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Journal of Education, Health and Sport

Peculiarities of the formation of exocrine pancreatic insufficiency in patients with primary osteoarthritis under conditions of comorbidity
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Peculiarities of the formation of exocrine pancreatic insufficiency in patients with primary osteoarthritis under conditions of comorbidity

Authors

  • Iryna Halabitska I. Horbachevsky Ternopil National Medical University https://orcid.org/0000-0002-9028-7230

DOI:

https://doi.org/10.12775/JEHS.2023.48.01.008

Keywords

primary osteoarthritis, exocrine pancreatic insufficiency, type 2 diabetes, chronic pancreatitis, chronic cholecystitis, chronic gastritis, chronic duodenitis

Abstract

Summary.  The comorbidity of primary OA and diseases of the gastrointestinal tract, which EPI accompanies, is an extremely relevant, complex, and unstudied problem of modern medicine, as it has a number of unsolved problems both in the treatment and rehabilitation of such patients. Common pathogenetic mechanisms of the progression of such comorbidity often have a mutually aggravating effect, which requires further study.

The aim of the study is to analyze the changes in indicators of exocrine pancreatic insufficiency (EPI) in patients with primary OA under the conditions of comorbidity with diseases of the gastrointestinal tract (GI).

Research material and methods. 304 patients with primary OA in comorbidity with diseases of the gastrointestinal tract accompanied by non-exacerbation EPI were examined. The comparison group consisted of 30 practically healthy individuals who did not have clinical, anamnestic, and instrumental signs of diseases of the gastrointestinal tract and joints.

Results and discussion. It was established that in patients with primary OA in comorbidity with diseases that are accompanied by EPI, the levels of EPI indicators were statistically significantly different depending on the etiology of EPI.

Conclusion. Post hoc analysis established the ranking of the pathology of the gastrointestinal tract, accompanied by EPI, according to the indicators of EPI in primary OA, which was located as follows, starting from the highest: CP ˃ T2DM ˃ chronic non-calculous cholecystitis and functional diseases of the gallbladder and biliary system ˃ chronic gastroduodenitis (p ˂0.05).

References

R.R.Bannuru, M.C.Osani, E.E.Vaysbrot OARSI Guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis Osteoarthritis and Cartilage. 2019;27(11):1578-1589. doi.org/10.1016/j.joca.2019.06.011

Sakellariou G, Conaghan PG, Zhang W, et al. EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis Ann Rheum Dis. 2017;76:1484–1494. doi:10.1136/annrheumdis-2016-210815

Babinets, L.S., Halabitska, I.M. Chronic inflammatory process and bone tissue changes in patients with osteoarthritis and exocrine pancreatic insufficiency Lekarsky Obzor. 2020; 69 (1): 7-10.

Вabinets L.S., Halabitska I.M., Kotsaba Y.Y. et al. The effect of the proteolisis’ system activity for the trophological status of patients with osteoarthritis and exocrine insufficiency of pancreas. Wiadomosci lekarskie (Warsaw, Poland: 1960). 2018; 71(2 pt 1): 273-276.

Babinets, L.S., Halabitska, I.M. Characteristics of joint pain in patients with primary osteoarthritis and comorbid conditions with exocrine pancreatic insufficiency Lekarsky Obzor. 2021;70(2):62-64.

Babinets L.S., Zemlyak O.S., Halabitska I.M., Sasyk H.M., Onufryk Z.Ya. Dependence of pancreas functional capacity at chronic pancreatitis on endotoxicosis and other metabolic factors Wiadomosci lekarskie. 2021; №74(4): 869-874.

Chen H-, Yang F-, Lee T-, Liou T-, Escorpizo R, Chen H-. Effectiveness of interferential current therapy in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Sci Rep. 2022;12(1).

Neogi T, Zhang Y. Epidemiology of Osteoarthritis. Rheum Dis Clin North Am. 2013;39(1):1-19.

Stanborough RO, Bestic JM, Peterson JJ. Shoulder Osteoarthritis. Radiol Clin North Am. 2022;60(4):593-603.

Neogi, T. The epidemiology and impact of pain in osteoarthritis. Osteoarthritis and Cartilage. 2013;21(9):1145-1153. doi:10.1016/j.joca.2013.03.018

Richette P, Poitou C, Garnero P, Vicaut E, Bouillot J-, Lacorte J-, et al. Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis. Ann Rheum Dis. 2011;70(1):139-144.

Horgan R, Pierce-Williams R, Saccone G, Berghella V. Reminder systems to increase compliance with glucose logging in gestational diabetes: a systematic review and meta-analysis. American J Obstet Gynecol MFM. 2022;4(3).

Khalifeh A, Khosla J, Cantor E, Quist-Nelson J, Saccone G, Tumas J, et al. A reminder system for postpartum diabetes screening after gestational diabetes: a randomized clinical trial. J Matern -Fetal Neonatal Med. 2021.

Carmichael L, Keske MA, Betik AC, Parker L, Brayner B, Roberts-Thomson KM, et al. Is vascular insulin resistance an early step in diet-induced whole-body insulin resistance? Nutr Diabetes. 2022;12(1).

Dahlhamer, J.M., Lucas, J., Zelaya, C., et al. Prevalence of chronic pain and high-impact chronic pain among adults — United States, 2016 Morbidity and Mortality Weekly Report 2018;67 (36):1001-1006. doi: 10.15585/mmwr.mm6736a2

Parkoohi, P.I., Amirzadeh, K., Mohabbati, V., et al. Satisfaction with chronic pain treatment Anesthesiology and Pain Medicine 2015 5 (4), art. no. e23528, 5 p. doi: 10.5812/aapm.23528

Teigland, T., Iversen, M.M., Sangnes, D.A., et al. A longitudinal study on patients with diabetes and symptoms of gastroparesis – associations with impaired quality of life and increased depressive and anxiety symptoms Journal of Diabetes and its Complications. 2018;32 (1):89-94.

Wardian, J.L., Tate, J., Folaron, I., et al. Who's distressed? A comparison of diabetes-related distress by type of diabetes and medication

Patient Education and Counseling. 2018;101 (8):1490-1495.

Firouzjaei A, Li G.C, Wang N, Liu W.X., et al. Comparative evaluation of the therapeutic effect of metformin monotherapy with metformin and acupuncture combined therapy on weight loss and insulin sensitivity in diabetic patients Nutrition & Diabetes. 2016;6(e209).

Altman, R.D., Bedi, A., Karlsson, J., Sancheti, P., Schemitsch, E. Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee American Journal of Sports Medicine. 2016;44 (8):2158-2165.

Jean, Y.-H., Wen, Z.-H., Chang, Y.-C., Lee, H.-S., Hsieh, S.-P., Wu, C.-T., Yeh, C.-C., Wong, C.-S. Hyaluronic acid attenuates osteoarthritis development in the anterior cruciate ligament-transected knee: Association with excitatory amino acid release in the joint dialysate Journal of Orthopaedic Research. 2006;24 (5):1052-1061.

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Published

2023-11-05

How to Cite

1.
HALABITSKA, Iryna. Peculiarities of the formation of exocrine pancreatic insufficiency in patients with primary osteoarthritis under conditions of comorbidity. Journal of Education, Health and Sport. Online. 5 November 2023. Vol. 48, no. 1, pp. 125-134. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2023.48.01.008.
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Vol. 48 No. 1 (2023)

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Research Articles

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Copyright (c) 2023 Iryna Halabitska

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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