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Journal of Education, Health and Sport

The immunomodulatory phenomenon of vitamin D in the pathogenesis of Multiple Sclerosis
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  • The immunomodulatory phenomenon of vitamin D in the pathogenesis of Multiple Sclerosis
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The immunomodulatory phenomenon of vitamin D in the pathogenesis of Multiple Sclerosis

Authors

  • Karolina Raksa Student, Wydział Lekarski, Uniwersytet Medyczny w Lublinie Studenckie Koło Naukowe przy Katedrze i Zakładzie Epidemiologii i Metodologii Badań Klinicznych https://orcid.org/0000-0001-5571-1035
  • Mateusz Pawlina Student, Wydział Lekarski, Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0001-7354-4883
  • Karolina Ziętara Student, Wydział Lekarski, Uniwersytet Medyczny w Lublinie, Studenckie Koło Naukowe przy Katedrze Psychologii https://orcid.org/0000-0002-6754-9263
  • Aleksander Oskroba Student, Wydział Lekarski, Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0003-0783-4895
  • Aleksandra Orzechowska Studentka, Wydział Lekarski, Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0002-6919-0928
  • Natalia Pawełczak Studentka, Wydział Lekarski, Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0001-9933-258X
  • Bartłomiej Zielonka 1 Wojskowy Szpital Kliniczny w Lublinie https://orcid.org/0000-0001-7788-1342
  • Ilona Kowalczyk Samodzielny Publiczny Szpital Kliniczny im. prof. W. Orłowskiego CMKP w Warszawie https://orcid.org/0000-0002-8669-3068
  • Piotr Pawłowski Student, Wydział Lekarski, Uniwersytet Medyczny w Lublinie, Studenckie Koło Naukowe przy Katedrze Rozwoju Pielęgniarstwa https://orcid.org/0000-0002-1197-7218
  • Cezary Stawikowski 1 Wojskowy Szpital Kliniczny w Lublinie https://orcid.org/0000-0003-3026-8617

DOI:

https://doi.org/10.12775/JEHS.2023.14.01.004

Keywords

vitamin D, multiple sclerosis, nervous system

Abstract

People living in areas with limited access to sunlight, do not produce enough vitamin D and are more likely to suffer from Multiple Sclerosis.Near the equator, where there is high exposure to the sun, the disease is almost non-existent.

Aim of the study: The study aimto statistical data on the literature and presents the current state of Vitamin D deficiency as a risk factor in multiple sclerosis.

Material and method: The method of study is descriptive epidemiological analysis. Information that has been used is derived from statistical data provided by the WHO. In searching for them on the WHO, PubMed website, Google Scholar, and SCOPUS.

Results and conclusions: Vitamin D is a regulator of calcium and phosphorus levels and affects the development and proper functioning of the nervous system. Patients with Multiple sclerosis often have low serum vitamin D levels, which tend to decrease as the disease progresses. There are theories that a deficiency of this vitamin promotes autoimmune, inflammatory demyelination.

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2023-03-14

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RAKSA, Karolina, PAWLINA, Mateusz, ZIĘTARA, Karolina, OSKROBA, Aleksander, ORZECHOWSKA, Aleksandra, PAWEŁCZAK, Natalia, ZIELONKA, Bartłomiej, KOWALCZYK, Ilona, PAWŁOWSKI, Piotr and STAWIKOWSKI, Cezary. The immunomodulatory phenomenon of vitamin D in the pathogenesis of Multiple Sclerosis. Journal of Education, Health and Sport. Online. 14 March 2023. Vol. 14, no. 1, pp. 32-42. [Accessed 4 July 2025]. DOI 10.12775/JEHS.2023.14.01.004.
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Copyright (c) 2023 Karolina Raksa, Mateusz Pawlina, Karolina Ziętara, Aleksander Oskroba, Aleksandra Orzechowska, Natalia Pawełczak, Bartłomiej Zielonka, Ilona Kowalczyk, Piotr Pawłowski, Cezary Stawikowski

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