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Journal of Education, Health and Sport

Study of the effect of external use of a brown algae product on the structural-functional continuum
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Study of the effect of external use of a brown algae product on the structural-functional continuum

Authors

  • B. Nasibullin Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine
  • S. Gushcha Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine
  • Yu. Dekhtyar Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine
  • V. Volyanska Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine

DOI:

https://doi.org/10.12775/JEHS.2023.47.01.007

Keywords

product from brown algae, liver, structural-functional continuum

Abstract

The authors, in a study on 25 outbred Wistar white rats weighing 180-200 g, determined the effect of Lamidana (a product from sea brown algae) on the structural-functional continuum, that is, the correlation of the functional activity of the liver parenchyma and its structural characteristics. Methods. The detoxifying function of the liver was studied by the duration of sleep of animals due to the action of anesthesia - intraperitoneal administration of sodium thiopental (estimate the rate of metabolism of thiopental, carried out by the cytochrome-P-450-dependent monooxygenase system of hepatocytes). The structural and functional state of the liver parenchyma was assessed according to the study of histological preparations. The results of the studies showed that under the influence of the external application of "Lamidin" in the test rats, the liver1s detoxification function is enhanced (significantly significant decrease in the duration of sleep of animals). At the same time, structural signs of increased functional activity of hepatocytes are determined in the parenchyma. Conclusions. The authors believe that "Lamidan", due to the peculiarities of its chemical composition, enhances the metabolic and functional activity of hepatocytes but does not damage the correlative relationships between the structure and function of hepatocytes.

References

Sharifi-Rad M, Anil Kumar NV, Zucca P, Varoni EM, Dini L, Panzarini E, et al. Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases. Front Physiol. 2020 Jul 2;11:694. DOI: 10.3389/fphys.2020.00694.

van der Kooij MA. The impact of chronic stress on energy metabolism. Molecular and Cellular Neuroscience. 2020;107:103525. https://doi.org/10.1016/j.mcn.2020.103525.

Gozhenko AІ, Hryshko YuM. Chronic stress and its metabolic support. Actual Problems of the Modern Medicine. 2019;4(68):123-129. DOI: 10.31718/2077-1096.19.4.123. (in Ukrainian).

Shi M, Gu J, Wu H, Rauf A, Emran TB, et al. Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce-A Comprehensive Review. Antioxidants (Basel). 2022 Jun 13;11(6):1158. DOI: 10.3390/antiox11061158.

Quattrini S, Pampaloni B, Brandi ML. Natural mineral waters: chemical characteristics and health effects. Clin Cases Miner Bone Metab. 2016 Sep-Dec;13(3):173-180. DOI: 10.11138/ccmbm/2016.13.3.173.

Nasibullin BA, Gushcha SG, Dekhtyar YuN, Volyanska VS, Plakida AL. Experimental substantiation of the use of highly mineralized bromine chloride sodium water to correct the functional-metabolic continuum in rats with a model of distress. Journal of Education, Health and Sport. 2023;13(5):124-137. https://apcz.umk.pl/JEHS/article/view/44668.

López-Hortas L, Flórez-Fernández N, Torres MD, Ferreira-Anta T, Casas MP, et al. Applying Seaweed Compounds in Cosmetics, Cosmeceuticals and Nutricosmetics. Mar Drugs. 2021 Sep 29;19(10):552. DOI: 10.3390/md19100552.

Ismail MM, El Zokm GM, Miranda Lopez JM. Nutritional, bioactive compounds content, and antioxidant activity of brown seaweeds from the Red Sea. Front Nutr. 2023 Jul 26;10:1210934. DOI: 10.3389/fnut.2023.1210934.

Blikra MJ, Henjum S, Aakre I. Iodine from brown algae in human nutrition, with an emphasis on bioaccessibility, bioavailability, chemistry, and effects of processing: A systematic review. Compr Rev Food Sci Food Saf. 2022 Mar;21(2):1517-1536. DOI: 10.1111/1541-4337.12918.

Silva A, Cassani L, Grosso C, Garcia-Oliveira P, Morais SL, et al. Recent advances in biological properties of brown algae-derived compounds for nutraceutical applications. Crit Rev Food Sci Nutr. 2022 Aug 29:1-29. DOI: 10.1080/10408398.2022.2115004.

Order of Ministry of Education and Science, Youth and Sport of Ukraine No. 249 dated 01.03.2012.]. https://zakon.rada.gov.ua/laws/show/z0416-12#Text. (in Ukrainian).

Stefanov OV. Preclinical studies of medicinal products: methodical recommendations. Kyiv. 2001. 527 s. (in Ukrainian).

Lee I-S, Ko S-J, Lee YN, Lee G, Rahman MH, Kim B. The Effect of Laminaria japonica on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action. Nutrients. 2022;14(15):3046. https://doi.org/10.3390/nu14153046.

Afonso NC, Catarino MD, Silva AMS, Cardoso SM. Brown Macroalgae as Valuable Food Ingredients. Antioxidants (Basel). 2019 Sep 2;8(9):365. DOI: 10.3390/antiox8090365.

Wertz PW. Roles of Lipids in the Permeability Barriers of Skin and Oral Mucosa. Int J Mol Sci. 2021 May 15;22(10):5229. DOI: 10.3390/ijms22105229.

Babov K, Gushcha S, Koieva K, Strus O, Nasibullin B, Dmitrieva G, Аrabadji M, Plakida A. Comparative assessment of biological activity of peloids of Ukraine of different genesis. Balneo Research Journal. 2020;11(4):467–471. DOI: 10.12680/balneo.2020.380.

Jung EC, Maibach HI. Animal models for percutaneous absorption. J Appl Toxicol. 2015 Jan;35(1):1-10. DOI: 10.1002/jat.3004.

Gushcha S, Nasibullin B, Nikolaieva G, Plakida A. External use of radon and sulfide mineral waters in the treatment of experimental arthrosis. Balneo and PRM Research Journal. 2022;13(4):528. http://bioclima.ro/Balneo528.pdf.

N'Da DD. Prodrug strategies for enhancing the percutaneous absorption of drugs. Molecules. 2014 Dec 12;19(12):20780-807. doi: 10.3390/molecules191220780.

Polshchakova TV, Gushcha SG, Bevz LV, Plakida AL. The use of radon baths in the rehabilitation of patients with osteochondrosis Eur Rev Med Pharmacol Sci. 2022;26(17):6107-6109. DOI: 10.26355/eurrev_202209_29627.

Gálvez I, Torres-Piles S, Ortega-Rincón E. Balneotherapy, Immune System, and Stress Response: A Hormetic Strategy? Int J Mol Sci. 2018 Jun 6;19(6):1687. DOI: 10.3390/ijms19061687.

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Published

2023-08-29

How to Cite

1.
NASIBULLIN, B., GUSHCHA, S., DEKHTYAR, Yu. and VOLYANSKA, V. Study of the effect of external use of a brown algae product on the structural-functional continuum. Journal of Education, Health and Sport. Online. 29 August 2023. Vol. 47, no. 1, pp. 75-83. [Accessed 2 July 2025]. DOI 10.12775/JEHS.2023.47.01.007.
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Vol. 47 No. 1 (2023)

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Research Articles

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Copyright (c) 2023 B. Nasibullin, S. Gushcha, Yu. Dekhtyar, V. Volyanska

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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