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Journal of Education, Health and Sport

Ehlers-Danlos Syndrome - living with chronic pain. Current knowledge of the disease
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Ehlers-Danlos Syndrome - living with chronic pain. Current knowledge of the disease

Authors

  • Joanna Olszak Warszawski Uniwersytet Medyczny https://orcid.org/0009-0004-0211-1449
  • Wojciech Kapłan Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0003-2270-0318
  • Dominika Rachwał Medical University of Warsaw https://orcid.org/0009-0001-9104-0459
  • Ewa Piątek Uniwersytet Medyczny w Lublinie https://orcid.org/0009-0000-9051-5777
  • Karolina Zalewa Medical University of Warsaw https://orcid.org/0009-0004-0610-6866
  • Lidia Bartoszek Medical University of Warsaw https://orcid.org/0009-0000-1656-7325
  • Magdalena Czelej Samodzielny Publiczny Szpital Kliniczny SPSK4 w Lublinie, Polska https://orcid.org/0000-0002-3717-4261
  • Hubert Stachowicz Uniwersytet Medyczny w Lublinie https://orcid.org/0009-0003-5906-1350
  • Joanna Mazurek Uniwersytet Medyczny w Lublinie https://orcid.org/0009-0005-0300-7798

DOI:

https://doi.org/10.12775/JEHS.2023.19.01.015

Keywords

multidisciplinary therapy, joint hypermobility, chronic pain, Ehlers-Danlos syndrome

Abstract

Ehlers Danlos Syndrome (EDS) is a group of the most common inherited connective tissue disorders. The main symptoms of this syndrome are excessive skin flexibility, joint hypermobility and blood vessels fragility. The diagnosis is based on clinical symptoms, but to confirm the type of EDS, it is necessary to identify the collagen-encoding gene or protein interacting with it. The group of Ehlers and Danlos diseases include fourteen types, the most common are classic, vascular, hypermobile, arthrochalasis, kyphoscoliotic and dermatosparaxis. [15] Connective tissue plays a key role in the process of movement, constituting the main component of bones, joint cartilage, tendons, ligaments and intervertebral discs. In addition, connective tissue is a part of every internal organ including the intestines and parenchymal organs and the cardiovascular system.[19] For this reason, patients with EDS show symptoms of many diseases, including respiratory, muscular, skeletal and vascular. Women suffering from EDS often struggle with complications during their pregnancies. Psychological and emotional issues are also common.[6] However, the most noticeable and debilitating symptom of EDS is pain, which is often severe and chronic. The pain occurs in approximately 90% or more of EDS patients.[8] Successful pain management in patients with EDS is a major challenge for specialists. The treatment involves non-steroidal anti-inflammatory drugs, acetaminophen, opioids and physiotherapy. Also marijuana, traditional chinese treatments, herbal remedies are considered to reduce the severity of the symptoms. [9] During the creation of this article, the authors analyzed the clinically relevant knowledge of EDS treatment and management based on research published on Pubmed.

References

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Viviana Guerrieri , Alberto Polizzi , Laura Caliogna , Alice Maria Brancato , Alessandra Bassotti , Camilla Torriani , Eugenio Jannelli, Mario Mosconi, Federico Alberto Grassi, Gianluigi Pasta Pain in Ehlers-Danlos Syndrome: A Non-Diagnostic Disabling Symptom? Healthcare (Basel). 2023 Mar 24;11(7):936. doi: 10.3390/healthcare11070936.

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Published

2023-09-19

How to Cite

1.
OLSZAK, Joanna, KAPŁAN, Wojciech, RACHWAŁ, Dominika, PIĄTEK, Ewa, ZALEWA, Karolina, BARTOSZEK, Lidia, CZELEJ, Magdalena, STACHOWICZ, Hubert and MAZUREK, Joanna. Ehlers-Danlos Syndrome - living with chronic pain. Current knowledge of the disease. Journal of Education, Health and Sport. Online. 19 September 2023. Vol. 19, no. 1, pp. 158-169. [Accessed 20 May 2025]. DOI 10.12775/JEHS.2023.19.01.015.
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Vol. 19 No. 1 (2023)

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Review Articles

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Copyright (c) 2023 Joanna Olszak, Wojciech Kapłan, Dominika Rachwał, Ewa Piątek, Karolina Zalewa, Lidia Bartoszek, Magdalena Czelej, Hubert Stachowicz, Joanna Mazurek

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