The impact of the SARS-CoV-2 infection on the risk of developing preeclampsia
DOI:
https://doi.org/10.12775/JEHS.2023.43.01.001Keywords
pregnancy, COVID-19, SARS-CoV-2 pandemic, preeclampsiaAbstract
Introduction and purpose:
The COVID-19 pandemic has significantly affected the health, life and quality of life of many people around the world. It caused huge changes in the daily functioning of entire societies. Pregnant women are a unique group of people who are particularly at risk. They are accompanied by fear for their health, but also fear of the impact of the disease on their offspring. The pandemic has also caused new challenges for mothers-to-be that have not occurred so far. In this paper, we would like to present the current state of knowledge on the impact of SARS-CoV-2 infection on the risk of developing pre-eclampsia.
State of knowledge:
We analyzed studies showing the impact of COVID-19 infection on the health of pregnant women, especially on the risk of developing pre-eclampsia. Data from many studies are contradictory. Some studies do not indicate a significant impact of coronavirus infection on the development of pre-eclampsia. Some of them confirm a higher incidence of pre-eclampsia in pregnant women with confirmed COVID-19 infection.
Conclusions:
Despite the experience gained, there are still many unknowns. Thanks to research, we have more and more knowledge about the course of COVID-19 in pregnant women and its impact on their lives. Many observations are still needed to formulate clear conclusions about the impact of COVID-19 on the risk of developing pre-eclampsia. It is also necessary to continue to educate women, encourage compliance with the recommendations of doctors and the World Health Organization to prevent the spread of coronavirus.
References
https://www.who.int/health-topics/coronavirus#tab=tab_1
Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, Ren R, Leung KSM, Lau EHY, Wong JY, Xing X, Xiang N, Wu Y, Li C, Chen Q, Li D, Liu T, Zhao J, Liu M, Tu W, Chen C, Jin L, Yang R, Wang Q, Zhou S, Wang R, Liu H, Luo Y, Liu Y, Shao G, Li H, Tao Z, Yang Y, Deng Z, Liu B, Ma Z, Zhang Y, Shi G, Lam TTY, Wu JT, Gao GF, Cowling BJ, Yang B, Leung GM, Feng Z. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29. PMID: 31995857; PMCID: PMC7121484.
https://www.who.int/europe/emergencies/situations/covid-19
https://www.who.int/health-topics/coronavirus#tab=tab_3
Wastnedge EAN, Reynolds RM, van Boeckel SR, Stock SJ, Denison FC, Maybin JA, Critchley HOD. Pregnancy and COVID-19. Physiol Rev. 2021 Jan 1;101(1):303-318. doi: 10.1152/physrev.00024.2020. Epub 2020 Sep 24. PMID: 32969772; PMCID: PMC7686875.
Poon LC, Yang H, Kapur A, Melamed N, Dao B, Divakar H, McIntyre HD, Kihara AB, Ayres-de-Campos D, Ferrazzi EM, Di Renzo GC, Hod M. Global interim guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium from FIGO and allied partners: Information for healthcare professionals. Int J Gynaecol Obstet. 2020 Jun;149(3):273-286. doi: 10.1002/ijgo.13156. Epub 2020 Apr 28. PMID: 32248521; PMCID: PMC9087575.
Celewicz A, Celewicz M, Michalczyk M, Woźniakowska-Gondek P, Krejczy K, Misiek M, Rzepka R. SARS CoV-2 infection as a risk factor of preeclampsia and pre-term birth. An interplay between viral infection, pregnancy-specific immune shift and endothelial dysfunction may lead to negative pregnancy outcomes. Ann Med. 2023 Dec;55(1):2197289. doi: 10.1080/07853890.2023.2197289. PMID: 37074264; PMCID: PMC10120558.
Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. Obstet Gynecol. 2020 Jun;135(6):e237-e260. doi: 10.1097/AOG.0000000000003891. PMID: 32443079.
Michalczyk M, Celewicz A, Celewicz M, Woźniakowska-Gondek P, Rzepka R. The Role of Inflammation in the Pathogenesis of Preeclampsia. Mediators Inflamm. 2020 Oct 5;2020:3864941. doi: 10.1155/2020/3864941. PMID: 33082708; PMCID: PMC7556088.
Lumbers ER, Delforce SJ, Arthurs AL, Pringle KG. Causes and Consequences of the Dysregulated Maternal Renin-Angiotensin System in Preeclampsia. Front Endocrinol (Lausanne). 2019 Sep 10;10:563. doi: 10.3389/fendo.2019.00563. PMID: 31551925; PMCID: PMC6746881.
Zuo Y, Kanthi Y, Knight JS, Kim AHJ. The interplay between neutrophils, complement, and microthrombi in COVID-19. Best Pract Res Clin Rheumatol. 2021 Mar;35(1):101661. doi: 10.1016/j.berh.2021.101661. Epub 2021 Jan 13. PMID: 33526325; PMCID: PMC7831864.
Narang K, Enninga EAL, Gunaratne MDSK, Ibirogba ER, Trad ATA, Elrefaei A, Theiler RN, Ruano R, Szymanski LM, Chakraborty R, Garovic VD. SARS-CoV-2 Infection and COVID-19 During Pregnancy: A Multidisciplinary Review. Mayo Clin Proc. 2020 Aug;95(8):1750-1765. doi: 10.1016/j.mayocp.2020.05.011. Epub 2020 May 30. PMID: 32753148; PMCID: PMC7260486.
Guida JP, Cecatti JG, Souza RT, Pacagnella RC, Ribeiro-do-Valle CC, Luz AG, Lajos GJ, Surita FG, Nobrega GM, Griggio TB, Charles CM, Miele MJ, Ferreira SB, Tedesco RP, Fernandes KG, Martins-Costa SHA, Ramos JGL, Peret FJA, Feitosa FE, Traina E, Cunha-Filho EV, Vettorazzi J, Haddad SM, Andreucci CB, Correa-Junior MD, Mayrink J, Dias MAB, Oliveira LG, Melo-Junior EF, da Luz MGQ, Costa ML; REBRACO Study Group. Preeclampsia among women with COVID-19 during pregnancy and its impact on maternal and perinatal outcomes: Results from a national multicenter study on COVID in Brazil, the REBRACO initiative. Pregnancy Hypertens. 2022 Jun;28:168-173. doi: 10.1016/j.preghy.2022.05.005. Epub 2022 May 10. PMID: 35568019; PMCID: PMC9085347.
Suresh S, Siddiqui M, Abu Ghanimeh M, Jou J, Simmer S, Mendiratta V, Russell S, Al-Shammari M, Chatfield A, Alsheik E, Dang D, Genaw J, Zuchelli T. Association of obesity with illness severity in hospitalized patients with COVID-19: A retrospective cohort study. Obes Res Clin Pract. 2021 Mar-Apr;15(2):172-176. doi: 10.1016/j.orcp.2021.02.006. Epub 2021 Feb 25. PMID: 33653666; PMCID: PMC7904471.
Tran M, Alessandrini V, Lepercq J, Goffinet F. Risk of preeclampsia in patients with symptomatic COVID-19 infection. J Gynecol Obstet Hum Reprod. 2022 Nov;51(9):102459. doi: 10.1016/j.jogoh.2022.102459. Epub 2022 Aug 15. PMID: 35981706; PMCID: PMC9376977.
Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, Roggero P, Prefumo F, do Vale MS, Cardona-Perez JA, Maiz N, Cetin I, Savasi V, Deruelle P, Easter SR, Sichitiu J, Soto Conti CP, Ernawati E, Mhatre M, Teji JS, Liu B, Capelli C, Oberto M, Salazar L, Gravett MG, Cavoretto PI, Nachinab VB, Galadanci H, Oros D, Ayede AI, Sentilhes L, Bako B, Savorani M, Cena H, García-May PK, Etuk S, Casale R, Abd-Elsalam S, Ikenoue S, Aminu MB, Vecciarelli C, Duro EA, Usman MA, John-Akinola Y, Nieto R, Ferrazi E, Bhutta ZA, Langer A, Kennedy SH, Papageorghiou AT. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr. 2021 Aug 1;175(8):817-826. doi: 10.1001/jamapediatrics.2021.1050. Erratum in: JAMA Pediatr. 2022 Jan 1;176(1):104. PMID: 33885740; PMCID: PMC8063132.
DuBose MB, Tembunde MY, Goodman KE, Pineles ML, Nadimpalli G, Baghdadi JD, Parchem JG, Harris AD, Pineles BL. Delivery Outcomes in a Cohort of Pregnant Patients with COVID-19 With and Without Viral Pneumonia. Am J Obstet Gynecol MFM. 2023 Jul 1:101077. doi: 10.1016/j.ajogmf.2023.101077. Epub ahead of print. PMID: 37399892.
Pineles BL, Goodman KE, Pineles L, O'Hara LM, Nadimpalli G, Magder LS, Baghdadi JD, Parchem JG, Harris AD. Pregnancy and the Risk of In-Hospital Coronavirus Disease 2019 (COVID-19) Mortality. Obstet Gynecol. 2022 May 1;139(5):846-854. doi: 10.1097/AOG.0000000000004744. Epub 2022 Apr 5. PMID: 35576343; PMCID: PMC9015030.
Allotey J, Stallings E, Bonet M, Yap M, Chatterjee S, Kew T, Debenham L, Llavall AC, Dixit A, Zhou D, Balaji R, Lee SI, Qiu X, Yuan M, Coomar D, Sheikh J, Lawson H, Ansari K, van Wely M, van Leeuwen E, Kostova E, Kunst H, Khalil A, Tiberi S, Brizuela V, Broutet N, Kara E, Kim CR, Thorson A, Oladapo OT, Mofenson L, Zamora J, Thangaratinam S; for PregCOV-19 Living Systematic Review Consortium. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ. 2020 Sep 1;370:m3320. doi: 10.1136/bmj.m3320. Update in: BMJ. 2022 May 30;377:o1205. PMID: 32873575; PMCID: PMC7459193.
Antoun L, Taweel NE, Ahmed I, Patni S, Honest H. Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study. Eur J Obstet Gynecol Reprod Biol. 2020 Sep;252:559-562. doi: 10.1016/j.ejogrb.2020.07.008. Epub 2020 Jul 15. PMID: 32732059; PMCID: PMC7362841.
Bourne T, Kyriacou C, Coomarasamy A, Al-Memar M, Leonardi M, Kirk E, Landolfo C, Blanchette-Porter M, Small R, Condous G, Timmerman D. ISUOG Consensus Statement on rationalization of early-pregnancy care and provision of ultrasonography in context of SARS-CoV-2. Ultrasound Obstet Gynecol. 2020 Jun;55(6):871-878. doi: 10.1002/uog.22046. PMID: 32267981; PMCID: PMC7262213.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Anna Kozłowska, Anna Korzeniowska, Karolina Gendek, Ilona Gąbka, Weronika Dalmata, Jan Dąbrowski, Ewelina Zygmunt-Siembida, Dariusz Chojęta
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 360
Number of citations: 0