The impact of consumed coffee on the digestive system - review of the latest research
DOI:
https://doi.org/10.12775/JEHS.2024.53.003Keywords
coffee, caffeine, digestive system, digestion, cancerAbstract
Introduction
Coffee stands as the second most widely consumed beverage globally, following water.[1] Recent research on the effects of coffee consumption underscores its positive outcomes when adhering to recommended doses—typically ranging from 2 to 5 cups a day, amounting to a maximum of 400 mg of caffeine daily. This newfound perspective highlights the potential benefits of moderate coffee intake on our overall health and well-being.
Aim of the study
The objective of this study was to comprehensively review the existing knowledge regarding the impact of coffee consumption on diverse aspects of the gastrointestinal tract.
Materials and methodology
A literature review was conducted utilizing the PubMed, Google Scholar, and Google databases. Articles were systematically searched in both English and Polish, employing the keywords: coffee, caffeine, digestive system, digestion, and cancer.
Results
Recent research highlights coffee's diverse benefits, aiding digestion, hastening transit, and showing potential in cancer prevention. It stimulates gastric acid, enhances bile and pancreatic secretion, reduces gallstone risk, promotes large intestine movement, and modulates intestinal flora. Importantly, coffee isn't a primary factor in conditions like reflux, ulcers, inflammatory bowel diseases, or cancer.
Conclusions
Further research is essential to deepen our understanding of coffee's impact on the digestive system and its systemic effects on the body. Additionally, promoting awareness of safe daily caffeine doses that can contribute to health is worthwhile.
References
Adler G, Nędzarek A, Tórz A. (2019). Concentrations of Selected Metals (Na, K, Ca, Mg, Fe, Cu, Zn, Al, Ni, Pb, Cd) in Coffee. SlovenianJournal of Public Health, 58(4), 187-193. doi: 10.2478/sjp-2019-0024.
Safe S, Kothari J, Hailemariam A, Upadhyay S, Davidson LA, Chapkin RS. Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action. International Journal of MolecularSciences. 2023;24(3):2706. doi:10.3390/ijms24032706
Murray A, Traylor J. Caffeine Toxicity. In: StatPearls. StatPearls Publishing; 2023. Available from: http://www.ncbi.nlm.nih.gov/books/NBK532910/ Bookshelf ID: NBK532910
Ding Q, Xu YM, Lau ATY. The Epigenetic Effects of Coffee. Molecules. 2023;28(4):1770. doi:10.3390/molecules28041770
Silvia C, Serena S, Chiara M, et al. Diagnosis of GERD in typical and atypical manifestations. Acta Biomed. 2018;89(Suppl 8):33-39. doi:10.23750/abm.v89i8-S.7963
Taraszewska A. Risk factors for gastroesophageal reflux disease symptoms related to lifestyle and diet. RoczPanstwZaklHig. 2021;72(1):21-28. doi:10.32394/rpzh.2021.0145
Wei TY, et al. (2019). The role of tea and coffee in the development of gastroesophageal reflux disease. Tzu Chi MedicalJournal, 31, 169-176.
Helle K, Bálint L, Szekeres V, Ollé G, Rosztóczy A. Prevalence of reflux-related symptoms in South-Hungarian blood donor volunteers. PLoS One. 2022;17(3):e0265152. doi:10.1371/journal.pone.0265152
Aldoori WH, Giovannucci EL, Stampfer MJ, Rimm EB, Wing AL, Willett WC. A prospective study of alcohol, smoking, caffeine, and the risk of duodenal ulcer in men. Epidemiology. 1997;8(4):420-424. doi:10.1097/00001648-199707000-00012
Bacha D, Walha M, Ben Slama S, et al. Chronic gastritis classifications. Tunis Med. 2018;96(7):405-410.
L K, J J, R S, N RL, A V, M S. Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options. Journal of ClinicalMedicine. 2019;8(2). doi:10.3390/jcm8020179
Rosenstock S, Jørgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population-based prospective cohort study comprising 2416 Danish adults. Gut. 2003;52(2):186-193. doi:10.1136/gut.52.2.186
Di Ciaula A, Garruti G, Lunardi Baccetto R, et al. Bile Acid Physiology. Annals of Hepatology. 2017;16(Suppl. 1): s4-s14. doi:10.5604/01.3001.0010.5493
Jones MW, Small K, Kashyap S, Deppen JG. Physiology, Gallbladder. In: StatPearls. StatPearls Publishing; 2023. Available from: http://www.ncbi.nlm.nih.gov/books/NBK482488/
Nehlig A. Effects of Coffee on the Gastrointestinal Tract: A Narrative Review and Literature Update. Nutrients. 2022;14(2):399. doi:10.3390/nu14020399
Trefts E, Gannon M, Wasserman DH. The liver. Current Biology. 2017;27(21):R1147-R1151. doi:10.1016/j.cub.2017.09.019
Nieber K. The Impact of Coffee on Health. Planta Med. 2017;83(16):1256-1263. doi:10.1055/s-0043-115007
Wadhawan MA, AC. Coffee and liver disease. Journal of Clinical and Experimental Hepatology. 2016;6:40-46. doi:10.1016/j.jceh.2016.02.003
Liu FW, X; Wu, G; Chen, L; Hu, P; Ren, H; Hu, H. Coffee consumption decreases risks for hepatic fibrosis and cirrhosis: A meta-analysis. PLoS One. 2015;10:e0142457. doi:10.1371/journal.pone.0142457
Ruhl CEE JE. Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States. Gastroenterology. 2005;128:24-32. doi:10.1053/j.gastro.2004.09.075
Shim SG, J D W; Kim, E K; Saeed, W K; Lee, K N; Lee, H L; Lee, O Y; Choi, H S; Yoon, BC. Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model. Journal of Gastroenterology and Hepatology. 2013;28:1877-1884. doi:10.1111/jgh.12317
Klatsky AL, M C; Udaltsova, N; Friedman, GD. Coffee, cirrhosis, and transaminase enzymes. Archives of Internal Medicine. 2006;166:1190-1195. doi:10.1001/archinte.166.11.1190
Hodge AL, S; Goh, E; Wong, O; Marsh, P; Knight, V; Sievert, W; de Courten, B. Coffee intake is associated with a lower liver stiffness in patients with non-alcoholic fatty liver disease, hepatitis C, and hepatitis B. Nutrients. 2017;9:56-64. doi:10.3390/nu9010056
Kesuma Y, Sekartini R, Timan IS, et al. Irritable bowel syndrome in Indonesian adolescents. J Pediatr (Rio J). 2020;97(2):197-203. doi:10.1016/j.jped.2020.02.001
Piric M, Pasic F, Rifatbegovic Z, Konjic F. The Effects of Drinking Coffee While Recovering from Colon and Rectal Resection Surgery. MedicalArchives. 2015;69(6):357-361. doi:10.5455/medarh.2015.69.357-361
Moco S. et al. (2012) Metabolomics view on gut microbiome modulation by polyphenol-rich foods. Journal of Proteome Research, 11:4781-4790.
Mills C.E. et al. (2015) In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth. British Journal of Nutrition, 113:1220-7.
Sipponen P, Maaroos HI. Chronic gastritis. Scandinavian Journal of Gastroenterology. 2015;50(6):657-667. doi:10.3109/00365521.2015.1019918
Yang H, Hu B. Immunological Perspective: Helicobacter pylori Infection and Gastritis. MediatorsInflamm. 2022;2022:2944156. doi:10.1155/2022/2944156
Wl T, T T. Human liver model systems in a dish. Development, Growth & Differentiation. 2021;63(1). doi:10.1111/dgd.12708
Chiang JYL, Ferrell JM. Bile Acid Metabolism in Liver Pathobiology. Gene Expression. 2018;18(2):71-87. doi:10.3727/105221618X15156018385515
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Nina Taborska, Anna Martyka, Martyna Kubicka Figiel, Przemysław Ujma
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 896
Number of citations: 0