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Journal of Education, Health and Sport

Urinary tract infection in children - short versus standard duration antibiotic therapy
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Urinary tract infection in children - short versus standard duration antibiotic therapy

Authors

  • Natalia Namroży Clinical Hospital No.4, Jaczewskiego Street 8, 20-954 Lublin, Poland https://orcid.org/0000-0002-7553-4395
  • Robert Dubel Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0001-7666-2893
  • Aleksandra Czekaj Wojewódzki Szpital Specjalistyczny Nr 1 imienia Fryderyka Chopina w Rzeszowie https://orcid.org/0000-0003-3104-683X
  • Kinga Ruszel Wojskowy Szpital Kliniczny Nr 1 w Lublinie https://orcid.org/0000-0002-9633-4288
  • Julia Dubel Warszawski Uniwersytet Medyczny https://orcid.org/0000-0002-4854-2912
  • Konrad Merkisz Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0002-3533-2967
  • Sylwia Nemeczek Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0003-2936-1822
  • Jakub Grzybowski Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0002-2110-7304
  • Karolina Jaskuła Wojewódzki Szpital Specjalistyczny Nr 1 imienia Fryderyka Chopina w Rzeszowie https://orcid.org/0000-0002-0040-4545
  • Władysław Orłowski Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego SPZOZ w Lublinie https://orcid.org/0000-0002-8191-2102

DOI:

https://doi.org/10.12775/JEHS.2023.13.02.013

Keywords

urinarytractinfection, pediatrics, pediatricnephrology

Abstract

Background: Urinary Tract Infection (UTI) is a common infection in children. Prompt diagnosis and appropriate treatment are very important to reduce the morbidity. Pediatric urologists are now faced with a situation that requires appropriate action- antibiotic resistance of urinary tract pathogens is significantly increasing worldwide.

Objective: The purpose of our work is to present the clinical aspects of antibiotic use in pediatric urology. To present the benefits of both short antibiotic therapy and standard antibiotic therapy. 

Methods and materials: A literature review was conducted in the PubMed database, using the key words: "urinary tract infection", "children", "short-term antibiotics", "antibiotics", „nephrology”.

Results: Short-term antibiotic therapy for lower urinary tract infections appears to be as effective as standard therapy. Studies show that shorter antibiotic therapy also works well for pyelonephritis in pediatric patients. Children who have received a short course of antibiotic therapy may also be less likely to get subsequent infections in the future with a more resistant strain of the same uropathogen.

Conclusion: Tried to reconcile the latest reports on diagnosis, treatment and follow-up in pediatric UTIs with existing practice and opinions on the use of short as well as standard antibiotic therapy. However, more clinical trials are needed to confirm efficacy, and to assess side effects of the therapy 

References

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Leung AKC, Wong AHC, Leung AAM, Hon KL. Urinary Tract Infection in Children. Recent Pat Inflamm Allergy Drug Discov. 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257; PMCID: PMC6751349.

Gondim R., Azevedo R., Braga A.A.N.M., Veiga M.L., Barroso U., Jr Risk factors for urinary tract infection in children with urinary urgency. Int. Braz J Urol. 2018;44(2):378–383

Okarska-Napierała M, Wasilewska A, Kuchar E. Urinary tract infection in children: Diagnosis, treatment, imaging – Comparison of current guidelines. J Pediatr Urol. 2017;13(6):567-573. doi:10.1016/j.jpurol.2017.07.018 9. Excellence NI for H and C, NICE. Urinary tract infection in under 16s : diagnosis and management. Nice. 2018;(August 2007):1-27. 10. White B. Diagnosis and treatment of urinary tract infections in children. Am Fam Physician. 2011 Feb 15;83(4):409-15. PMID: 21322515. 11. Finnell SM, Carroll AE, Downs SM; Subcommittee on Urinary Tract Infection. Technical report—Diagnosis and management of an initial UTI in febrile infants and young children. Pediatrics. 2011 Sep;128(3):e749-70. doi: 10.1542/peds.2011-1332. Epub 2011 Aug 28. PMID: 21873694.

Williams G, Craig JC. Long-term antibiotics for preventing recurrent urinary tract infection in children. Cochrane Database Syst Rev. 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167; PMCID: PMC6442022. 13. Buonsenso D, Sodero G, Mariani F, Lazzareschi I, Proli F, Zampino G, Pierantoni L, Valentini P, Rendeli C. Comparison between Short Therapy and Standard Therapy in Pediatric Patients Hospitalized with Urinary Tract Infection: A Single Center Retrospective Analysis. Children (Basel). 2022 Oct 28;9(11):1647. doi: 10.3390/children9111647. PMID: 36360375; PMCID: PMC9688884.

Kutasy B, Coyle D, Fossum M. Urinary Tract Infection in Children: Management in the Era of Antibiotic Resistance-A Pediatric Urologist's View. Eur Urol Focus. 2017 Apr;3(2-3):207-211. doi: 10.1016/j.euf.2017.09.013. Epub 2017 Sep 29. PMID: 28965960.

Vazouras K, Velali K, Tassiou I, Anastasiou-Katsiardani A, Athanasopoulou K, Barbouni A, Jackson C, Folgori L, Zaoutis T, Basmaci R, Hsia Y. Antibiotic treatment and antimicrobial resistance in children with urinary tract infections. J Glob Antimicrob Resist. 2020 Mar;20:4-10. doi: 10.1016/j.jgar.2019.06.016. Epub 2019 Jun 25. PMID: 31252156.

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Fox MT, Amoah J, Hsu AJ, Herzke CA, Gerber JS, Tamma PD. Comparative Effectiveness of Antibiotic Treatment Duration in Children With Pyelonephritis. JAMA Netw Open. 2020 May 1;3(5):e203951. doi: 10.1001/jamanetworkopen.2020.3951. PMID: 32364593; PMCID: PMC7199115.

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Published

2022-12-20

How to Cite

1.
NAMROŻY, Natalia, DUBEL, Robert, CZEKAJ, Aleksandra, RUSZEL, Kinga, DUBEL, Julia, MERKISZ, Konrad, NEMECZEK, Sylwia, GRZYBOWSKI, Jakub, JASKUŁA, Karolina and ORŁOWSKI, Władysław. Urinary tract infection in children - short versus standard duration antibiotic therapy. Journal of Education, Health and Sport. Online. 20 December 2022. Vol. 13, no. 2, pp. 98-103. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2023.13.02.013.
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Vol. 13 No. 2 (2023)

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Short Articles

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Copyright (c) 2022 Natalia Namroży, Robert Dubel, Aleksandra Czekaj, Kinga Ruszel, Julia Dubel, Konrad Merkisz, Sylwia Nemeczek, Jakub Grzybowski, Karolina Jaskuła, Władysław Orłowski

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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