Therapeutic potential of Lion's Mane (Hericium erinaceus) in neurological and cognitive disorders - a review of the literature
DOI:
https://doi.org/10.12775/JEHS.2022.12.09.058Keywords
hericum erinaceus, brain, neurological diseasesAbstract
Introduction:
Hericium erinaceus is a medicinal and culinary mushroom that is widely present in the countries of East Asia. Bioactive compounds derived from the fruiting body or its mycelium have many properties, including: antioxidant, antidiabetic, anti-inflammatory, as well as hypolipidemic properties. It also has the potential to treat neurological disorders as it contains neurotrophic compounds that can cross the blood-brain barrier.
Aim of the study: The aim of this work is to review scientific research on the potential properties of the H. erinaceus in treating diseases of the nervous system.
Results: Many studies have shown that Hericium erinaceus can bring the desired effects as a complementary treatment and be an alternative in the treatment of depressive and cognitive disorders and, due to its strong neuroprotective nature, be used in Alzheimer's disease or in post-traumatic brain injury. Most of the cited studies concern experiments carried out on animal models.
Conclusion: Due to the evidence of potentially neuroprotective properties of H. erinaceus, there is a need for further clinical trials in humans.
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Copyright (c) 2022 Tomasz Skubel, Julia Budzyńska, Jakub Czarnota, Michał Dobrzyński, Natalia Rybak, Iga Dudek
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