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Journal of Education, Health and Sport

Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature
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  • Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature
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  4. Review Articles

Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature

Authors

  • Aleksandra Nowak Szpital Specjalistyczny im SZ Starkiewicza w Dąbrowie Górniczej https://orcid.org/0009-0006-8572-8798
  • Alicja Nowak th Navy Hospital in Gdańsk, Polanki 117, 80-305 Gdansk, Poland https://orcid.org/0009-0000-4684-2877
  • Klaudia Bogusz 7th Navy Hospital in Gdańsk, Polanki 117, 80-305 Gdansk, Poland https://orcid.org/0009-0008-0818-2423
  • Łucja Cywka 7th Navy Hospital in Gdańsk, Polanki 117, 80-305 Gdansk, Poland https://orcid.org/0009-0007-8314-4825
  • Natalia Baran Independent Public Clinical Hospital of the prof W. Orlowski in Warsaw, Czerniakowska 231, 00-416 Warsaw, Poland https://orcid.org/0000-0002-3221-9651
  • Adriana Bielak The Brothers Hospitallers of Saint John of God Hospital, Trynitarska 11, 31-061 Krakow, Poland https://orcid.org/0009-0000-4998-0458
  • Weronika Szwed Provincial Specialist Hospital in Olsztyn, Żołnierska 18, 10-561 Olsztyn, Poland https://orcid.org/0000-0001-9546-7970
  • Marcela Maksymowicz Independent Public Clinical Hospital No. 4 in Lublin, Jaczewskiego 8, 20-954 Lublin, Poland https://orcid.org/0000-0003-2611-1609
  • Piotr Machowiec Independent Public Clinical Hospital No. 4 in Lublin, Jaczewskiego 8, 20-954 Lublin, Poland https://orcid.org/0000-0002-5418-0110

DOI:

https://doi.org/10.12775/JEHS.2023.21.01.011

Keywords

fractional micro-needle radiofrequency, side effects, mechanism of action, safety, effectiveness, treatment, Morpheus8

Abstract

Introduction and purpose: 

For all skin types, micro-needle radiofrequency (FMR) can be a safe and effective aesthetic medicine procedure for the treatment of various dermatological and aesthetic conditions. The aim of the study is to present the mechanism of action and assess safety, treatment efficacy, and possible side effects on the basis of a review of the scientific literature. 

Description of the state of knowledge: 

FMR uses micro-needles to penetrate the skin to a depth of up to 4.5 mm and deliver radiofrequency current in a fractional manner, producing the controlled fractions of micro-injuries in the dermis, inducing neocollagenesis, neoelastinogenesis, and angiogenesis. FMR has a wide range of positive effects such as skin rejuvenation, skin tightening, facial and body scar remodeling, and hair growth through transdermal collagen induction. 

Summary: 

Increasingly, patients are looking for minimally invasive methods of skin tightening and fat remodeling. In response, Aesthetic Medicine has proposed a combination of two techniques, micro-needling and radiofrequency. As more and more studies are showing the effectiveness and efficiency of this procedure, also emphasizing its safety, minimal risk of serious side effects, and ease of use, micro-needle radiofrequency is being proposed as an attractive answer to people's desires for a less invasive method of skin rejuvenation. However, further research in this area is needed to optimize the parameters of the treatment to achieve the best results.

References

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Juhasz, M. L. W., & Cohen, J. L. (2020). Microneedling for the Treatment of Scars: An Update for Clinicians. Clinical, cosmetic and investigational dermatology, 13, 997–1003. https://doi.org/10.2147/CCID.S267192

Austin, G. K., Struble, S. L., & Quatela, V. C. (2022). Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review. Lasers in surgery and medicine, 54(1), 27–45. https://doi.org/10.1002/lsm.23506

Jung, J. M., Na, H. M., Kim, J. H., Yoon, J., Yang, H. J., Lee, W. J., Chang, S. E., Lee, M. W., & Won, C. H. (2022). The efficacy and safety of a fractional microneedle radiofrequency device for the treatment of axillary hyperhidrosis: clinical prospective pilot study. Lasers in medical science, 37(3), 1559–1566. https://doi.org/10.1007/s10103-021-03404-z

Kreindel, M., & Mulholland, S. (2022). The Basic Science of Radiofrequency-Based Devices. IntechOpen. doi: 10.5772/intechopen.96652

Dayan, E., Chia, C., Burns, A. J., & Theodorou, S. (2019). Adjustable Depth Fractional Radiofrequency Combined With Bipolar Radiofrequency: A Minimally Invasive Combination Treatment for Skin Laxity. Aesthetic surgery journal, 39(Suppl_3), S112–S119. https://doi.org/10.1093/asj/sjz055

Dayan, E., Burns, A. J., Rohrich, R. J., & Theodorou, S. (2020). The Use of Radiofrequency in Aesthetic Surgery. Plastic and reconstructive surgery. Global open, 8(8), e2861. https://doi.org/10.1097/GOX.0000000000002861

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Sasaki G. H. (2017). Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns. Aesthetic surgery journal, 37(1), 71–83. https://doi.org/10.1093/asj/sjw120

El-Domyati M, Barakat M, Awad S, Medhat W, El-Fakahany H, Farag H. Microneedling Therapy for Atrophic Acne Scars: An Objective Evaluation. J Clin Aesthet Dermatol. 2015 Jul;8(7):36-42. PMID: 26203319; PMCID: PMC4509584.

Bhargava, S., Kumar, U., & Varma, K. (2019). Subcision and Microneedling as an Inexpensive and Safe Combination to Treat Atrophic Acne Scars in Dark Skin: A Prospective Study of 45 Patients at a Tertiary Care Center. The Journal of clinical and aesthetic dermatology, 12(8), 18–22.

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Yadav, S., & Dogra, S. (2016). A Cutaneous Reaction to Microneedling for Postacne Scarring Caused by Nickel Hypersensitivity. Aesthetic surgery journal, 36(4), NP168–NP170. https://doi.org/10.1093/asj/sjv229

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Alexiades-Armenakas, M., Rosenberg, D., Renton, B., Dover, J., & Arndt, K. (2010). Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity. Archives of dermatology, 146(4), 396–405. https://doi.org/10.1001/archdermatol.2010.24

el-Domyati, M., el-Ammawi, T. S., Medhat, W., Moawad, O., Brennan, D., Mahoney, M. G., & Uitto, J. (2011). Radiofrequency facial rejuvenation: evidence-based effect. Journal of the American Academy of Dermatology, 64(3), 524–535. https://doi.org/10.1016/j.jaad.2010.06.045

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Doddaballapur S. (2009). Microneedling with dermaroller. Journal of cutaneous and aesthetic surgery, 2(2), 110–111. https://doi.org/10.4103/0974-2077.58529

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Published

2023-07-25

How to Cite

1.
NOWAK, Aleksandra, NOWAK, Alicja, BOGUSZ, Klaudia, CYWKA, Łucja, BARAN, Natalia, BIELAK, Adriana, SZWED, Weronika, MAKSYMOWICZ, Marcela and MACHOWIEC, Piotr. Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature. Journal of Education, Health and Sport. Online. 25 July 2023. Vol. 21, no. 1, pp. 106-114. [Accessed 9 May 2025]. DOI 10.12775/JEHS.2023.21.01.011.
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Vol. 21 No. 1 (2023)

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Review Articles

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Copyright (c) 2023 Aleksandra Nowak, Alicja Nowak, Klaudia Bogusz, Łucja Cywka, Natalia Baran, Adriana Bielak, Weronika Szwed, Marcela Maksymowicz, Piotr Machowiec

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