Ramsay Hunt syndrome
DOI:
https://doi.org/10.12775/JEHS.2022.12.09.101Keywords
ramsay-hunt sydnrome, herpes, varicella-zosterAbstract
Ramsay-Hunt syndrome (RHS) is a disease caused by reactivation of varicella-zoster virus in the geniculate ganglion. It may be one of the common reasons of the facial palsy. Symptoms of the RHS include vesicular rash on the auricle, external auditory canal, soft palate, pharynx, facial nerve paralysis, ear pain, tinnitus, vertigo and hearing loss. There may be other symptoms connected to cranial nerves (CN) V, VIII, IX or X, when they are involved. Men are more likely to develop lesions than women. Risk of developing Ramsay-Hunt syndrome increases with age. Authors searched Google Scholar and PubMed, using searchterms Ramsay-Hunt syndrome, varicella-zoster virus, VZV, facial palsy. We manually searched the references of selected articles for additional relevant articles. We selected articles relevant to a general medicine readership and prioritised systematic reviews, clinical practice guidelines and cases. The literature contains the latest reports on Ramsay-Hunt syndrome. Clinicians should not ignore patients’ symptoms and always pay attention to possibility of VZV infection and the development of RHS, as treatment should be started within 72 hours after the onset of the symptoms. Main treatment includes antiviral drugs and corticosteroids. The results are promising.
References
Lee J, Choi BY, Noh H, Jeong H, Shin JE, Kim CH. Nystagmus in Ramsay Hunt syndrome with or without dizziness. Neurol Sci. 2021;42(1):193–8.
Gaudencio M, Bertão MI, Carvalho A, Pena G, Bessa I, Gonçalves A. Ramsay Hunt Syndrome in a Patient with Ulcerative Colitis Treated with Infliximab. Eur J Case Reports Intern Med. 2021;3–6.
Zainine R, Sellami M, Charfeddine A, Beltaief N, Sahtout S, Besbes G. Ramsay Hunt syndrome. Eur Ann Otorhinolaryngol Head Neck Dis. 2012;129(1):22–5.
Shim HJ, Jung H, Park DC, Lee JH, Yeo SG. Ramsay Hunt syndrome with multicranial nerve involvement. Acta Otolaryngol. 2011;131(2):210–5.
Uscategui T, Doree C, Chamberlain I, Burton M. Antiviral therapy for Ramsay Hunt syndrome (herpes zoster oticus with facial palsy) in adults (Review). Cochrane Database Syst Rev. 2008;(4):1–11.
Wagner G, Klinge H, Sachse MM. Ramsay Hunt syndrome. JDDG - J Ger Soc Dermatology. 2012;10(4):238–44.
Sweeney C, Gilden D. Ramsay Hunt syndrome. J Neurol Neurosurg Psychiatry. 2001;71:149–54.
Walther LE, Prosowsky K, Walther A, Gudziol H. Herpes Zoster Oticus: Symptom Constellation and Serological Diagnosis. Laryngo-Rhino-Otologie. 2004;83:355–62.
Robillard RB, Hilsinger RL, Adour KK. Ramsay Hunt facial paralysis: Clinical analyses of 185 patients. Otolaryngol - Head Neck Surg. 1986;95(3 I):292–7.
Woo CJ, Chou OHI, Cheung BMY. Ramsay Hunt syndrome following COVID-19 vaccination. Postgrad Med J. 2022;postgradmedj-2021-141022.
Eberhard P, Tillmann T. Zur Epidemiologie der Varizella-Zoster-Infektion. Der Hautarzt. 1996;47(8):604–9.
Nahm FS, Kim SH, Kim HS, Shin JW, Yoo SH, Yoon MH, Lee DI, Lee YW, Lee JH, Jeon YH, Jo DH. Survey on the treatment of postherpetic neuralgia in korea; multicenter study of 1,414 patients. Korean J Pain. 2013;26(1):21–6.
Kunitomo K. Ramsay Hunt syndrome. Postgrad Med J. 2020;96(1133):168.
Hato N, Kisaki H, Honda N, Gyo K, Murakami S, Yanagihara N. Ramsay Hunt syndrome in children. Ann Neurol. 2000;48(2):254–6.
Saniasiaya J. Hypoacusis in Ramsay hunt syndrome: A hidden culprit. Postgrad Med J. 2020;0(0):2020.
Choi JW, Nahm H, Shin JE, Kim CH. Atypical clinical manifestations of herpes zoster oticus: diagnostic usefulness of magnetic resonance imaging. J Neurovirol. 2019;25(6):874–82.
Elliott KJ. Other neurological complications of herpes zoster and their management. Ann Neurol. 1994;35(1 S):S57–61.
Kim YH, Chang MY, Jung HH, Park YS, Lee SH, Lee JH, Oh SH, Chang SO, Koo JW. Prognosis of ramsay hunt syndrome presenting as cranial polyneuropathy. Laryngoscope. 2010;120(11):2270–6.
Yi HA, Lee H. Simultaneous occurrence of trigeminal herpes zoster and Ramsay Hunt syndrome presenting sudden prolonged vertigo. Neurol Sci. 2017;38(11):2049–51.
Byun H, Cho YS, Jang JY, Chung KW, Hwang S, Chung WH, Hong SH. Value of electroneurography as a prognostic indicator for recovery in acute severe inflammatory facial paralysis: A prospective study of bell’s palsy and ramsay hunt syndrome. Laryngoscope. 2013;123(10):2526–32.
Shin DH, Kim BR, Shin JE, Kim CH. Clinical manifestations in patients with herpes zoster oticus. Eur Arch Oto-Rhino-Laryngology. 2016;273(7):1739–43.
Yeo SW, Lee DH, Jun BC, Chang KH, Park YS. Analysis of prognostic factors in Bell’s palsy and Ramsay Hunt syndrome. Auris Nasus Larynx. 2007;34(2):159–64.
Kim CH, Choi H, Shin JE. Characteristics of hearing loss in patients with herpes zoster oticus. Med (United States). 2016;95(46):1–5.
Montague SJ, Morton AR. Ramsay Hunt syndrome. Cmaj. 2017;189(8):E320.
Nishizawa T, Ishikawa K, Matsuo T, Higuchi N, Ishiguro K, Mori N. Atypical Ramsay Hunt syndrome (zoster sine herpete) with otitis media. J Gen Fam Med. 2021;22(6):344–6.
De Ru JA, Van Benthem PPG. Combination therapy is preferable for patients with ramsay hunt syndrome. Otol Neurotol. 2011;32(5):852–5.
Kang HM, Jung SY, Byun JY, Park MS, Yeo SG. Steroid plus antiviral treatment for bell’s palsy. J Intern Med. 2015;277(5):532–9.
Furuta Y, Ohtani F, Mesuda Y, Fukuda S, Inuyama Y. Early diagnosis of zoster sine herpete and antiviral therapy for the treatment of facial palsy. Neurology. 2000;55(5):708–10.
Kinishi M, Amatsu M, Mohri M, Saito M, Hasegawa T, Hasegawa S. Acyclovir improves recovery rate of facial nerve palsy in Ramsay Hunt syndrome. Auris Nasus Larynx. 2001;28(3):223–6.
Giralt Sampedro I, Carvajal G, García-Janeras A, Fabà A, Nishishinya Aquino MB. A severe case of Ramsay Hunt Syndrome treated with acupuncture and related techniques. Complement Ther Clin Pract. 2020;39(October 2019).
Gupta NM, Parikh MP, Panginikkod S, Gopalakrishnan V. Ramsay hunt syndrome. QJM An Int J Med. 2016;109(10):693.
Khan YMT, Fatema N. Ramsay hunt syndrome. Pan Afr Med J. 2019;34:8688.
Pradhan RR. Ramsay Hunt syndrome. IDCases. 2020;21:e00850.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Michał Perszke, Dominika Egierska
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 525
Number of citations: 0