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Journal of Education, Health and Sport

Resveratrol impacts health in patients with diabetes mellitus and other metabolic conditions
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  • Resveratrol impacts health in patients with diabetes mellitus and other metabolic conditions
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  3. Vol. 12 No. 11 (2022) /
  4. Review Articles

Resveratrol impacts health in patients with diabetes mellitus and other metabolic conditions

Authors

  • Emilia Nowak Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0001-7879-6318
  • Dominika Psiuk Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0003-3319-3489
  • Agata Rocka Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0003-4738-3160
  • Natalia Dycha Faculty of Pharmacy, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0002-5212-7463
  • Patryk Jasielski Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0002-0958-735X
  • Faustyna Jasielska Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0002-8280-498X
  • Dominika Madras Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0002-1777-4403
  • Ewelina Rocka Faculty of Medical Denistry, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin https://orcid.org/0000-0002-0767-4863

DOI:

https://doi.org/10.12775/JEHS.2022.12.11.045

Keywords

resveratrol, diabetes, metabolism

Abstract

Background

Resveratrol is a polyphenol with many properties, including activity against glycation, oxidative stress, inflammation, neurodegeneration, carcinogenesis and aging. It appears to be a promising compound for the prevention and treatment of metabolic diseases. The aim of this review is to summarize the results of the latest clinical trials that concern effects of resveratrol in diabetes mellitus type 1 and 2 and its complications - diabetic foot ulcers, diabetic nephropathy and non-alcoholic fatty liver disease.

 

Aim of the study

Based on in vitro studies and animal models, it has been observed that resveratrol reverses the factors causing premature death: obesity, hypertension, and hyperlipidemia. Because of its anti-inflammatory, antioxidant, cardioprotective and blood lowering glucose effects, it appears to be a promising compound for the treatment of metabolic conditions. The review presents different clinical trials concerning the efficiency of resveratrol supplementation in patients with diabetes mellitus and metabolic syndrome and their complications. Most studies focused on assessing the effect of resveratrol supplementation as an adjunctive treatment of diabetes mellitus type 2 and in this group of patients it gave the best results causing reduction of fasting glucose levels, fasting insulin concentration, insulin resistance and improvement of insulin sensitivity and lipid profiles.

 

Conclusions

Resveratrol remains a potential drug in the treatment of metabolic diseases like diabetes mellitus. However, the results of the conducted trials are inconscient. More research is needed to confirm the effectiveness of resveratrol supplementation in treating diabetes, its complications and other metabolic conditions.

References

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Published

2022-11-08

How to Cite

1.
NOWAK, Emilia, PSIUK, Dominika, ROCKA, Agata, DYCHA, Natalia, JASIELSKI, Patryk, JASIELSKA, Faustyna, MADRAS, Dominika & ROCKA, Ewelina. Resveratrol impacts health in patients with diabetes mellitus and other metabolic conditions. Journal of Education, Health and Sport [online]. 8 November 2022, T. 12, nr 11, s. 341–346. [accessed 31.3.2023]. DOI 10.12775/JEHS.2022.12.11.045.
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Vol. 12 No. 11 (2022)

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Review Articles

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Copyright (c) 2022 Emilia Nowak, Dominika Psiuk, Agata Rocka, Natalia Dycha, Patryk Jasielski, Faustyna Jasielska, Dominika Madras, Ewelina Rocka

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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