The effectiveness of negative pressure wound therapy compared to the traditional method in the treatment of diabetic foot
DOI:
https://doi.org/10.12775/JEHS.2023.16.01.003Keywords
negative pressure wound therapy, VAC therapy, traditional dressing, standard moist wound care, diabetic footAbstract
Introduction and objective: Diabetes is one of the most common metabolic diseases in the world. Diabetic foot ulcers, which are often the result of the disease, are undoubtedly a nursing challenge. Negative pressure wound therapy (NPWT) is a new therapeutic method supporting wound healing, which has been useful in patients with diabetic foot. The purpose of this study is to compare the effectiveness of negative pressure therapy in comparison to the standard method in the treatment of diabetic foot.
Review methods: In February 2023, articles found in the Medline (Pubmed) and Google Scholar databases were selected by using the following keywords: negative pressure wound therapy; VAC therapy; traditional dressing; standard moist wound care; diabetic foot.
Brief description of the state of knowledge: NPWT has been proven to be associated with reduced healing time and faster appearance of granulation tissue, which is a sign of wound healing. Patients using this method require fewer dressing changes and surgical cleanings. Negative pressure therapy reduces the time to rehospitalisation and the risk of amputation or resection of the diabetic foot.
Summary: Negative pressure wound therapy is more effective in the treatment of diabetic foot ulcers than traditional therapy. Despite the costs associated with NPWT being higher, the method proves to be more profitable. It is important to remember about good therapy technique and proper selection of patients.
References
F. Qi, H. Huang, Y. Cai, and Z. Fu, “Adjacent Fu’s subcutaneous needling as an adjunctive healing strategy for diabetic foot ulcers: Two case reports,” Medicine, vol. 101, no. 50, p. e32271, Dec. 2022, doi: 10.1097/MD.0000000000032271.
A. S. Rayate, B. S. Nagoba, S. S. Mumbre, H. B. Mavani, A. M. Gavkare, and A. S. Deshpande, “Current scenario of traditional medicines in management of diabetic foot ulcers: A review,” World J Diabetes, vol. 14, no. 1, p. 1, Jan. 2023, doi: 10.4239/WJD.V14.I1.1.
F. Niami et al., “Evaluation of the effect of a gel made with amniotic fluid formulation on the healing of diabetic foot ulcers: A triple-blind clinical trial,” Front Public Health, vol. 10, Dec. 2022, doi: 10.3389/FPUBH.2022.1025391.
Y. Wang et al., “Risk factors for diabetic foot ulcers mortality and novel negative pressure combined with platelet-rich plasma therapy in the treatment of diabetic foot ulcers,” Front Pharmacol, vol. 13, Dec. 2022, doi: 10.3389/FPHAR.2022.1051299.
G. J. Vazquez-Zapien et al., “Skin wound healing improvement in diabetic mice through FTIR microspectroscopy after implanting pluripotent stem cells,” APL Bioeng, vol. 7, no. 1, p. 16109, Mar. 2023, doi: 10.1063/5.0130383.
K. Hajimohammadi, K. Makhdoomi, R. E. Zabihi, and N. Parizad, “NPWT: a gate of hope for patients with diabetic foot ulcers,” Br J Nurs, vol. 28, no. 12, pp. S6–S9, Jun. 2019, doi: 10.12968/BJON.2019.28.12.S6.
V. Zaver and P. Kankanalu, “Negative Pressure Wound Therapy,” StatPearls, Sep. 2022, Accessed: Jan. 09, 2023. [Online]. Available: https://www.ncbi.nlm.nih.gov/books/NBK576388/
D.-Z. Lin, Y.-C. Kao, C. Chen, H.-J. Wang, and W.-K. Chiu, “Negative pressure wound therapy for burn patients: A meta-analysis and systematic review.,” Int Wound J, vol. 18, no. 1, pp. 112–123, Feb. 2021, doi: 10.1111/iwj.13500.
M. O. Sergeenko Pavlova, Y. M. Korostelev, G. N. Shikhaleva, M. D. Savin, Y. E. Filatov, and O. S. Ryabykh, “Negative pressure wound therapy in cases of spinal surgery and exposed dura: a case-based review.,” Childs Nerv Syst, vol. 37, no. 10, pp. 2975–2981, Oct. 2021, doi: 10.1007/s00381-021-05302-9.
F. M. Carrano et al., “Negative-pressure wound therapy after stoma reversal in colorectal surgery: a randomized controlled trial.,” BJS Open, vol. 5, no. 6, Nov. 2021, doi: 10.1093/bjsopen/zrab116.
Y. Cheng et al., “Negative pressure wound therapy for managing the open abdomen in non-trauma patients.,” Cochrane Database Syst Rev, vol. 5, no. 5, p. CD013710, May 2022, doi: 10.1002/14651858.CD013710.pub2.
J. S. Mervis and T. J. Phillips, “Pressure ulcers: Prevention and management.,” J Am Acad Dermatol, vol. 81, no. 4, pp. 893–902, Oct. 2019, doi: 10.1016/j.jaad.2018.12.068.
N. L. Van Rysselberghe, C. A. Gonzalez, C. Calderon, A. Mansour, Y. A. Oquendo, and M. J. Gardner, “Negative Pressure Wound Therapy for Extremity Open Wound Management: A Review of the Literature,” J Orthop Trauma, vol. 36, no. 4, pp. S6–S11, Sep. 2022, doi: 10.1097/BOT.0000000000002430.
R. Grande, G. Fiori, G. Russo, P. Fioramonti, M. Campagnol, and L. di Marzo, “A multistage combined approach to promote diabetic wound healing in COVID-19 era.,” Int Wound J, vol. 17, no. 6, pp. 1863–1870, Dec. 2020, doi: 10.1111/iwj.13476.
S. Borys, J. Hohendorff, C. Frankfurter, B. Kiec-Wilk, and M. T. Malecki, “Negative pressure wound therapy use in diabetic foot syndrome-from mechanisms of action to clinical practice.,” Eur J Clin Invest, vol. 49, no. 4, p. e13067, Apr. 2019, doi: 10.1111/eci.13067.
L. Liu et al., “Downregulation of hsa-miR-203 in peripheral blood and wound margin tissue by negative pressure wound therapy contributes to wound healing of diabetic foot ulcers.,” Microvasc Res, vol. 139, p. 104275, Jan. 2022, doi: 10.1016/j.mvr.2021.104275.
N. A. Richmond, A. C. Vivas, and R. S. Kirsner, “Topical and biologic therapies for diabetic foot ulcers,” Med Clin North Am, vol. 97, no. 5, pp. 883–898, Sep. 2013, doi: 10.1016/J.MCNA.2013.03.014.
R. Eldor, I. Raz, A. ben Yehuda, and A. J. M. Boulton, “New and experimental approaches to treatment of diabetic foot ulcers: a comprehensive review of emerging treatment strategies,” Diabetic Medicine, vol. 21, no. 11, pp. 1161–1173, Nov. 2004, doi: 10.1111/J.1464-5491.2004.01358.X.
T. R. Bellomo et al., “Management of the diabetic foot,” Semin Vasc Surg, vol. 35, no. 2, pp. 219–227, Jun. 2022, doi: 10.1053/J.SEMVASCSURG.2022.04.002.
D. Seidel et al., “NPWT resource use compared with standard moist wound care in diabetic foot wounds: DiaFu randomized clinical trial results,” J Foot Ankle Res, vol. 15, no. 1, p. 72, Dec. 2022, doi: 10.1186/S13047-022-00569-W.
S. M. D. James, S. Sureshkumar, T. P. Elamurugan, N. Debasis, C. Vijayakumar, and C. Palanivel, “Comparison of Vacuum-Assisted Closure Therapy and Conventional Dressing on Wound Healing in Patients with Diabetic Foot Ulcer: A Randomized Controlled Trial,” Niger J Surg, vol. 25, no. 1, p. 14, 2019, doi: 10.4103/NJS.NJS_14_18.
E. Sukur et al., “Vacuum-assisted closure versus moist dressings in the treatment of diabetic wound ulcers after partial foot amputation: A retrospective analysis in 65 patients,” Journal of Orthopaedic Surgery, vol. 26, no. 3, Sep. 2018, doi: 10.1177/2309499018799769/ASSET/IMAGES/LARGE/10.1177_2309499018799769-FIG2.JPEG.
N. Wang, S. S. Li, Y. P. Liu, Y. Y. Peng, and P. F. Wang, “Comparison of negative pressure wound therapy and moist wound care in patients with diabetic foot ulcers: A protocol for systematic review and meta-analysis of randomized controlled trials,” Medicine, vol. 101, no. 31, p. E29537, Aug. 2022, doi: 10.1097/MD.0000000000029537.
Q. Huang, J. T. Wang, H. C. Gu, G. Cao, and J. C. Cao, “Comparison of Vacuum Sealing Drainage and Traditional Therapy for Treatment of Diabetic Foot Ulcers: A Meta-Analysis,” The Journal of Foot and Ankle Surgery, vol. 58, no. 5, pp. 954–958, Sep. 2019, doi: 10.1053/J.JFAS.2018.12.020.
V. Alipour, A. Rezapour, M. Ebrahimi, and J. Arabloo, “Cost-Utility Analysis of Negative Pressure Wound Therapy Compared With Traditional Wound Care in the Treatment of Diabetic Foot Ulcers in Iran.,” Wounds, vol. 33, no. 2, pp. 50–56, Feb. 2021, Accessed: Feb. 18, 2023. [Online]. Available: https://europepmc.org/article/med/33591928
S. Flack, J. Apelqvist, M. Keith, P. Trueman, and D. Williams, “An economic evaluation of VAC therapy compared with wound dressings in the treatment of diabetic foot ulcers,” J Wound Care, vol. 17, no. 2, pp. 71–78, 2008, doi: 10.12968/JOWC.2008.17.2.28181.
V. Zaver and P. Kankanalu, “Negative Pressure Wound Therapy,” StatPearls, Sep. 2022, Accessed: Feb. 18, 2023. [Online]. Available: https://www.ncbi.nlm.nih.gov/books/NBK576388/
S. Normandin et al., “Healing, Inflammation, and Fibrosis: Negative Pressure Wound Therapy: Mechanism of Action and Clinical Applications,” Semin Plast Surg, vol. 35, no. 3, p. 164, Aug. 2021, doi: 10.1055/S-0041-1731792.
M. A. Secretariat, “Negative Pressure Wound Therapy: An Evidence-Based Analysis,” Ont Health Technol Assess Ser, vol. 6, no. 14, p. 1, 2006, Accessed: Feb. 18, 2023. [Online]. Available: /pmc/articles/PMC3379164/
G. Norman et al., “Negative pressure wound therapy for surgical wounds healing by primary closure,” Cochrane Database Syst Rev, vol. 2022, no. 4, Apr. 2022, doi: 10.1002/14651858.CD009261.PUB7.
R. Kahveci and T. W. W. Group, “Negative Pressure Wound Therapy for Complex Surgical Wounds in 59 Patients Across Secondary and Tertiary Care Centers in Turkey,” Eplasty, vol. 22, 2022, Accessed: Feb. 18, 2023. [Online]. Available: /pmc/articles/PMC9748823/
D. V. Abeysuriya, U. Thilakawardana, D. Abeysuriya, L. Chandrasena, D. Mohan, and S. Seneviratne, “Effect on length of stay (LOS) and cost of hospitalization by using Vacuum-assisted Closure (VAC) therapy in chronic diabetic foot ulcers: Experience with limited resources in a developing country,” 2020.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Julia Bogucka, Anna Brzyska, Małgorzata Bojarska, Bartosz Burda
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 1324
Number of citations: 0