Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

The use of the GLP-1 analog - dulaglutide in the treatment of morbid obesity - case report
  • Home
  • /
  • The use of the GLP-1 analog - dulaglutide in the treatment of morbid obesity - case report
  1. Home /
  2. Archives /
  3. Vol. 13 No. 1 (2023) /
  4. Articles

The use of the GLP-1 analog - dulaglutide in the treatment of morbid obesity - case report

Authors

  • Agata Juda Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0003-3583-7305
  • Kornelia Rojek Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0002-5096-1235
  • Magdalena Kamińska https://orcid.org/0000-0002-7624-4146
  • Adam Strzoda Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0002-1928-2664
  • Agnieszka Polak Uniwersytet Medyczny w Lublinie https://orcid.org/0000-0003-1694-4738

DOI:

https://doi.org/10.12775/JEHS.2023.13.01.023

Keywords

obesity, dulaglutide, acromegaly, weight reduction

Abstract

Obesity is a disease that is diagnosed in an increasing number of people around the world. Its development is influenced by many factors, both environmental and genetic. It leads to the development of further diseases, thus contributing to a reduction in life expectancy. There are many methods used to treat overweight and obesity. The most important element of the therapeutic process is a reduced diet and physical activity. However, it is often not sufficient, therefore it is becoming more and more common to introduce pharmacotherapy into treatment. One drug is dulaglutide (Trulicity), a GLP-1 analog with promising results. It was included in the treatment of a 49-year-old patient who was diagnosed with morbid obesity. The patient had been struggling with obesity since childhood, and the previously used methods of weight reduction did not bring satisfactory results. After switching to Trulicity (1.5 mg / 0.5 mL s.c.) taken once a week, it was possible to achieve a significant decrease in body weight and the well-being of the patient. If it is officially registered in the treatment of this disease in the future, there is a chance that the results of therapy will improve in many patients.

References

Bergman RN, Kim SP, Hsu IR, et al. Abdominal Obesity: Role in the Pathophysiology of Metabolic Disease and Cardiovascular Risk. Am J Med. 2007;120(2):S3-S8. doi:10.1016/J.AMJMED.2006.11.012

Mohammed MS, Sendra S, Lloret J, Bosch I. Systems and WBANs for controlling obesity. J Healthc Eng. 2018;2018. doi:10.1155/2018/1564748

Hainer V, Toplak H, Mitrakou A. Treatment modalities of obesity: what fits whom? Diabetes Care. 2008;31 Suppl 2. doi:10.2337/dc08-s265

Umpierrez GE, Pantalone KM, Kwan AYM, Zimmermann AG, Zhang N, Fernández Landó L. Relationship between weight change and glycaemic control in patients with type 2 diabetes receiving once-weekly dulaglutide treatment. Diabetes, Obes Metab. 2016;18(6):615-622. doi:10.1111/dom.12660

Dulaglutide. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; April 10, 2019

Chanson P, Salenave S. (No Title). Published online 2008. doi:10.1186/1750-1172-3-17

Dimopoulou C, Sievers • C, Wittchen • H U, et al. Adverse anthropometric risk profile in biochemically controlled acromegalic patients: comparison with an age-and gender-matched primary care population. Published online 2010. doi:10.1007/s11102-010-0218-7

Caballero B. Humans against Obesity: Who Will Win? Published online 2019. doi:10.1093/advances/nmy055

Aaseth J, Ellefsen S, Alehagen U, Sundfør TM, Alexander J. Diets and drugs for weight loss and health in obesity – An update. Biomed Pharmacother. 2021;140(May):0-2. doi:10.1016/j.biopha.2021.111789

(No Title). Published online 2020. doi:10.1210/clinem/dgz330

Heffron SP, Parham JS, Pendse J, Alemán JO. Treatment of Obesity in Mitigating Metabolic Risk. Circ Res. Published online 2020:1646-1665. doi:10.1161/CIRCRESAHA.119.315897

Gurung T, Shyangdan DS, O’Hare JP, Waugh N. A novel, long-acting glucagon-like peptide receptor-agonist: Dulaglutide. Diabetes, Metab Syndr Obes Targets Ther. 2015;8:363-386. doi:10.2147/DMSO.S34418

Filippatos TD, Panagiotopoulou T V, Elisaf MS. DIABETIC STUDIES The Review of Adverse Effects of GLP-1 Receptor Agonists. doi:10.1900/RDS.2014.11.202

Sharma D, Verma S, Vaidya S, Kalia K, Tiwari V. Recent updates on GLP-1 agonists: Current advancements & challenges. Biomed Pharmacother. 2018;108:952-962. doi:10.1016/j.biopha.2018.08.088

Zhao X, Wang M, Wen Z, et al. GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects. doi:10.3389/fendo.2021.721135

Downloads

  • PDF

Published

2022-11-28

How to Cite

1.
JUDA, Agata, ROJEK, Kornelia, KAMIŃSKA, Magdalena, STRZODA, Adam and POLAK, Agnieszka. The use of the GLP-1 analog - dulaglutide in the treatment of morbid obesity - case report. Journal of Education, Health and Sport. Online. 28 November 2022. Vol. 13, no. 1, pp. 146-152. [Accessed 25 May 2025]. DOI 10.12775/JEHS.2023.13.01.023.
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 13 No. 1 (2023)

Section

Articles

License

Copyright (c) 2022 Agata Juda, Kornelia Rojek, Magdalena Kamińska, Adam Strzoda, Agnieszka Polak

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 875
Number of citations: 0

Search

Search

Browse

  • Browse Author Index
  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

obesity, dulaglutide, acromegaly, weight reduction
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop