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Journal of Education, Health and Sport

The rapid course of small cell lung cancer and treatment options - case report
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  3. Vol. 12 No. 8 (2022) /
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The rapid course of small cell lung cancer and treatment options - case report

Authors

  • Aleksandra Łomża 1 Student Research Group at the Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin
  • Anna Rodzajewska 1 Student Research Group at the Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin
  • Magda Kowaleczko 1 Student Research Group at the Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin
  • Łukasz Łaba Student Research Group at the Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin
  • Izabela Chmielewska Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin
  • Janusz Milanowski Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin

DOI:

https://doi.org/10.12775/JEHS.2022.12.08.060

Keywords

small cell lung cancer, treatment, survival outcomes

Abstract

 Small cell lung cancer (SCLC) is a disease with an unfavorable prognosis. Factors contributing to losing prognosis include: systemic disease, many comorbidities, smoking and the patient's low performance status (PS). Early diagnosis and treatment initiation seem to be the most significant in the diagnostic and therapeutic process. However, most of patients are diagnosed in metastatic stage. The basic method of metastatic SCLC treatment is chemotherapy, which, according to the latest research (CASPIAN, IMPower133), can be linked to immunotherapy, which is associated with a major improvement in therapeutic efficiency. We present a case of 64-year-old man with a rapidly progressive course of small cell lung cancer, where the fulminant course of the disease led to death within about one month of the first imaging examinations, equally preventing the initiation of systemic treatment. The presented case shows how important is paying attention to the first symptoms, timely diagnosis of the disease and initiation of effective and targeted therapy in patients with SCLC.

References

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Paz-Ares L, Dvorkin M, Chen Y et al. Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial. Lancet. 2019 Nov 23;394(10212):1929-1939. doi: 10.1016/S0140-6736(19)32222-6.

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Früh M, De Ruysscher D, Popat S, et al. ESMO Guidelines Working Group. Small-cell lung cancer (SCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013; 24 Suppl 6: vi99–v105, doi: 10.1093/annonc/mdt178

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A.-M.C. Dingemans, M. Früh, A. Ardizzoni, et. al. Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up; April 2021, doi :https://doi.org/10.1016/j.annonc.2021.03.207

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Published

2022-08-19

How to Cite

1.
ŁOMŻA, Aleksandra, RODZAJEWSKA, Anna, KOWALECZKO, Magda, ŁABA, Łukasz, CHMIELEWSKA, Izabela and MILANOWSKI, Janusz. The rapid course of small cell lung cancer and treatment options - case report. Journal of Education, Health and Sport. Online. 19 August 2022. Vol. 12, no. 8, pp. 572-579. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2022.12.08.060.
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Issue

Vol. 12 No. 8 (2022)

Section

Case Reports

License

Copyright (c) 2022 Aleksandra Łomża, Anna Rodzajewska, Magda Kowaleczko, Łukasz Łaba, Izabela Chmielewska, Janusz Milanowski

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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