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Journal of Education, Health and Sport

A brand new medical condition - 6 years old patient with neurological symptoms diagnosed with PIMS-TS (Paediatric Inflammatory Multisystem Syndrome – Temporally Associated with SARS-CoV-2) - case report
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A brand new medical condition - 6 years old patient with neurological symptoms diagnosed with PIMS-TS (Paediatric Inflammatory Multisystem Syndrome – Temporally Associated with SARS-CoV-2) - case report

Authors

  • Robert Dubel 1Clinical Hospital No.4, Jaczewskiego Street 8, 20-954 Lublin, Poland https://orcid.org/0000-0001-7666-2893
  • Julia Dubel Medical University of Warsaw, Żwirki i Wigury Street 61, 02-091 Warsaw https://orcid.org/0000-0002-4854-2912
  • Kinga Ruszel Military Clinical Hospital No.1 Al. Racławickie 23, 20-904 Lublin https://orcid.org/0000-0002-9633-4288
  • Aleksandra Czekaj Clinical Frederick Chopin’s Hospital No.1 Fryderyka Szopena 2, 35-055 Rzeszów https://orcid.org/0000-0003-3104-683X
  • Natalia Namroży Clinical Hospital No.4, Jaczewskiego Street 8, 20-954 Lublin, Poland https://orcid.org/0000-0002-7553-4395
  • Magdalena Chrościńska-Krawczyk Department of Paediatric Neurology, Medical University of Lublin, Al. Racławickie 1, 20-059 Lublin https://orcid.org/0000-0001-8121-6580

DOI:

https://doi.org/10.12775/JEHS.2023.13.01.017

Keywords

INFECTIOUS DISEASES, COVID-19, SARS-CoV-2, PIMS-TS

Abstract

Children's multi-system inflammatory syndrome PIMS-TS is a completely new challenge for pediatricians, which has established a separate branch of the fight against the still active COVID-19 pandemic. It turns out that even a pediatric patient who has not suffered symptomatic infection with the SARS-CoV-2 virus, as a result of contact with this pathogen, can develop a severe systemic inflammatory reaction rich in symptoms originating in almost every system of the human body. The first reports of the inflammatory syndrome that is the subject of this work come from May 2020. It is known that the symptoms of PIMS are caused by a multi-system inflammatory response in the body, potentially related to the immune system. The course of this disease may bring to mind other inflammatory diseases in children, such as Kawasaki disease, toxic shock syndrome and MAS macrophage activation syndrome.

References

JCM | Free Full-Text | Presentation, Treatment Response and Short-Term Outcomes in Paediatric Multisystem Inflammatory Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) | HTML [Internet]. [cytowane 30 sierpień 2021]. Dostępne na: https://www.mdpi.com/2077- 0383/9/10/3293/htm

Okarska-Napierała M, Ludwikowska K, Książyk J, Kuchar E, Mazur A, Szenborn L, i in. APPROACH TO A CHILD WITH PAEDIATRIC INFLAMMATORY MULTISYSTEM SYNDROME WITH COVID-19. 49(4):9.

Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, i in. Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA. 21 lipiec 2020;324(3):259–69.

Okarska-Napierała M, Ludwikowska KM, Szenborn L, Dudek N, Mania A, Buda P, i in. Pediatric Inflammatory Multisystem Syndrome (PIMS) Did Occur in Poland during Months with Low COVID-19 Prevalence, Preliminary Results of a Nationwide Register. Journal of Clinical Medicine. listopad 2020;9(11):3386.

Ramcharan T, Nolan O, Lai CY, Prabhu N, Krishnamurthy R, Richter AG, i in. Paediatric Inflammatory Multisystem Syndrome: Temporally Associated with SARS-CoV-2 (PIMS-TS): Cardiac Features, Management and Short-Term Outcomes at a UK Tertiary Paediatric Hospital. Pediatr Cardiol. 1 październik 2020;41(7):1391–401.

Davies P, Evans C, Kanthimathinathan HK, Lillie J, Brierley J, Waters G, i in. Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study. The Lancet Child & Adolescent Health. 1 wrzesień 2020;4(9):669–77.

Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, i in. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1. Arthritis Rheumatol. listopad 2020;72(11):1791–805.

Ahmed M, Advani S, Moreira A, Zoretic S, Martinez J, Chorath K, i in. Multisystem inflammatory syndrome in children: A systematic review. EClinicalMedicine. 4 wrzesień 2020;26:100527.

Simon Junior H, Sakano TMS, Rodrigues RM, Eisencraft AP, Carvalho VEL de, Schvartsman C, i in. Multisystem inflammatory syndrome associated with COVID-19 from the pediatric emergency physician’s point of view. J Pediatr (Rio J). 2021;97(2):140–59.

COVID-19-Paediatric-multisystem- inflammatory syndrome-20200501.pdf [Internet]. [cytowane 30 sierpień 2021]. Dostępne na: https://www.rcpch.ac.uk/sites/default/files/2020-05/COVID-19- Paediatric-multisystem-%20inflammatory%20syndrome-20200501.pdf

ManolisA,ManolisT.PediatricInflammatoryMultisystemSyndromeTemporallyAssociatedWith SARS-Cov-2 Infection (PIMS-TS): Kawasaki-Like Multisystem Inflammatory Syndrome in Children (MIS-C) During the COVID-19 Pandemic with Predominant Myocarditis. 15 lipiec 2020;

Okarska-Napierała M, Ludwikowska K, Książyk J, Kuchar E, Mazur A, Szenborn L, i in. APPROACH TO A CHILD WITH PAEDIATRIC INFLAMMATORY MULTISYSTEM SYNDROME WITH COVID-19. 49(4):9.

PIMS-TS and Kawasaki Disease: The Mystery Deepens : The Pediatric Infectious Disease Journal [Internet]. [cytowane 30 sierpień 2021]. Dostępne na: https://journals.lww.com/pidj/Fulltext/2020/08000/PIMS_TS_and_Kawasaki_Disease__The_Mys tery_Deepens.40.aspx

Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395(10237):1607–8.

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Published

2022-11-25

How to Cite

1.
DUBEL, Robert, DUBEL, Julia, RUSZEL, Kinga, CZEKAJ, Aleksandra, NAMROŻY, Natalia and CHROŚCIŃSKA-KRAWCZYK, Magdalena. A brand new medical condition - 6 years old patient with neurological symptoms diagnosed with PIMS-TS (Paediatric Inflammatory Multisystem Syndrome – Temporally Associated with SARS-CoV-2) - case report. Journal of Education, Health and Sport. Online. 25 November 2022. Vol. 13, no. 1, pp. 105-111. [Accessed 14 May 2025]. DOI 10.12775/JEHS.2023.13.01.017.
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Issue

Vol. 13 No. 1 (2023)

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Short Articles

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Copyright (c) 2022 Robert Dubel, Julia Dubel, Kinga Ruszel, Aleksandra Czekaj, Natalia Namroży, Magdalena Chrościńska-Krawczyk

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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