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Journal of Education, Health and Sport

Dietary Therapies in Pediatric Crohn’s Disease
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Dietary Therapies in Pediatric Crohn’s Disease

Authors

  • Izabela Kamińska Szpital Czerniakowski sp. z o. o., ul. Stępińska 19/25, 00-739 Warszawa https://orcid.org/0000-0002-5766-2262
  • Weronika Pawłocik Wojewódzki Szpital Zespolony w Lesznie, ul. Jana Kiepury 45, 64-115 Leszno https://orcid.org/0000-0001-7439-0820
  • Weronika Pawlak Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych i Administracji w Poznaniu im. prof. Ludwika Bierkowskiego, ul. Dojazd 34, 60-631 Poznań https://orcid.org/0000-0002-6016-1119
  • Ewa Grabowska Nowodworskie Centrum Medyczne, ul. Miodowa 2, 05-100 Nowy Dwór Mazowiecki https://orcid.org/0000-0003-1426-5205
  • Julia Szymańska Szpital Miejski im. Franciszka Raszei, ul.Mickiewicza 2, 60-834 Poznań https://orcid.org/0000-0001-6113-5046
  • Laura Wojtala Uniwersytecki Szpital Kliniczny w Poznaniu, ul.Przybyszewskiego 49, 60-355 Poznań https://orcid.org/0000-0002-5715-2334
  • Anna Rymarz Szpital MSWiA w Lublinie, ul.Grenadierów 3, 20-331 Lublin https://orcid.org/0000-0003-3387-1569
  • Dominika Kojder Samodzielny Publiczny Zakład Opieki Zdrowotnej w Przeworsku, ul. Szpitalna 16, 37-200 Przeworsk https://orcid.org/0000-0002-8915-4959
  • Małgorzata Piekarska Wojewódzki Szpital Specjalistyczny im.Stefana Kardynała Wyszyńskiego SPZOZ w Lublinie, al. Kraśnicka 100, 20-718 Lublin https://orcid.org/0000-0001-5055-4923
  • Klaudia Jedlina Centralny Szpital Kliniczny MSWiA w Warszawie, ul. Wołoska 137, 02-507 Warszawa https://orcid.org/0000-0002-2363-2620

DOI:

https://doi.org/10.12775/JEHS.2023.21.01.005

Keywords

crohn’s disease, dietary therapy, pediatrics, exclusion diets, nutritional treatment

Abstract

Introduction and Purpose: Crons’ disease is a chronic illness of the digestive system. Its etiology is multifactorial and one of the factors is nutrition. That is why the researchers are trying to labour the valuable types of dietary therapy, which could be used in treatment of pediatric CD. The purpose of our review is to point out the impact of dietary therapy on achieving remission in pediatric Crohn’s disease.

Materials and methods: We have reviewed the literature from the PubMed database searching for clinical trials, meta analysis and randomized controlled trials from the past years. The keywords we agreed on offered us the most informative articles and made us hope for the further development of our article.

Brief Description Of The State Of Knowledge: Steroid therapy is the principle of CD treatment, but it has a number of side effects that influence the quality of pediatric patients’ life. It has been shown that the use of dietary therapies (EEN, CDED+PEN, SCD) enables the achievement of clinical and biochemical remission, mucosal healing and regulation of dysbiosis. There are many hypotheses explaining this effect, probably the reason of this is the exclusion from the diet of food products that provoke inflammatory processes.

Summary: Despite its effectiveness, dietary therapies require motivation and full commitment from patients in order to achieve results. That is why it is so important to conduct further research in this area so that the selected therapy is as acceptable and tolerated by the patient as possible. In addition, education of children and parents, psychological and dietary support are also crucial in the treatment process.

References

Scarallo L, Banci E, Pierattini V, Lionetti P. Crohn’s disease exclusion diet in children with Crohn’s disease: a case series, Current Medical Research and Opinion, 2021 Jul;37:7, 1115-1120, DOI: 10.1080/03007995.2021.1920901 PMID: 33951997

Thorne K, Thapar N, Broekaert I, Benninga M A, Dolinsek J, Mas E, et al. A systematic review and meta analysis of paediatric inflammatory bowel disease incidence and prevalence across Europe, 2020 Sep 7;14(8):1119-1148. doi: 10.1093/ecco-jcc/jjaa037. PMID: 32115645

Narula N, Dhillon A, Zhang D, Sherlock M, Tondeur M, Zachos M. Enteral nutritional therapy for induction of remission in Crohn's disease Cochrane Database Sys Rev. 2018 Apr 1;4(4):CD000542. doi: 10.1002/14651858.CD000542.pub3. PMID: 29607496 PMCID: PMC6494406

Svolos V, Hansen R, Nichols B, Quince Ch, Ijaz U Z, Papadopoulou R T, et al.Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition, 2019 Apr;156(5):1354-1367.e6. doi: 10.1053/j.gastro.2018.12.002. Epub 2018 Dec 11. PMID: 30550821

Horowitz J E, Warner N, Staples J, Crowley E, Gosalia N, Murchie R, et al. Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn's Disease, Scientific Reports 2021 Mar 10;11(1):5595. doi: 10.1038/s41598-021-84938-8, PMID: 33692434 PMCID: PMC7946957

Ghiboub M, Boneh R, Sovran B, Wine E, Lefèvre A, Emond P, et al. Sustained Diet-Induced Remission in Pediatric Crohn's Disease Is Associated With Kynurenine and Serotonin Pathways, 2023 Jan 13;izac262.doi: 10.1093/ibd/izac262. PMID: 36637175

Suskind D L, Lee D, Kim Y M, Wahbeh G, Singh N, Braly K, et al. The Specific Carbohydrate Diet and Diet Modification as Induction Therapy for Pediatric Crohn's Disease: A Randomized Diet Controlled Trial, 2020 Dec 6;12(12):3749. doi: 10.3390/nu12123749 PMID: 33291229 PMCID: PMC7762109

Levine A, Wine E, Assa A, Boneh R S, Shaoul R, Kori M, et al. Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial. Gastroenterology. 2019 Aug;157(2):440-450.e8. doi: 10.1053/j.gastro.2019.04.021. Epub 2019 Jun 4. PMID: 31170412

Moriczi M, Pujol-Muncunill G, Martín-Masot R, Jiménez Treviño S , Segarra Cantón O , Ochoa Sangrador C, Peña Quintana L, et al. Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP, 2020 Apr 7;12(4):1012. doi: 10.3390/nu12041012. PMID: 32272604 PMCID: PMC723125

Suskind D, Wahbeh G, Gregory N, Vendettuoli H, Christie D. Nutritional therapy in pediatric Crohn disease: the specific carbohydrate diet, 2014 Jan;58(1):87-91. doi: 10.1097/MPG.0000000000000103. PMID: 24048168

Wehkamp J, Götz M, Herrlinger K, Steurer W, Stange E F. Inflammatory Bowel Disease, Dtsch Arztebl Int. 2016 Feb 5;113(5):72-82. doi: 10.3238/arztebl.2016.0072. PMID: 26900160 PMC4782273

Roda G, Chien Ng S, Kotze P G, Argollo M, Panaccione R, Spinelli A, et al. Crohn's disease, 2020 Apr 2;6(1):22. doi: 10.1038/s41572-020-0156-2, PMID: 32242028

Danese S, Sandborn W J, Colombel J F, Vermeire S, Glover S C, Rimola J, et al. Endoscopic, Radiologic, and Histologic Healing With Vedolizumab in Patients With Active Crohn's Disease, 2019 Oct;157(4):1007-1018.e7. doi: 10.1053/j.gastro.2019.06.038. Epub 2019 Jul 4, PMID: 31279871

Mosli M H, Zou G, Garg S K, Feagan S G, MacDonald J K, Chande N, Sandborn W J, Feagan B G. C-Reactive Protein, Fecal Calprotectin, and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis, 2015 Jun;110(6):802-19; quiz 820. doi: 10.1038/ajg.2015.120. Epub 2015 May 12, PMID: 25964225

Hyun Jin K, Young K, Jin Min Ch, Seak Hee O, Kyung Mo K. Therapeutic Efficacy of Oral Enteral Nutrition in Pediatric Crohn's Disease: A Single Center Non-Comparative Retrospective Study. Yonsei Med J. 2016 Sep;57(5):1185-91. doi:10.3349/ymj.2016.57.5.1185. PMID: 27401650 PMCID: PMC4960385.

Dziechciarz P, Horvath A, Shamir R, Szajewska H. Meta-analysis: enteral nutrition in active Crohn's disease in children. Aliment Pharmacol Ther. 2007 Sep 15;26(6):795-806. doi: 10.1111/j.1365-2036.2007.03431.x.

Pigneur B, Lepage P, Mondot S, Schmitz J, Goulet O, Doré J, Ruemmele F M. Mucosal Healing and Bacterial Composition in Response to Enteral Nutrition Vs Steroid-based Induction Therapy-A Randomised Prospective Clinical Trial in Children With Crohn's Disease. J Crohns Colitis. 2019 Jul 25;13(7):846-855. doi: 10.1093/ecco-jcc/jjy207. PMID: 30541015

Ghiboub M, Penny S, Verburgt Ch M, Boneh R S, Wine E, Cohen A, et al. Metabolome Changes With Diet-Induced Remission in Pediatric Crohn's Disease. Gastroenterology. 2022 Oct;163(4):922-936.e15. doi: 10.1053/j.gastro.2022.05.050. Epub 2022 Jun 7.

PMID: 35679949

Urlep D, Benedik E, Brecelj J, Orel R. Partial enteral nutrition induces clinical and endoscopic remission in active pediatric Crohn's disease: results of a prospective cohort study. Eur J Pediatr.2020 Mar;179(3):431-438. doi: 10.1007/s00431-019-03520-7. Epub 2019 Nov 28. PMID: 31781933

Lee D, Baldassano R N, Otley R A, Albenberg L, Griffiths A M, Compher Ch, et al. Comparative Effectiveness of Nutritional and Biological Therapy in North American Children with Active Crohn's Disease. Inflamm Bowel Disease, 2015 Aug;21(8):1786-93. doi: 10.1097/MIB.0000000000000426 PMID: 25970545

Blaak E E, Canfora E E, Theis S, Frost G, Groen A K, Mithieux G, et al. Short chain fatty acids in human gut and metabolic health. Benef Microbes. 2020 Sep 1;11(5):411-455. doi: 10.3920/BM2020.0057. Epub 2020 Aug 31. PMID: 32865024

Boneh R S, Van Limbergen J, Wine E, Assa A, Shaoul R, Milman P, et al. Dietary Therapies Induce Rapid Response and Remission in Pediatric Patients With Active Crohn's Disease. Clin Gastroenterol Hepatol. 2021 Apr;19(4):752-759. doi: 10.1016/j.cgh.2020.04.006. Epub 2020 Apr 14. PMID: 32302709

https://j-elita.org.pl/aktualnosci/modulife-to-nie-tylko-dieta-to-takze-przepis-na-zycie-w-chorobie-crohna/

Braly K, Williamson N, Shaffer M L, Lee D, Wahbeh G, Klein J, Giefer M, Suskind D L. Nutritional Adequacy of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease, 2017 Nov;65(5):533-538. doi: 10.1097/MPG.0000000000001613 PMID: 28825603 PMCID: PMC5653423

Cohen S A, Gold B G, Oliva S, Lewis J, Stallworth A, Koch B, Eshee L, Mason D. Clinical and mucosal improvement with specific carbohydrate diet in pediatric Crohn disease, 2014 Oct;59(4):516-21. doi: 10.1097/MPG.0000000000000449 PMID: 24897165

Sigall-Boneh R, Pfeffer-Gik T, Segal I, Zangen T, Boaz M, Levine A. Partial enteral nutrition with a Crohn's disease exclusion diet is effective for induction of remission in children and young adults with Crohn's disease. Inflamm Bowel Dis. 2014 Aug;20(8):1353-60. doi: 10.1097/MIB.0000000000000110. PMID: 24983973

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Published

2023-04-19

How to Cite

1.
KAMIŃSKA, Izabela, PAWŁOCIK, Weronika, PAWLAK, Weronika, GRABOWSKA, Ewa, SZYMAŃSKA, Julia, WOJTALA, Laura, RYMARZ, Anna, KOJDER, Dominika, PIEKARSKA, Małgorzata and JEDLINA, Klaudia. Dietary Therapies in Pediatric Crohn’s Disease. Journal of Education, Health and Sport. Online. 19 April 2023. Vol. 21, no. 1, pp. 47-53. [Accessed 29 June 2025]. DOI 10.12775/JEHS.2023.21.01.005.
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Copyright (c) 2023 Izabela Kamińska, Weronika Pawłocik, Weronika Pawlak, Ewa Grabowska, Julia Szymańska, Laura Wojtala, Anna Rymarz, Dominika Kojder, Małgorzata Piekarska, Klaudia Jedlina

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