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Journal of Education, Health and Sport

Non-surgical methods of pain treatment improving the quality of life of patients with endometriosis
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Non-surgical methods of pain treatment improving the quality of life of patients with endometriosis

Authors

  • Jagna Golemo Medical University of Lublin, Faculty of Medicine, Lublin https://orcid.org/0000-0002-2785-858X
  • Anna Gryc Medical University of Lublin, Faculty of Medicine, Lublin https://orcid.org/0000-0002-6258-1168
  • Aleksandra Nowińska Medical University of Lublin, Faculty of Medicine, Lublin https://orcid.org/0000-0002-2235-1130
  • Monika Grudzień Medical University of Lublin, Faculty of Medicine, Lublin https://orcid.org/0000-0002-4855-8308
  • Rafał Świdziński Medical University of Lublin, Faculty of Medicine, Lublin https://orcid.org/0000-0002-8535-0936

DOI:

https://doi.org/10.12775/JEHS.2022.12.12.037

Keywords

endometriosis, hormonal treatment, pain treatment

Abstract

Introduction : Endometriosis is a disease that currently affects 10-15% of women of reproductive age worldwide. The main problem of female patients, in addition to infertility, is pain, which varies greatly, significantly reduces the quality of life and affects family, social, sexual and professional life. Pharmacological treatment, which is applied both after the excision of the lesions and in patients who were not eligible for surgery, is an important element of pain therapy. There are also other methods, such as appropriate diet change, supplementation, acupuncture, electrotherapy, which are partially effective.

Method : review of the recent literature based on PubMEd ,Google scholar research based on the following keywords : endometriosis treatment, hormonal treatment of endometriosis, quality of life of patients with endometriosis

Purpose of work : Comparison of the mode of action and effectiveness of individual non-surgical methods of treating pain in patients with endometriosis.

References

Ahn, S.H.; Singh, V.; Tayade, C. Biomarkers in endometriosis: Challenges and opportunities.Fertil. Steril.2017,107, 523–532

Ribeiro De Carvalho França P, Carolina A, Lontra P, Fernandes PD. molecules Endometriosis: A Disease with Few Direct Treatment Options. 2022; Available from: https://doi.org/10.3390/molecules27134034

Smolarz B, Szyłło K, Romanowicz H. Molecular Sciences Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). 2021; Available from: https://doi.org/10.3390/ijms221910554

Rossi V, Tripodi F, Simonelli C, Galizia R, Nimbi FM. Endometriosis-associated pain: a review of quality of life, sexual health and couple relationship. Minerva Obstet Gynecol. 2021 Oct;73(5):536-552. doi: 10.23736/S2724-606X.21.04781-3. Epub 2021 Apr 27. PMID: 33904688.

Farshi, N.; Hasanpour, S.; Mirghafourvand, M.; Esmaeilpour, K. Effect of Self-Care Counselling on Depression and Anxiety inWomen With Endometriosis: A Randomized Controlled Trial.BMC Psychiatry2020,20, 391

Burney, R.O. Biomarker development in endometriosis.Scand. J. Clin. Lab. Investig. Suppl.2014,244, 75–81. [CrossRef] [PubMed]

Asghari, S.; Valizadeh, A.; Aghebati-Maleki, L.; Nouri, M.; Yousefi, M. Endometriosis: Perspective, lights, and shadows ofetiology.Biomed. Pharm.2018,106, 163–174. [CrossRef]

Berlanda N., Vercellini P., Fedele L.: The outcomes of repeat surgery for recurrent symptomatic endometriosis. Curr. Opin. Obstet. Gynecol., 2010; 22: 320–325.

Louise Jones G, Török P, Morotti M, Barbara G, Buggio L, Facchin F, et al. Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence. 2021; Available from: www.frontiersin.org

Vercellini P, Eskenazi B, Consonni D, et al. Oral contraceptives and risk of endometriosis: A systematic review and meta-analysis. Hum Reprod Update. 2011. https://doi.org/10.1093/humupd/dmq042.

Meresman GF, Augé L, Barañao RI, Lombardi E, Tesone M, Sueldo C. Oral contraceptives suppress cell proliferation and enhance apoptosis of eutopic endometrial tissue from patients with endometriosis. Fertil Steril. 2002;77(6):1141–7. https://doi.org/10.1016/s0015-0282(02)03099-6.

Wu L, Wu Q, Liu L. Oral contraceptive pills for endometrio-sis after conservative surgery: a systematic review and meta-analysis. Gynecol Endocrinol Off J Int Soc Gynecol Endocrinol. 2013;29(10):883–90. https://doi.org/10.3109/09513590.2013.819085

Hee L., Kettner L.O., Vejtorp M.: Continuous use of oral contraceptives: an overview of effects and side-effects. Acta Obstet. Gynecol. Scand., 2013; 92: 125–136.

Dunselman GAJ, Vermeulen N, Becker C, et al. ESHRE guide-line: Management of women with endometriosis. Hum Reprod. 2014. https://doi.org/10.1093/humrep/det457

Barra F, Scala C, Ferrero S. Current understanding on pharma-cokinetics, clinical efficacy and safety of progestins for treat-ing pain associated to endometriosis. Expert Opin Drug Metab Toxicol. 2018;14(4):399–415. https://doi.org/10.1080/17425255.2018.1461840.

1. Vannuccini S, Clemenza S, Rossi M, Petraglia F. Hormonal treatments for endometriosis: The endocrine background. Rev Endocr Metab Disord [Internet]. 1:3. Available from: https://doi.org/10.1007/s11154-021-09666-w

Levine D, Kaufman L, Cuenca VG, Badawy SZA. Cell growth effects of leuprolide on cultured endometrioma cells. J Reprod Med. 2007;52(7):581–4 (PMID: 17847754).

Simoens S., Dunselman G., Dirksen C. i wsp: The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres. Hum. Reprod., 2012; 27: 1292–1299.

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Published

2022-11-21

How to Cite

1.
GOLEMO, Jagna, GRYC, Anna, NOWIŃSKA, Aleksandra, GRUDZIEŃ, Monika and ŚWIDZIŃSKI, Rafał. Non-surgical methods of pain treatment improving the quality of life of patients with endometriosis. Journal of Education, Health and Sport. Online. 21 November 2022. Vol. 12, no. 12, pp. 237-241. [Accessed 20 May 2025]. DOI 10.12775/JEHS.2022.12.12.037.
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Vol. 12 No. 12 (2022)

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Review Articles

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Copyright (c) 2022 Jagna Golemo, Anna Gryc, Aleksandra Nowińska, Monika Grudzień, Rafał Świdziński

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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