The role of vitamin D in the human body and the benefits and risks of its supplementation
DOI:
https://doi.org/10.12775/JEHS.2022.12.12.051Keywords
vitamin D, vitamin D deficiency, supplementation, toxicityAbstract
The prevalence of vitamin D deficiency in society and the growing awareness of related health problems have resulted in the widespread use of vitamin D supplementation. The source of vitamin D is skin synthesis with the participation of ultraviolet radiation (UVB) and its supply with the diet. The inability to cover the daily requirement for vitamin D without an additional source of vitamin D means that the society most often reaches for dietary supplements that do not have the properties of a medicinal product. The use of over-the-counter supplements, where the actual dose of the vitamin may differ from the dose declared by the manufacturers, may result in a lack of benefit from the food product when the vitamin D content is too low or lead to hypervitaminosis when the content is too high.
References
Mikrobiologia Patrick R. Murray, Michael A. Pfaller, Ken S. Rosenthal Wydanie 8 Wydawca: Edra Urban & Partner
Bates, B, Lennox, A, Prentice, A et al. (2014) National Diet and Nutrition Survey Rolling Programme (NDNS RP). Results from years 1–4 (combined) for Scotland (2008/9–2011/12). Public Health England and Food Standards Agency in Scotland.Google Scholar
Korzyści i zagrożenia wynikające z suplementacji witaminą D Piotr Kmieć Krzysztof Sworczak Forum Medycyny Rodzinnej 2017;11(1):38-46.
Galior, K.; Grebe, S.; Singh, R. Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports. Nutrients 2018, 10, 953. https://doi.org/10.3390/nu100809535
E. Bańkowski „Biochemia”, wyd.4 2020, wyd. Edra Urban & Partner
Sawicki, Krzysztof B., and Waldemar Skawiński. "Witamina D3 – fundamentalny komponent zdrowia człowieka oraz potencjalny suplement w zapobieganiu i terapii COVID-19". Med Og Nauk Zdr. 27 no. 3 (2021): 227-234. doi:10.26444/monz/140406.
Rola witaminy D w praktyce ortopedycznej. (The significance of vitamin D in orthopaedics.). Paweł Łęgosz, Sylwia Sarzyńska, Robert Dubel, Paweł Małdyk.Praktyczna Ortopedia i Traumatologia 2021 nr 22, s. 43-51, bibliogr. poz. 33, sum.
Maj, Dominik, Et Al. "Związek Pomiędzy Poziomem Witaminy D A Przebiegiem Klinicznym Covid-19." Zdrowie Człowieka–: 9.
Delvin, E.; Souberbielle, J.C.; Viard, J.P.; Salle, B. Role of vitamin D in acquired immune and autoimmune diseases. Crit. Rev. Clin. Lab. Sci. 2014, 51, 232–247.
Brewer, L.C.; Michos, E.D.; Reis, J.P. Vitamin D in atherosclerosis, vascular disease, and endothelial function. Curr. Drug Targets 2011, 12, 54–60.
Rizzoli, R. Nutritional aspects of bone health. Best Pract. Res. Clin. Endocrinol. Metab. 2014, 28, 795–808
Ciborowska H, Rudnicka A.: „Dietetyka. Żywienie zdrowego i chorego człowieka”. Warszawa, PZWL 2009
Ann R. Webb, Who, what, where and when-influences on cutaneous vitamin D synthesis, „Progress in Biophysics and Molecular Biology”, 92 (1), 2006, s. 17–25, DOI: 10.1016/j.pbiomolbio.2006.02.004, PMID: 16766240.
Wytyczne dla lekarzy rodzinnych dotyczące suplementacji witaminy D -Recommendations for vitamin D supplementation Zalecenia opracowane przez Polską Grupę Roboczą International University Family
Medicine Club
Wilson LR, Tripkovic L, Hart KH, Lanham-New SA. Vitamin D deficiency as a public health issue: using vitamin D2 or vitamin D3 in future fortification strategies. Proc Nutr Soc. 2017 Aug;76(3):392-399. doi: 10.1017/S0029665117000349. Epub 2017 Mar 28. PMID: 28347378
Galior, K.; Grebe, S.; Singh, R. Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports. Nutrients 2018, 10, 953. https://doi.org/10.3390/nu10080953
Tian-Tian Wang i inni, Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression, „Journal of Immunology (Baltimore, Md.: 1950)”, 173 (5), 2004, s. 2909–2912, DOI: 10.4049/jimmunol.173.5.2909, PMID: 15322146.
Stefanie S Schleithoff i inni, Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial, „The American Journal of Clinical Nutrition”, 83 (4), 2006, s. 754–759, DOI: 10.1093/ajcn/83.4.754 [dostęp 2018-06-17] (ang.).
David E. McCarty i inni, The link between vitamin D metabolism and sleep medicine, „Sleep Medicine Reviews”, 18 (4), 2014, s. 311–319, DOI: 10.1016/j.smrv.2013.07.001, PMID: 24075129.
David E. McCarty i inni, Vitamin D, race, and excessive daytime sleepiness, „Journal of clinical sleep medicine: JCSM”, 8 (6), 2012, s. 693–697, DOI: 10.5664/jcsm.2266, PMID: 23243403, PMCID: PMC3501666.
F.M. Gloth i inni, Can vitamin D deficiency produce an unusual pain syndrome?, „Archives of Internal Medicine”, 151 (8), 1991, s. 1662–1664, PMID: 1872673
Gregory A. Plotnikoff, Joanna M. Quigley, Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain, „Mayo Clinic Proceedings”, 78 (12), 2003, s. 1463–1470, DOI: 10.4065/78.12.1463, PMID: 14661675.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Julia Dubel, Natalia Namroży, Robert Dubel, Aleksandra Czekaj, Kinga Ruszel, Sylwia Zdun, Agnieszka Marciniak, Natalia Grzywna, Patrycja Walczak, Klaudia Walczak
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 665
Number of citations: 0
