers LD. Dietary Reference Intakes∷ the Essential Guide to Nutrient Requirements. 2006
Katz DL, Meller S. Can we say what diet is best for health? Annu Rev Public Health. 2014;35:83-103. doi: 10.1146/annurev-publhealth-032013-182351.
Golbidi S, Daiber A, Korac B. Health Benefits of Fasting and Caloric Restriction. Curr Diab Rep. 2017; 17(12):123. doi: 10.1007/s11892-017-0951-7.
Marrone G, Guerriero C, Palazzetti D, et al. Vegan Diet Health Benefits in Metabolic Syndrome. Nutrients. 2021;13(3):817. Published 2021 Mar 2. doi:10.3390/nu13030817
Kahleova H, Petersen KF, Shulman GI, et al. Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial JAMA Netw Open. 2020;3(11):e2025454. Published 2020 Nov 2. doi:10.1001/jamanetworkopen.2020.25454
Bali A, Naik R. The Impact of a Vegan Diet on Many Aspects of Health: The Overlooked Side of Veganism. Cureus. 2023;15(2):e35148. Published 2023 Feb 18. doi:10.7759/cureus.35148
Soares MJ, Müller MJ. Editorial: Nutrition and COVID-19. Eur J Clin Nutr. 2020;74(6):849. doi:10.1038/s41430-020-0647-y
Alkhatib A. Antiviral Functional Foods and Exercise Lifestyle Prevention of Coronavirus. Nutrients. 2020;12(9):2633. Published 2020 Aug 28. doi:10.3390/nu12092633
Angelidi AM, Kokkinos A, Katechaki E, Ros E, Mantzoros CS. Mediterranean diet as a nutritional approach for COVID-19. Metabolism. 2021;114:154407. doi:10.1016/j.metabol.2020.154407
Kazaks A, Stern JS. Obesity: food intake. Prim Care. 2003;30(2):301-vi. doi:10.1016/s0095-4543(03)00011-3
Ziauddeen H, Alonso-Alonso M, Hill JO, Kelley M, Khan NA. Obesity and the neurocognitive basis of food reward and the control of intake. Adv Nutr. 2015;6(4):474-486. Published 2015 Jul 15. doi:10.3945/an.115.008268
Hill JO, Wyatt HR, Peters JC. Energy balance and obesity. Circulation. 2012;126(1):126-132. doi:10.1161/CIRCULATIONAHA.111.087213
Fletcher PC, Kenny PJ. Food addiction: a valid concept? [published correction appears in Neuropsychopharmacology. 2018 Dec 7;:]. Neuropsychopharmacology. 2018;43(13):2506-2513. doi:10.1038/s41386-018-0203-9
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Copyright (c) 2024 Mateusz Kobierecki, Oliwia Kwaśniewska, Jakub Misiak, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Martyna Kępczyk
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