The role of clinical-anamnestic indices in diagnostics of severe persisting bronchial asthma in children

Abstract

Khilchevska V. S., Kolyubakina L. V. The role of clinical-anamnestic indices in diagnostics of severe persisting bronchial asthma in children. Journal of Education, Health and Sport. 2017;7(1):293-299. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.260199

http://ojs.ukw.edu.pl/index.php/johs/article/view/4199

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© The Author (s) 2017;

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This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017.

THE ROLE OF CLINICAL-ANAMNESTIC INDICES IN DIAGNOSTICS OF SEVERE PERSISTING BRONCHIAL ASTHMA IN CHILDREN

V. S. Khilchevska, L. V. Kolyubakina

Higher State Educational Establishment of Ukraine

«Bukovinian State Medical University», Chernivtsi, Ukraine

Abstract

Performed integral estimation of the diagnostic value of the obtained clinical-paraclinical parameters is indicative of a sufficient amount of reliable markers in verification of severe bronchial asthma (BA) in children. Children with severe bronchial asthma are characterized by the following phenotype peculiarities: early debut of the disease (chance ratio (CR) = 1,5 (95% confidence interval (CI) 0,9-2,7), comorbid allergic diseases available (allergic rhinitis and atopic dermatitis) (CR 2,7 (95% CI 1,5-4,8) and drug-induced or comorbid drug-induced and food or domestic allergy (CR=4,8 (95% CІ 0,1-36,5)), infectious index more than 2 (CR=3,3 (95% CІ 1,6-6,7), seasonal exacerbation of BA mainly from November to March (СR=2,7 (95% CІ 1,5-4,9), associated with a trigger role of acute respiratory viral infection (ARVI) (СR=5,5 (95% CІ 2,4-12,6) and meteorological factors (СR=3,8 (95% CІ 0,4-36,4).

Key words: children, bronchial asthma, clinical-anamnestic indices, sensitivity, specificity.