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Journal of Education, Health and Sport

Ranula as an early symptom of Sjögren’s syndrome
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Ranula as an early symptom of Sjögren’s syndrome

Authors

  • Jakub Aleksandrowicz Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0002-4534-9682
  • Martyna Zielińska Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0001-8886-8274
  • Natalia Zarankiewicz Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0001-9203-3376
  • Julia Kuchnicka Szpital Specjalistyczny w Brzezinach https://orcid.org/0000-0003-0409-5695
  • Katarzyna Kosz Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0001-6848-0598
  • Aleksandra Kuchnicka Absolwent Uniwersytetu Medycznego w Lublinie https://orcid.org/0000-0001-8481-7592
  • Klaudia Sapuła Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie https://orcid.org/0000-0003-2436-0150
  • Klaudia Remjasz Absolwent Warszawskiego Uniwersytetu Medycznego https://orcid.org/0000-0002-0879-7515
  • Wojciech Siedlecki 1 Wojskowy Szpital Kliniczny w Lublinie https://orcid.org/0000-0002-9917-5411
  • Mateusz Fabiś https://orcid.org/0000-0002-7150-1852

DOI:

https://doi.org/10.12775/JEHS.2022.12.09.001

Keywords

Sjogren’s syndrome, Ranula, Mucocele, early diagnosis

Abstract

Introduction and purpose: 

Sjögren's syndrome is an autoimmune disease affecting exocrine glands, mainly salivary glands. A ranula is a type of retention cyst associated with salivary extravasation that develops within the large salivary glands. The most common reason of developing ranula is trauma of bottom of the oral cavity. Damaging the sublingual gland, due to changes in Sjögren’s syndrome, may lead to the development of ranula. The aim of this review is to analyze the possible impact of ranulas on early diagnosis of Sjögren's syndrome.

Material and method:

This review was based on articles collected in PubMed and published in the years 2003-2021 and books from 2009 and 2018. Articles were chosen using keywords such as "Sjögren's syndrome", "ranula", “mucocele” and "early diagnosis".

Results:

Ranulas are considered to be early clinical signs of Sjögren's syndrome. Undergoing diagnostic imaging in patients with ranulas allows to diagnose Sjögren's syndrome in early stage and implement appropriate therapy.

Conclusion:

Identification of ranula should suggest implementation of diagnostics of Sjögren's syndrome using imaging methods such as magnetic resonance imaging or ultrasonography. Early diagnosis of Sjögren's syndrome is crucial to start the adequate treatment and get better results. It is recommended to include imaging tests in the diagnostic criteria of adolescent and adult SS in order to facilitate the diagnosis at an earlier stage of the disease.

References

Kawalec W, Grenda R, Kulus M, Pediatria II, Wydanie II, Warszawa, Anna Plewa, 2018, ISBN 978-83-200-5582-5

Behrbohm H, Kaschke O, Nawka T, Swift A. Ear, Nose, and Throat Diseases With Head and Neck Surgery, 3rd English edition, Stuttgart, Georg Thieme Verlag KG, 2009, ISBN 978-3-13-671203-0

Huzaifa M, Soni A. Mucocele And Ranula. 2021 Feb 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021

Baurmash HD. Mucoceles and ranulas. J Oral Maxillofac Surg. 2003; 61(3):369-78. DOI: 10.1053/joms.2003.50074

Carlini V, Calcaterra V, Pasqua N, Guazzotti M, Fusillo M, Pelizzo G. Plunging Ranula in Children: Case Report and Literature Review. Pediatr Rep . 2016;8:6576. DOI: 10.4081/pr.2016.6576

Mínguez-Martinez I, Bonet-Coloma C, Ata-Ali-Mahmud J, Carrillo-García C, Peñarrocha-Diago M, Peñarrocha-Diago M. Clinical characteristics, treatment, and evolution of 89 mucoceles in children. J Oral Maxillofac Surg. 2010; 68(10):2468-71. DOI: 10.1016/j.joms.2009.12.038

Wu CW, Kao YH, Chen CM, Hsu HJ, Chen CM, Huang IY. Mucoceles of the oral cavity in pediatric patients. Kaohsiung J Med Sci. 2011; 27(7):276-9. DOI: 10.1016/j.kjms.2010.09.006

Takagi Y, Hashimoto K, Katayama I, Eida S, Sumi M. Juvenile primary Sjögren's syndrome with ranula: is ranula a clinical sign that leads to early detection of Sjögren's syndrome? Oral Radiol. 2021; 37:328–335. DOI: 10.1007/s11282-020-00473-8

Means C, Mark A, Aldape MA, King E. Pediatric primary Sjögren syndrome presenting with bilateral ranulas: a case report and systematic review of the literature. Int J Pediatric Otorhinolaryngol. 2017; 101:11–19. DOI: 10.1016/j.ijporl.2017.07.019

Sato K, Yoshida Y, Sakai K, Shibui T, Hashimoto K, Baba A, et al. Sjögren’s syndrome and ranula development. Oral Dis. 2019; 25:1664–1667. DOI: 10.1111/odi.13130

Lieberman SM, Lu A, McGill MM. Oral lesions as presenting feature of childhood Sjögren syndrome. Int J Pediatr Otorhinolaryngol. 2018; 113:303–304. DOI: 10.1016/j.ijporl.2018.05.007

Pinheiro JB, Tirapelli C, Silva CHLD, Komesu MC, Petean FC, Louzada Junior P, León JE, Motta ACF. Oral Nodular Lesions in Patients with Sjögren's Syndrome: Unusual Oral Implications of a Systemic Disorder. Braz Dent J. 2017; 28:405–412. DOI: 10.1590/0103-6440201601013

Chen N, Zeng D, Su Y. Role of ranulas in early diagnosis of Sjögren’s syndrome: A case report. World J Clin Cases. 2021; 9(20):5701–5708. DOI: 10.12998/wjcc.v9.i20.5701

Tsuboi H, Hagiwara S, Asashima H, Takahashi H, Hirota T, Noma H, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Matsumoto I, Sumida T. Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients. Ann Rheum Dis. 2017; 76:1980–1985. DOI: 10.1136/annrheumdis-2016-210758

Baldini C, Ferro F, Elefante E, Bombardieri S. Biomarkers for Sjögren's syndrome. Biomark Med. 2018; 12:275–286. DOI: 10.2217/bmm-2017-0297

Beckman KA, Luchs J, Milner MS, Ambrus JL Jr. The Potential Role for Early Biomarker Testing as Part of a Modern, Multidisciplinary Approach to Sjögren's Syndrome Diagnosis. Adv Ther. 2017; 34:799–812. DOI: 10.1007/s12325-017-0501-3

Shen L, Suresh L, Lindemann M, Xuan J, Kowal P, Malyavantham K, Ambrus JL Jr. Novel autoantibodies in Sjogren's syndrome. Clin Immunol. 2012; 145:251–255. DOI: 10.1016/j.clim.2012.09.013

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Published

2022-08-26

How to Cite

1.
ALEKSANDROWICZ, Jakub, ZIELIŃSKA, Martyna, ZARANKIEWICZ, Natalia, KUCHNICKA, Julia, KOSZ, Katarzyna, KUCHNICKA, Aleksandra, SAPUŁA, Klaudia, REMJASZ, Klaudia, SIEDLECKI, Wojciech and FABIŚ, Mateusz. Ranula as an early symptom of Sjögren’s syndrome. Journal of Education, Health and Sport. Online. 26 August 2022. Vol. 12, no. 9, pp. 11-19. [Accessed 21 May 2025]. DOI 10.12775/JEHS.2022.12.09.001.
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Vol. 12 No. 9 (2022)

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Review Articles

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Copyright (c) 2022 Jakub Aleksandrowicz, Martyna Zielińska, Natalia Zarankiewicz, Julia Kuchnicka, Katarzyna Kosz, Aleksandra Kuchnicka, Klaudia Sapuła, Klaudia Remjasz, Wojciech Siedlecki, Mateusz Fabiś

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