Features of EEG & HRV in 1997 in humans exposed to the factors of the accident at the Chornobylian nuclear power plant in 1986

Sofiya Ruzhylo; Nataliya Zakalyak; Nataliya Ivanikiv; Dariya Popovych; Xawery Żukow; Igor Popovych

doi:10.12775/JEHS.2022.12.10.025

Authors

Sofiya Ruzhylo Ivan Franko Pedagogical University, Drohobych https://orcid.org/0000-0003-2944-8821
Nataliya Zakalyak Ivan Franko Pedagogical University, Drohobych https://orcid.org/0000-0002-9550-1961
Nataliya Ivanikiv Ivan Franko Pedagogical University, Drohobych https://orcid.org/0000-0002-1475-9507
Dariya Popovych IY Horbachevs’kyi National Medical University, Ternopil’ https://orcid.org/0000-0002-5142-2057
Xawery Żukow Medical University of Bialystok, Bialystok https://orcid.org/0000-0001-5028-7829
Igor Popovych Bohomolets’ Institute of Physiology of National Academy of Sciences, Kyїv https://orcid.org/0000-0002-5664-5591

DOI:

https://doi.org/10.12775/JEHS.2022.12.10.025

Keywords

EEG, HRV, liquidators of the accident at ChNPP, Truskavets’ Spa

Abstract

Background. The dramatic events of the Russian-Ukrainian war around the Chornobyl’ nuclear power plant (NPP) once again opened up the healed wound inflicted by radionuclides on the human body not only in Ukraine, but also in Belarus and the border regions of Russia. The drama of the situation was further intensified by the events surrounding the Zaporizhzhia NPP. This prompted us to turn to the archive of the Truskavetsian Scientific School of Balneology and process the results of research that, due to certain technical and ethical circumstances, remained unanalyzed. Material and methods. The cohort of observation in 1997 were 19 men and 3 women who were exposed to pathogenic factors of the accident at the Chоrnobylian nuclear power plant during the liquidation of its consequences in 1986. The subject of the study was EEG and HRV parameters. The survey was conducted twice - on admission and after two weeks of rehabilitation at the Truskavets’ Spa. Results. Screening of the registered parameters revealed a pronounced sympathotonic shift of the autonomic balance, as well as a statistically significant deviation from the norm of 18 EEG parameters (increase in 8 and decrease in 10). Under the influence of two-week balneotherapy, 5 increased and 5 decreased EEG parameters normalized, but the remaining abnormal EEG and HRV parameters were resistant to the influence of balneofactors. Conclusion. Neurophysiological disorders, detected even 11 years after the effects of the factors of the Chornobyl’ disaster, differ both in severity and sensitivity to the sanogenic effect of the adaptogenic factors of the Truskavets’ Spa.

References

Alyeksyeyev OI, Radysyuk MI, Shymonko IT. Radiation. Sanatorium-Resort Rehabilitation [in Ukrainian]. Kyїv. Naukova dumka; 1995: 94.

Alyeksyeyev OI, Popovych IL, Panassyuk YM, Barylyak LG, Sarancha SM, Shumakov MF. Adaptogens and radiation [in Ukrainian]. Kyїv. Naukova dumka; 1996: 126.

Baevskiy RM, Ivanov GG. Heart Rate Variability: theoretical aspects and possibilities of clinical application [in Russian]. Ultrazvukovaya i funktsionalnaya diagnostika. 2001; 3: 106-127.

Balanovs’kyi VP, Popovych IL, Karpynets’(Ruzhylo) SV. About ambivalence-equilibratory character of influence of curative water Naftussya on organism of human [in Ukrainian]. Dopovidi ANU. Mat Pryr Tekhn Nauky. 1993; 3: 154-158.

Biryukov A, Gorsky A, Ivanov S, Ivanov V, Maksioutov M, Meskikh N, Pitkevitch V, Rastopchin E, Souchkevitch G, Tsyb A. Low doses of ionizing radiation: health effects and assessment of radiation risks for emergency workers of the Chernobyl accident. Ed. by GN Souchkevitch & MN Repacholi. Geneva. World Health Organization; 2001: 242.

Chebotaryova LL. An analysis of sympathetic skin evoked potentials in ptients with nervous system lesions due to the effect of small doses of ionizing radiation [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 161-181.

Chen WC, Chang LH, Huang SS, Huang YJ, Chih CL, Kuo HC, Lee YH, Lee IH. Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain. J Neuroinflamm. 2019; 16: 187.

Chernobyl Disaster (editor VG Baryakhtar) [in Ukrainian]. Kyїv. Naukova dumka; 1995: 559.

Dats’ko OR, Bubnyak AB, Ivassivka SV. The organic part in mineral water Naftussya. Development of knowledges about its composition and origination [in Ukrainian]. Medical Hydrology and Rehabilitation. 2008; 6(1): 168-174.

Esser C, Rannug A. The aryl hydrocarbon receptor in barrier organ physiology, immunology, and toxicology. Pharmacol Rev. 2015; 67(2): 259-279.

Fajda OI, Hrinchenko BV, Snihur OV, Barylyak LG, Zukow W. What Kerdoe’s Vegetative Index really reflects? Journal of Education, Health and Sport. 2015; 5(12): 279-288.

Flyunt IS, Popovych IL, Chebanenko LO, Chaplya MM, Bilas VR. Chornobyl’, Immunity, Kidneys [in Ukrainian]. Kyїv. Computerpress; 2001: 210.

Gozhenko AI. Essays on disease theory [in Russian]. Odesa; 2010: 24.

Gozhenko АІ, Korda MM, Popadynets’ OO, Popovych IL. Entropy, Harmony, Synchronization and Their Neuro-Endocrine-Immune Correlates [in Ukrainian]. Odesa. Feniks; 2021: 232.

Gunko N, Loganovsky K, Buzunov V, Korotkova N. Aging and mental health of the Chornobyl catastrophe survivors. European Psychiatry. 2022; 65(S1): S593-S593.

Heart Rate Variability. Standards of Measurement, Physiological Interpretation, and Clinical Use. Task Force of ESC and NASPE. Circulation. 1996; 93(5): 1043-1065.

Ivassivka SV. Biologically Active Substances of Naftussya Water, their Genesis and Mechanisms of Physiological Action [in Ukrainian]. Kyїv. Naukova dumka; 1997: 110.

Ivassivka SV, Bubnyak AB, Kovbasnyuk ММ, Popovych IL. Genesis and role of phenols in waters from Naftussya layer [in Ukrainian]. In: Problems of pathology in experiment and clinic. Scientific works of Drohobych Medical Institute. Vol XV. Drohobych. 1994: 6-11.

Ivassivka SV, Kovbasnyuk MM, Bubnyak AB, Sovyak DG. Monitoring of the activity of the autochthonous microflora of the Naftussya water of the Truskavets’ field and its relationship with the organic factors of this water and the intensity of precipitation [in Ukrainian]. Medical hydrology and rehabilitation. 2010; 8(2): 57-78.

Kerdö I. Ein aus Daten der Blutzirkulation kalkulierter Index zur Beurteilung der vegetativen Tonuslage. Acta Neurovegetativa (Wien). 1966; 29(2): 250-268.

Kharchenko AP. Electric activity of the brain in persons who suffered from the Chernobyl disaster [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 150-160.

Kimura E, Tohyama C. Embryonic and Postnatal Expression of Aryl Hydrocarbon Receptor mRNA in Mouse Brain. Front Neuroanat. 2017; 11: 4.

Kostyuk PG, Popovych IL, Іvassivka SV (Editors). Chornobyl’, Adaptive and Defensive Systems, Rehabilitation [in Ukrainian]. Kyїv. Computerpress; 2006: 348.

Loganovsky KN, Chuprovskaya NYu, Antipchuk EYu, Bomko MA, Loganovskaja TK, Denisyuk NV, Zdorenko LL, Kravchenko VI, Drozdova NV, Vasilenko ZL, Yukhimenko YeN, Rossokha AP. Diagnostics and treatment of organic mental disorders in persons exposed to ionizing radiation as a result of the Chernobyl accident [in Ukrainian]. Ukrainian Medical Journal. 2005; 3(47): 69-75.

Loganovsky KN, Yuryev KL. EEG patterns in persons exposed to ionizing radiation as a result of the Chernobyl accident. Part 1: conventional EEG analysis. J Neuropsychiatry Clin Neurosci. 2001; 13(4): 441–458.

Loganovsky KN, Yuryev KL. EEG patterns in persons exposed to ionizing radiation as a result of the Chernobyl accident. Part 2: quantitative EEG analysis in patients who had acute radiation sickness. J Neuropsychiatry Clin Neurosci. 2004; 16(1): 70–82.

Loganovsky KN, Masiuk SV, Buzunov VA, Marazziti D, Voychulene YS. Radiation Risk Analysis of Neuropsychiatric Disorders in Ukrainian Chornobyl Catastrophe Liquidators. Frontiers in Psychiatry. 2020; 11: 553420.

Loganovsky K, Marazziti D. Mental Health and Neuropsychiatric Aftermath 35 Years After the Chernobyl Catastrophe: Current State and Future Perspectives. Clinical Neuropsychiatry. 2021; 18(2): 101-106.

Loganovsky K, Fedirko P, Marazziti D, Loganovskaja T, Kuts K, Perchuk I, Babenko T, Antypchuk K, Kreinis G. Radiation-associated cerebroophtalmic effects. European Psychiatry. 2022; 65(S1): S289-S289.

Murray IA, Perdew GH. How Ah receptor ligand specificity became important in understanding its physiological function. Int J Mol Sci. 2020; 21(24): 9614.

Nosov AT, Shamayev MI, Rasheyeva IG. Morphological changes in the brain [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 22-46.

Nyagu AI, Loganovsky KN, Chuprovskaya NYu, Kostyuchenko VG, Vaschenko EA, Yuryev KL, Zazymko RN, Loganovskaya TK, Myschanchuk NS. Nervous system. In: A Vozianov, V Bebeshko, D Bazyka (Eds). Health Effects of Chornobyl Accident. Kyїv. DIA; 2003: 143–176.

Polishchuk ME, Zozulia IS. Peculiarities of cerebrovascular pathology [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 167-171.

Popova IYu, Stepanenko IV, Likhachova TA. Neurological symptomatology and adaptative possibilities of persons who suffered from radiation due to the Chernobyl disaster [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 116-126.

Popovych AI. Features of the neurotropic effects of partial components of the balneotherapeutic complex of spa Truskavets’. Journal of Education, Health and Sport. 2019; 9(1): 396-409.

Popovych IL. Similarity effects of two types of adaptogens (transcutaneous electrical stimulation with the device “VEB” ® and using of bioactive Naftussya water) on the human body. Journal of Education, Health and Sport. 2022; 12(4): 213-258.

Popovych IL, Flyunt IS, Nishcheta IV et al. General Adaptive Reactions and Resistance of the Organism of Liquidators of the Chornobyl’ Accident [in Ukrainian]. Kyїv. Computerpress; 2000: 117.

Popovych IL, Flyunt IS, Alyeksyeyev OI, Barylyak LG, Bilas VR. Sanogenetic Bases of Rehabilitation on Spa Truskavets’ Urological Patients from Chornobylian Contingent [in Ukrainian]. Kyїv. Computerpress; 2003: 192.

Popovych IL, Lukovych YuS, Korolyshyn TA, Barylyak LG, Kovalska LB, Zukow W. Relationship between the parameters heart rate variability and background EEG activity in healthy men. Journal of Health Sciences. 2013; 3(4): 217-240.

Popovych IL, Kozyavkina OV, Kozyavkina NV, Korolyshyn TA, Lukovych YuS, Barylyak LG. Correlation between Indices of the Heart Rate Variability and Parameters of Ongoing EEG in Patients Suffering from Chronic Renal Pathology. Neurophysiology. 2014; 46(2): 139-148.

Popovych IL, Vis’tak (Markevych) HI, Humega MD, Ruzhylo SV. Vegetotropic Effects of Bioactive Water Naftussya and their Neuroendocrine-Immune, Metabolic and Hemodynamic Accompaniments [in Ukrainian]. Kyiv. UNESCO-SOCIO; 2014: 162.

Popovych IL, Gozhenko AI, Korda MM, Klishch IM, Popovych DV, Zukow W (editors). Mineral Waters, Metabolism, Neuro-Endocrine-Immune Complex. Odesa. Feniks; 2022: 252.

Romodanov AP. Status of the brain during internal radiation by small doses and chronic radiation sickness [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 5-17.

Ruzhylo SV, Fihura OA, Zukow W, Popovych IL. Immediate neurotropic effects of Ukrainian phytocomposition. Journal of Education, Health and Sport. 2015; 5(4): 415-427.

Ruzhylo SV, Popovych AI, Zakalyak NR, Chopyk RV, Fihura OA, Bilas VR, Badiuk NS, Gozhenko AI, Popovych IL, Zukow W. Bioactive water Naftussya and ozokerite have the same neuro-endocrine-immune effects in male rats caused by aryl hydrocarnons. PharmacologyOnLine. 2021; 3: 213-226.

Vinnitsky OR. Postradiation encephalopathy [in Ukrainian and Russian]. In: Post-radiation encephalopathy. Experimental studies and clinical observations. (Editor Romodanov AP). Kyїv. USRI of Neurosurgery; 1993: 100-116.

Shannon CE. A mathematical theory of information. Bell Syst Tech J. 1948; 27: 379-423.

Wang X, Hawkins BT, Miller DS. Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. FASEB J. 2011; 25: 644–652.

Wilder JF. Stimulus and Response: the Low of Initial Value. Bristol. J Wright&Sons Ltd; 1967: 352.

Winkelmann T, Thayer JF, Pohlak ST, Nees F, Grimm O, Flor H. Structural brain correlates of heart rate variability in healthy young adult population. Brain Structure and Function. 2017; 222(2): 1061-1068.

Features of EEG & HRV in 1997 in humans exposed to the factors of the accident at the Chornobylian nuclear power plant in 1986

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