Erythema infectious and its significance in pregnancy - analysis of knowledge among women
DOI:
https://doi.org/10.12775/JEHS.2023.14.01.011Keywords
erythema infectious, parvovirus B19, five disease, pregnancy, fetal hydrops, anemiaAbstract
Introduced: Erythema infectious disease is a childhood infectious disease associated with a rash caused by parvovirus B19. The infection is especially dangerous for pregnant women. The disease can lead to intrauterine anemia and miscarriage, even when the pregnant woman did not have any clinical signs of infection.
Aim of the study: The aim of the study was to assess the level of women's knowledge about erythema infectious and its importance in pregnancy.
Materials and methods: The study conducted in May 2023 covered 150 women in various age groups. The research material was collected using an anonymous online questionnaire. The obtained results were analyzed and verified on the basis of scientific literature.
Results: The percentage of respondents who had contact with erythema infectious is 64.7% and 64% correctly indicated parvovirus B19 as the etiological factor of the disease. 78% of respondents know that infection with erythema infectious is dangerous for pregnant women. 51.3% of respondents confirm that parvovirus B19 can cause fetal hydrops and 61.3% of women clearly indicate that even an asymptomatic course of infection in pregnant women can be a threat to the fetus.
Conclusions: Women have basic knowledge about erythema infectious and its negative impact on pregnancy, but do not know details about complications and treatment. Women should be educated about the risk factors for the disease its symptoms and the effects of the disease. The aim is to minimize the risk of infection during pregnancy.
References
de Los Ángeles Ribas M, Tejero Y, Cordero Y, Pérez D, Sausy A, Muller CP, Hübschen JM. Identification of human parvovirus B19 among measles and rubella suspected patients from Cuba. J Med Virol. 2019 Jul;91(7):1351-1354.doi: 10.1002/jmv.25444.PMID: 30817853.
Heegaard ED, Brown KE. Human parvovirus B19. Clin Microbiol Rev. 2002;15(3):485–505. doi: 10.1128/CMR.15.3.485-505.2002.PMID: 12097253 PMCID: PMC118081
Staroselsky A, Klieger-Grossmann C, Garcia-Bournissen F, Koren G. Exposure to fifth disease in pregnancy. Can Fam Physician. 2009 Dec; 55(12): 1195–1198. PMID:20008596; PMCID:PMC2793222.
Ornoy A, Ergaz Z. Parvovirus B19 infection during pregnancy and risks to the fetus. Birth Defects Res 2017 Mar 15;109(5):311-323. doi: 10.1002/bdra.23588.PMID: 28398685.
Weigel-Kelley KA, Yoder MC, Srivastava A. Recombinant human parvovirus B19vectors: erythrocyte P antigen is necessary but not sufficient for successful transduction of human hematopoietic cells. J Virol 2001;75:4110–16.doi: 10.1128/JVI.75.9.4110-4116.2001.PMCID: PMC114156PMID: 11287560.
Ergaz Z, Ornoy A. Parvovirus B19 in pregnancy. Reprod Toxicol. 2006;21(4):421–35. doi: 10.1016/j.reprotox.2005.01.006.PMID: 16580942
Servey JT, Reamy BV, Hodge J. Clinical presentations of parvovirus B19 infection. Am Fam Physician. 2007;75(3):373–6.PMID: 17304869
Allmon A, Deane K, Martin KL. Common Skin Rashes in Children. Am Fam Physician. 2015 Aug 01;92(3):211-6.PMID: 26280141
Kostolansky S,Waymack JR. Erythema Infectiosum. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.2022 Oct 30.PMID: 30020681 Bookshelf ID: NBK513309
Feldman DM, Timms D, Borgida AF. Toxoplasmosis, parvovirus, and cytomegalovirus in pregnancy.Clin Lab Med. 2010 Sep;30(3):709-20. doi: 10.1016/j.cll.2010.04.009. Epub 2010 Jun 15.PMID: 20638583.
Barlinn, R, Trogstad L, Rollag, H, Frøen, F, Magnus P, Dudman, SG. Parvovirus B19 DNAemia in pregnant women in relation to perinatal death: A nested case-control study within a large population-based pregnancy cohort. Acta Obstet. Gynecol. Scand. 2020, 99, 856–864. PMID: 31925774 DOI: 10.1111/aogs.13801
Grubman O, Hussain FN, Nelson Z, Brustman, L. Maternal parvovirus B19 infection causing first-trimester increased nuchal translucency and fetal hydrops. Case Rep. Obstet. Gynecol. 2019, 2019, 3259760. doi: 10.1155/2019/3259760. eCollection 2019. PMID: 31360565. PMCID: PMC6642751.
Waring GJ. Parvovirus B19 infection: Timely diagnosis in pregnancy essential. Womens Health. 2018 Apr; 18: e00057. doi: 10.1155/2019/3259760. PMCID:PMC5960029. PMID: 29785387.
Mirambo MM, Maliki F, Majigo M, Mushi MF, Moremi N, Seni J, Matovelo D, Mshana SE.The magnitude and correlates of Parvovirus B19 infection among pregnant women attending antenatal clinics in Mwanza, Tanzania. BMC Pregnancy Childbirth 2017, 17, 176. doi: 10.1186/s12884-017-1364-y.PMID: 28592274 PMCID: PMC5463315.
Giorgio E, De Oronzo, MA, Iozza I, Di Natale A., Cianci S, Garofalo G. Giacobbe, AM., Politi S. Parvovirus B19 during pregnancy: A review. J. Prenat. Med. 2010, 4, 63–66. PMCID: PMC3279187. PMID: 22439064.
Attwood LO, Holmes NE, Hui L. Identification and management of congenital parvovirus B19 infection. Prenat. Diagn. 2020, 40, 1722–1731. doi: 10.1002/pd.5819. PMID: 32860469.
De Jong EP, de Haan TR, Kroes AC, Beersma MF, Oepkes D, Walther FJ. Parvovirus B19 infection in pregnancy. J Clin Virol. 20 Feb 2006, 36(1):1-7.Corrected: 2007 Feb;38(2):188. DOI: 10.1016/j.jcv.2006.01.004 PMID: 16488187
Kontomanolis EN, Fasoulakis Z. Hydrops Fetalis and THE Parvovirus B-19. Curr Pediatr Rev. 2018;14(4):239-252.DOI:10.2174/1573396314666180820154340 PMID: 30124157
Kostolansky S, Waymack J. R.Erythema Infectiosum.In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.2022 Oct 30.PMID: 30020681 Bookshelf ID: NBK513309
Macri A, Crane JS. Parvoviruses. Copyright 2023, StatPearls Publishing LLC.Bookshelf ID: NBK482245 PMID: 29489222
Kielaite D, Paliulyte V. Parvovirus (B19) Infection during Pregnancy: Possible Effect on the Course of Pregnancy and Rare Fetal Outcomes. A Case Report and Literature Review.Medicina (Kaunas). 2022 May; 58(5): 664. Published online 2022 May 15. doi: 10.3390/medicina58050664.PMCID:PMC9144227. PMID: 35630081
Auriti C, De Rose DU, Santisi A, Martini L, Piersigilli F, Bersani I, Ronchetti MP, Caforio L. Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 and Zika virus. Biochim. Biophys. Acta Mol. Basis Dis. 2021, 1867, 166198.doi: 10.1016/j.bbadis.2021.166198. Epub 2021 Jun 10.PMID: 34118406 PMCID: PMC8883330
Lamont RF, Sobel JD, Kusanovic JP, Mazaki-Tovi S, Kim SK, Uldbjerg N, Romero R.Parvovirus B10 infection in human pregnancy. BJOG, 2011;118:175-186.doi: 10.1111/j.1471-0528.2010.02749.x. Epub 2010 Oct 13.PMID: 21040396 PMCID: PMC3059196.
Curcio AM, Shekhawat P, Reynolds AS, Thakur KT. Neurologic infections during pregnancy. In Handbook of Clinical Neurology; Elsevier: Amsterdam, The Netherlands, 2020; Volume 172, pp. 79–104. doi: 10.1016/B978-0-444-64240-0.00005-2.PMID: 32768096 PMCID: PMC7402657.
De Vries LS. Viral infections and the neonatal brain. Semin. Pediatr. Neurol. 2019, 32, 100769.doi: 10.1016/j.spen.2019.08.005. Epub 2019 Aug 7.PMID: 31813517
Jindal A, Sharma M, Zalak V, Chaudhary C. Amniocentesis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.2022 Sep 9.PMID: 32644673 Bookshelf ID: NBK559247.
Roberts D, Brown J, Medley N, Dalziel SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst. Rev. 2017, 3, CD004454.doi: 10.1002/14651858.CD004454.pub3.PMID: 28321847 PMCID:PMC6464568.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Agnieszka Socha, Kinga Musz, Katarzyna Dobko, Gabriela Frącz, Agata Glac, Klaudia Kuliga, Natalia Sejnowska, Agata Surowiec, Kinga Śnieżek, Anna Zając
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 1118
Number of citations: 0