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Journal of Education, Health and Sport

Is there a correlation between vitiligo and hearing loss? - review of the literature
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  • Is there a correlation between vitiligo and hearing loss? - review of the literature
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  3. Vol. 12 No. 7 (2022) /
  4. Review Articles

Is there a correlation between vitiligo and hearing loss? - review of the literature

Authors

  • Barbara Rusinowska Student Research Group at the Chair and Department of Epidemiology and Clinical Research Methodology; Medical University of Lublin https://orcid.org/0000-0002-8207-1042

DOI:

https://doi.org/10.12775/JEHS.2022.12.07.081

Keywords

vitiligo, hearing loss, melanocytes, Waardenburg syndrome, SNHL

Abstract

Vitiligo is the most common cause of hipopigmentation occuring with a frequency of 0.5-2% relying on impairment of melanin production caused by the loss of melanocytes. Melanocytes are observed not only in the skin's epidermis and hair follicles but also in the mucosa, the uvea, mesencephalon and on the structures of inner ear – including the stria vascularis, the cochlea and the dark cell areas in the vestibular organs where they play role in regulation auditory and equilibrium functions. These rationale prompted scientists to study the link between hearing loss and vitiligo. Scientists' opinions are divided in this respect - some of them, as a result of their research, see a possible connection, others do not see a correlation between the two diseases. In this review, we present the latest studies evaluating the correlation of hearing impairment with vitiligo.

References

Bergqvist C, Ezzedine K. Vitiligo: A Review. Dermatology. 2020;236(6):571-592. doi: 10.1159/000506103. Epub 2020 Mar 10. PMID: 32155629.

Maciejewska J. Bielactwo nabyte. Medycyna Praktyczna https://www.mp.pl/pacjent/dermatologia/choroby/chorobyskory/167718,bielactwo-nabyte (18.07.2022)

Vajaitu C, Voiculescu VM, Draghici C, Solomon I, Lupu M. Coexistence of Psoriasis, Vitiligo and Oral Lichen Planus – a New Variant of Multiple Autoimmune Syndrome? Maedica (Bucur). 2018 Dec;13(4):336-339. Greek, Modern. doi: 10.26574/maedica.2018.13.4.336. PMID: 30774735; PMCID: PMC6362885.

Yamaguchi Y, Hearing VJ. Melanocytes and their diseases. Cold Spring Harb Perspect Med. 2014 May 1;4(5):a017046. doi: 10.1101/cshperspect.a017046. PMID: 24789876; PMCID: PMC3996377.

van Beelen ESA, van der Valk WH, de Groot JCMJ, Hensen EF, Locher H, van Benthem PPG. Migration and fate of vestibular melanocytes during the development of the human inner ear. Dev Neurobiol. 2020 Nov;80(11-12):411-432. doi: 10.1002/dneu.22786. Epub 2020 Nov 2. PMID: 33075185; PMCID: PMC7894185.

Moghaddam AY, Sayyah M, Fini EA, Talaee R. Investigation the Relationship between Skin Involvement Severity and Hearing Loss Severity in Vitiligo Patients. Mater Sociomed. 2018 Mar;30(1):29-31. doi: 10.5455/msm.2018.30.29-31. PMID: 29670475; PMCID: PMC5857041.

Ahmed jan N, Mui RK, Masood S. Waardenburg Syndrome. 2022 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32809714.

Khan TA, Safdar CA, Zameer S, Khushdil A. Waardenburg-Shah syndrome (WS type IV): a rare case from Pakistan. Perioper Med (Lond). 2020 Jan 24;9:4. doi: 10.1186/s13741-019-0135-x. PMID: 31998473; PMCID: PMC6979113.

Shelby MV. Waardenburg Syndrome Expression and Penetrance. J Rare Dis Res Treat. 2017;2(6):31-40. Epub 2017 Dec 10. PMID: 30854529; PMCID: PMC6404762.

Katz EL, Harris JE. Translational Research in Vitiligo. Front Immunol. 2021 Mar 2;12:624517. doi: 10.3389/fimmu.2021.624517. PMID: 33737930; PMCID: PMC7962476.

El-Gayyar MA, Helmy ME, Amer ER, Elsaied MA, Gaballah MA. Antimelanocyte Antibodies: A Possible Role in Patients with Vitiligo. Indian J Dermatol. 2020 Jan-Feb;65(1):33-37. doi: 10.4103/ijd.IJD_344_18. PMID: 32029937; PMCID: PMC6986111.

Chen J, Li S, Li C. Mechanisms of melanocyte death in vitiligo. Med Res Rev. 2021 Mar;41(2):1138-1166. doi: 10.1002/med.21754. Epub 2020 Nov 17. PMID: 33200838; PMCID: PMC7983894.

Ingordo V, Cazzaniga S, Raone B, Digiuseppe MD, Musumeci ML, Fai D, Pellegrino M, Pezzarossa E, Di Lernia V, Battarra VC, Sirna R, Patrizi A, Naldi L. Circulating autoantibodies and autoimmune comorbidities in vitiligo patients: a multicenter Italian study. Dermatology. 2014;228(3):240-9. doi: 10.1159/000357807. Epub 2014 Mar 5. PMID: 24603479.

Kroon MW, Kemp EH, Wind BS, Krebbers G, Bos JD, Gawkrodger DJ, Wolkerstorfer A, van der Veen JP, Luiten RM. Melanocyte antigen-specific antibodies cannot be used as markers for recent disease activity in patients with vitiligo. J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1172-5. doi: 10.1111/j.1468-3083.2012.04501.x. Epub 2012 Mar 10. PMID: 22404127.

Prabha N, Arora R, Chhabra N, Jati M, Nagarkar NM. Audiological Abnormalities in Vitiligo Patients: A Hospital-Based Cross-Sectional Study. Int Arch Otorhinolaryngol. 2020 Apr;24(2):e149-e153. doi: 10.1055/s-0039-1696700. Epub 2019 Nov 4. PMID: 32256834; PMCID: PMC6828565.

Ma SH, Ang MD, Chang YT, Dai YX. Association between vitiligo and hearing loss. J Am Acad Dermatol. 2021 Dec;85(6):1465-1472. doi: 10.1016/j.jaad.2020.12.029. Epub 2021 Jan 22. PMID: 33359081.

Li CL, Ma SH, Wu CY, et al. Association between sensorineural hearing loss and vitiligo: a nationwide population-based cohort study. Journal of the European Academy of Dermatology and Venereology : JEADV. 2022 Jul;36(7):1097-1103. DOI: 10.1111/jdv.18047. PMID: 35274365.

Arya R, Kumar Munjal S, Panda NK, Prasad D. Audiological and Electrophysiological Changes in Patients with Vitiligo. Indian J Otolaryngol Head Neck Surg. 2016 Dec;68(4):417-423. doi: 10.1007/s12070-015-0889-5. Epub 2015 Aug 23. PMID: 27833865; PMCID: PMC5083641.

Manno A, Pace A, Iannella G, Rossetti V, Polimeni R, Milani A, Cocuzza S, Maniaci A, Magliulo G. Audiological and vestibular evaluations in vitiligo patients. Bosn J Basic Med Sci. 2022 Feb 1;22(1):140-146. doi: 10.17305/bjbms.2021.5703. PMID: 34374641; PMCID: PMC8860322.

Rahimi H, Mozafari N, Bastaninejad S, Tehranchinia Z, Samani NA. Hearing status in patients with vitiligo. Clin Cosmet Investig Dermatol. 2019 Jun 21;12:445-450. doi: 10.2147/CCID.S201012. PMID: 31296994; PMCID: PMC6596346.

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Published

2022-08-01

How to Cite

1.
RUSINOWSKA, Barbara. Is there a correlation between vitiligo and hearing loss? - review of the literature. Journal of Education, Health and Sport. Online. 1 August 2022. Vol. 12, no. 7, pp. 810-816. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2022.12.07.081.
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Vol. 12 No. 7 (2022)

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Review Articles

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Copyright (c) 2022 Barbara Rusinowska

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