The influence of drugs used in mental disorders on the health of the oral cavity - a systematic review
DOI:
https://doi.org/10.12775/JEHS.2023.13.01.006Keywords
kserostomia, depresja, antydepresanty, próchnica,, SSRI, TCAAbstract
Ze wzrostem liczby diagnoz zaburzeń psychicznych łączy się wzrost zapotrzebowania na leki psychotropowe, których częstym działaniem niepożądanym jest kserostomia, definiowana jako uczucie suchości w jamie ustnej i prowadząca m.in. do próchnicy i stanów zapalnych błon śluzowych. Największą zdolnością do wywoływania tych działań niepożądanych cechują się leki przeciwpsychotyczne i trójcykliczne leki przeciwdepresyjne, ale nie są od nich wolne także SSRI, antydepresanty atypowe i anksjolityki takie jak benzodiazepiny. W leczeniu kserostomii ważna jest profilaktyka kandydozy i próchnicy: odpowiednia dieta, prawidłowe zabiegi higienizacyjne oraz regularne kontrole stomatologiczne. Inne metody to farmakoterapia i stosowanie substytutów śliny. Istnieje korelacja pomiędzy zaburzeniami psychicznymi a wyższą liczbą ubytków próchnicowych, niższą jakością higieny jamy ustnej i większą częstością występowania chorób periodontologicznych.
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