Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

Neuropathy and neuroarthropathy as a complication of diabetes and other diseases, with particular emphasis on painless fractures - a review of the literature
  • Home
  • /
  • Neuropathy and neuroarthropathy as a complication of diabetes and other diseases, with particular emphasis on painless fractures - a review of the literature
  1. Home /
  2. Archives /
  3. Vol. 25 No. 1 (2023) /
  4. Review Articles

Neuropathy and neuroarthropathy as a complication of diabetes and other diseases, with particular emphasis on painless fractures - a review of the literature

Authors

  • Michal Oleszko Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, al. mjr. W. Kopisto 2a, 35-959 Rzeszów https://orcid.org/0000-0002-2635-0856
  • Kamila Fularska CENTRUM MEDYCZNE W ŁAŃCUCIE SP. Z O.O. ul. Paderewskiego 5, 37-100 Łańcut https://orcid.org/0000-0002-1338-3982
  • Aleksandra Kuźniar Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, al. mjr. W. Kopisto 2a, 35-959 Rzeszów https://orcid.org/0009-0007-8759-2633
  • Dominik Szawica Szpital św. Michała Archanioła - Centrum Medyczne w Łańcucie https://orcid.org/0009-0004-7089-9266
  • Edward Wąsiewicz CENTRUM MEDYCZNE W ŁAŃCUCIE SP. Z O.O. ul. Paderewskiego 5, 37-100 Łańcut https://orcid.org/0000-0002-0339-6202
  • Radosław Bernacki Uniwersytet Medyczny w Lublinie Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0009-0000-1554-2724
  • Piotr Bernacki Uniwersytet Medyczny w Lublinie Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0009-0002-9324-9632
  • Martyna Dutka Uniwersytet Medyczny w Lublinie Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0009-0006-4747-677X
  • Witold Zardzewiały Uniwersytet Medyczny w Lublinie Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0000-0003-4459-0535

DOI:

https://doi.org/10.12775/JEHS.2023.25.01.007

Keywords

Neuropathy, Neuroarthopathy, Diabetes, Fractures

Abstract

Diabetes is now one of the most common chronic diseases. Its incidence is increasing, and thus the number of people suffering from its health complications is increasing. In 2015, 3 million people in Poland suffered from diabetes, and it is estimated that this number will increase to 4 million by 2040.

Acute complications of diabetes include i.a. hypoglycemic or lactate and hypermolar comas. Chronic complications include, for example, microangiopathies (retinopathies, nephropathy) as well as macroangiopathies and neuropathies.

Neuropathy is the result of too much glycemia and can affect as many as 2/3 of diabetic patients. Everyday pain sometimes makes it impossible to perform the simplest activities, and an optimal treatment plan is difficult to develop. At the same time, it can be prevented with regular exercise, regular glycemic control and a proper diet.

In this paper, we present a literature review on neuropathy and neuroarthropathy as a complication of diabetes and other diseases, with particular emphasis on painless fractures.

References

Sebastian Szczyrba, Grzegorz Kozera, Leszek Bieniaszewski, Walenty M. Nyka. Neuropatia cukrzycowa — patogeneza, rozpoznawanie, zapobieganie, leczenie, Forum Medycyny Rodzinnej 2010, tom 4, nr 5, 339–355

Witold Paweł Kalbarczyk, prof. dr hab. med. Bogusław Okopień. Raport Instytutu Ochrony Zdrowia - Cukrzyca. Gdzie jesteśmy? Dokąd zmierzamy? 2018

James C. Watson, MD, and P. James B. Dyck, MD. Peripheral Neuropathy: A Practical Approach to Diagnosis and Symptom Management. July 2015;90(7):940-951 Mayo Clin Proc.

Kumar V, Abbas AK , Aster J (2017) Basic Pathology 10th edition, Elsevier, Chicago

Gill G, Benbow S, Tesfaye S, Kaczmarczyk E, Kaye L, 1993, et al Painless stress fractures in diabetic neuropathic feet. Postgraduate Medical Journal 73:241-242. http://dx.doi.org/10.1136/pgmj.73.858.241

Galanopoulos I P, Stavlas P, Voyaki S M, et al. (February 23, 2021) Ankle Fractures in Diabetic Patients: Report of Two Cases. Cureus 13(2): e13519. doi:10.7759/cureus.13519

Gouveri E, Papanas N. Charcot osteoarthropathy in diabetes: A brief review with an emphasis on clinical practice (2011) World J Diabetes. 2(5):59-65. doi:10.4239/wjd.v2.i5.59

Levitt BA, Stapleton JJ, Zgonis T. Diabetic Lisfranc fracture-dislocations and Charcot neuroarthropathy. (2013) Clin Podiatr Med Surg.30(2):257-63. doi: 10.1016/j.cpm.2013.01.002.

Diabetes Control and Complications Trial (DCCT): results of feasibility study. The DCCT Research Group. Diabetes Care. 1987 Jan-Feb;10(1):1-19. doi: 10.2337/diacare.10.1.1. PMID: 2882967.

Singh N, Armstrong DG & Lipsky BA Preventing Foot Ulcers in Patients With Diabetes. JAMA 293, 217–228, doi: 10.1001/jama.293.2.217 (2005). [PubMed] [CrossRef] [Google Scholar]

Most RS & Sinnock P The Epidemiology of Lower Extremity Amputations in Diabetic Individuals. Diabetes Care 6, 87–91, doi: 10.2337/diacare.6.1.87 (1983). [PubMed] [CrossRef] [Google Scholar]

Young MJ, Boulton AJM, Macleod AF, Williams DRR & Sonksen PH A multicentre study of the prevalence of diabetic peripheral neuropathy in the United Kingdom hospital clinic population. Diabetologia 36, 150–154, doi: 10.1007/BF00400697 (1993). [PubMed] [CrossRef] [Google Scholar]

. Maser RE et al. Epidemiological Correlates of Diabetic Neuropathy: Report From Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes 38, 1456–1461, doi: 10.2337/diab.38.11.1456 (1989). [PubMed] [CrossRef] [Google Scholar]

Cole JB, Florez JC. Genetics of diabetes mellitus and diabetes complications. Nat Rev Nephrol. 2020 Jul;16(7):377-390. doi: 10.1038/s41581-020-0278-5. Epub 2020 May 12. PMID: 32398868; PMCID: PMC9639302.

Diabetes Control and Complications Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977–986 [PubMed] [Google Scholar]

Diabetes Control and Complications Research Group Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial. Ann Neurol 1995;38:869–880 [PubMed] [Google Scholar]

Linn T, Ortac K, Laube H, Federlin K. Intensive therapy in adult insulin-dependent diabetes mellitus is associated with improved insulin sensitivity and reserve: a randomized, controlled, prospective study over 5 years in newly diagnosed patients. Metabolism 1996;45:1508–1513 [PubMed] [Google Scholar]

Callaghan BC, Cheng HT, Stables CL, Smith AL, Feldman EL. Diabetic neuropathy: clinical manifestations and current treatments. Lancet Neurol 2012;11:521–534 [PMC free article] [PubMed] [Google Scholar]

Pop-Busui R, Boulton AJ, Feldman EL, Bril V, Freeman R, Malik RA, Sosenko JM, Ziegler D. Diabetic Neuropathy: A Position Statement by the American Diabetes Association. Diabetes Care. 2017 Jan;40(1):136-154. doi: 10.2337/dc16-2042. PMID: 27999003; PMCID: PMC6977405.

Ohkubo Y, Kishikawa H, Araki E, et al.. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract 1995;28:103–117 [PubMed] [Google Scholar]

Ismail-Beigi F, Craven T, Banerji MA, et al..; ACCORD trial group . Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 2010;376:419–430 [PMC free article] [PubMed] [Google Scholar]

Gaede P, Vedel P, Larsen N, Jensen GV, Parving HH, Pedersen O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 2003;348:383–393 [PubMed] [Google Scholar]

Knowler WC, Barrett-Connor E, Fowler SE, et al..; Diabetes Prevention Program Research Group . Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393–403 [PMC free article] [PubMed] [Google Scholar]

Balducci S, Iacobellis G, Parisi L, et al.. Exercise training can modify the natural history of diabetic peripheral neuropathy. J Diabetes Complications 2006;20:216–223 [PubMed] [Google Scholar]

Singleton JR, Marcus RL, Jackson JE, K Lessard M, Graham TE, Smith AG. Exercise increases cutaneous nerve density in diabetic patients without neuropathy. Ann Clin Transl Neurol 2014;1:844–849 [PMC free article] [PubMed] [Google Scholar]

Kluding PM, Pasnoor M, Singh R, et al. The effect of exercise on neuropathic symptoms, nerve function, and cutaneous innervation in people with diabetic peripheral neuropathy. J Diabetes Complications. 2012;26:424–429. [PMC free article] [PubMed] [Google Scholar]

Smith AG, Russell J, Feldman EL, et al. Lifestyle intervention for pre-diabetic neuropathy. Diabetes Care. 2006;29:1294–1299. [PubMed] [Google Scholar]

Reading AD, Stother IG. The painless fracture: could it be TB? J R Coll Surg Edinb. 1998 Dec;43(6):410-1. PMID: 9990791.

Holmøy T, Sandberg L. Lårhalsbrudd uten smerter ved multippel sklerose [Painless femoral neck fracture in a patient with multiple sclerosis]. Tidsskr Nor Laegeforen. 1996 Jan 20;116(2):249. Norwegian. PMID: 8633335.

Lovy AJ, Dowdell J, Keswani A, et al. Nonoperative Versus Operative Treatment of Displaced Ankle Fractures in Diabetics. Foot & Ankle International. 2017;38(3):255-260. doi:10.1177/1071100716678796

Ramlatchan SR, Pomerantz LH, Ganti L, Lee WK, Delk GT. Phalangeal Fracture Secondary to Hammering One's Finger. Cureus. 2020 Jul 21;12(7):e9313. doi: 10.7759/cureus.9313. PMID: 32839682; PMCID: PMC7440264.

Singh J, Jain K, Mruthyunjaya, Ravishankar R. Outcome of closed proximal phalangeal fractures of the hand. Indian J Orthop. 2011 Sep;45(5):432-8. doi: 10.4103/0019-5413.83764. PMID: 21886925; PMCID: PMC3162680.

Oleszko, M., Wąsiewicz, E., Fularska, K., Kuźniar, A. and Szawica, D. 2023. A painless fracture of a phalanx of the left hand in a patient with type 1 diabetes – case report. Journal of Education, Health and Sport. 17, 1 (Mar. 2023), 46–50. DOI:https://doi.org/10.12775/JEHS.2023.17.01.005.

Downloads

  • PDF

Published

2023-05-03

How to Cite

1.
OLESZKO, Michal, FULARSKA, Kamila, KUŹNIAR, Aleksandra, SZAWICA, Dominik, WĄSIEWICZ, Edward, BERNACKI, Radosław, BERNACKI, Piotr, DUTKA, Martyna and ZARDZEWIAŁY, Witold. Neuropathy and neuroarthropathy as a complication of diabetes and other diseases, with particular emphasis on painless fractures - a review of the literature. Journal of Education, Health and Sport. Online. 3 May 2023. Vol. 25, no. 1, pp. 75-82. [Accessed 6 July 2025]. DOI 10.12775/JEHS.2023.25.01.007.
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 25 No. 1 (2023)

Section

Review Articles

License

Copyright (c) 2023 Michal Oleszko, Kamila Fularska, Aleksandra Kuźniar, Dominik Szawica, Edward Wąsiewicz, Radosław Bernacki, Piotr Bernacki, Martyna Dutka, Witold Zardzewiały

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 1054
Number of citations: 0

Search

Search

Browse

  • Browse Author Index
  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

Neuropathy, Neuroarthopathy, Diabetes, Fractures
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop