Concise compilation of the most clinically relevant current knowledge on Brugada Syndrome
DOI:
https://doi.org/10.12775/JEHS.2023.25.01.001Keywords
Brugada syndrome, channelopathies, cardiac arrhythmias, sudden cardiac death (SCD)Abstract
Brugada syndrome (BrS) is a rare disease in which arrhythmogenic changes occur in patients without any structural heart pathology. Its most dangerous complication is sudden cardiac arrest, which most often occurs around the 3rd and 4th decade of life of patients. In a similar period of time (20 - 40 years of age), the first clinical manifestations of the disease also most often occur, although this can happen even sooner in the case of a malignant form of the disease. Brugada syndrome is significantly (about 8 times) more frequently diagnosed in men, and the main factors that strongly worsen its prognosis are incidents of syncope noted in the patient's history and observed spontaneous changes in ECG studies [1][2].
References
Grzegorz K. Jakubiak. Zespół Brugadów etiopatogeneza, diagnostyka i leczenie. [Brugada syndrome – etiopathogenesis, diagnosis and treatment]. W: Kardiologia. VOL 23/NR 04/2016 (248): 42-48.
Sierosławska, Agata, Joanna Szklarczyk, Katarzyna Nawrot-Porąbka. Zespół Brugadów – postępowanie diagnostyczno-terapeutyczne w oparciu o analizę przypadku. [Brugada syndrome - diagnostic and therapeutic procedures - case study]. UJK/WNOZ. APD / O. diploma-103791-162768. Polish.
Marina Cerrone, Sarah Costa, Mario Delmar. The Genetics of Brugada Syndrome. W: Annual Review of Genomics and Human Genetics. 2022. 23:255–74.
Paweł Maciński, Andrzej Osiecki, Małgorzata Oleszczak-Kostyra, Wacław Kochman. Zespół Brugadów — rzadkie schorzenie, więc zachowaj czujność!. [Brugada syndrome: rare so, beware! ]. W: Via Medica. Folia Cardiologica 2022 vol. 17, no. 2: 123–126. ISSN 2353–7752.
Aneta Kucharczyk-Foltyn , Maria Śnieżek-Maciejewska , Maciej Dymek , Jerzy Sadowski i Marianna Janion. Zespół Brugadów — od rozpoznania do leczenia. [Brugada syndrome - from diagnosis to treatment]. W: Via Medica. Folia Cardiologica Excerpta 2008, tom 3, nr 1: 21–28. ISSN 1896–2475
Piotr Kukla , Sebastian Stec , Monika Kukla , Kazimierz Szczuka. Bezobjawowy zespół Brugadów – problemy diagnostyczne. [Asymptomatic Brugada sign – diagnostic dilemma]. Elektrokardiogram miesiąca/Electrocardiogram of the month. Kardiol Pol 2006; 64: 1303-1307. Polish.
Giuseppe Mascia, Roberta Della Bona, Pietro Ameri, Marco Canepa, Italo Porto, Gianfranco Parati, Lia Crotti, Michele Brignole. Brugada syndrome and syncope: a practical approach for diagnosis and treatment. EP Europace, Volume 23, Issue 7, 2021: 996–1002.
Jitendra Vohra, Sulekha Rajagopalan. Update on the Diagnosis and Management of Brugada Syndrome. Heart, Lung and Circulation. Volume 24, Issue 12. 2015: 1141-1148. ISSN 1443-9506.
https://commons.wikimedia.org/wiki/File:Brugada.jpg (dostęp: 2023.03.08).
Dąbek J., Lepich T. , Piechota M. Współczesny obraz zespołu Brugadów. [Recent clinical picture of Brugada syndrome]. Pol. Merk. Lek., 2011, XXXI, 186: 364-367. Polish.
Jonathan R. Skinner, Annika Winbo, Dominic Abrams, Jitendra Vohra, Arthur A. Wilde. Channelopathies That Lead to Sudden Cardiac Death: Clinical and Genetic Aspects. W: Heart, Lung and Circulation. Volume 28, Issue 1. 2019: 22-30. ISSN 1443-9506.
Andrés Ricardo Pérez Riera , Li Zhang , Augusto Hiroshi Uchida , Edgardo Schapachnik , Sergio Dubner i Celso Ferreira. Aktualne sposoby leczenia zaburzeń rytmu u pacjentów z zespołem Brugadów. [Current treatments for rhythm disturbances in patients with Brugada syndrome]. W: Via Medica. Folia Cardiologica Excerpta 2007, tom 2, nr 4; 138–147. ISSN 1896–2475. Polish.
Gumpanart Veerakul, Apichai Khongphatthanayothin, Koonlawee Nademanee. Brugada syndrome in Thailand: Three decades of progress. Heart Rhythm O2 2022;3:743–751.
Yukiko Nakano, Wataru Shimizu. Brugada Syndrome as a Major Cause of Sudden Cardiac Death in Asians. JACC: ASIA, VOL. 2, NO. 4, 2022: 412 – 421.
Aleksandra Miszczak , Marcin Rosiak , Michał Chudzik , Jerzy K. Wranicz. Burza elektryczna u pacjentów z kardiowerterem–defibrylatorem (ICD) — możliwości, zasady postępowania, perspektywy na przyszłość. [Electrical storm in cardioverter-defibrillator (ICD) patients - options, management principles, future prospects]. W: Via Medica. Folia Cardiologica Excerpta 2013, tom 8, nr ; 30–36. Polish.
Rizzo Alessandro, de Asmundis Carlo, Brugada Pedro, La Meir Mark, Chierchia Gian-Battista. Ablation for the treatment of Brugada syndrome: current status and future prospects.W: Expert Review of Medical Devices. Volume 17, 2020 - Issue 2: 123-130.
Ronpichai Chokesuwattanaskul1, Koonlawee Nademanee. Role of Catheter Ablation for Ventricular Arrhythmias in Brugada Syndrome. Curr Cardiol Rep (2021) 23: 54.
Nijak A, Saenen J, Labro AJ, Schepers D, Loeys BL, Alaerts M. iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives. International Journal of Molecular Sciences. 2021; 22(6):2825.
E Madelief J Marsman, Pieter G Postema, Carol Ann Remme. Brugada syndrome: update and future perspectives. Heart 2022;108:668-675.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Philip Kłakowicz, Monika Kuc, Aleksandra Kułakowska, Bartłomiej Lepczyński, Sebastian Lechowski
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 448
Number of citations: 0
