The influence of physical activity on selected biochemical parameters - what do physically active people know about it?
DOI:
https://doi.org/10.12775/JEHS.2022.12.07.094Keywords
physicial activity, knowledge, glucose, insulin, lipid profile, liver function testsAbstract
Introduction and purpose. Physical activity is an integral part of a healthy lifestyle, and the far-reaching benefits of practising it are invaluable. Raising awareness in this regard seems to be a key element in the prevention of civilization diseases. This study aimed to assess the knowledge of amateur athletes about the influence of physical effort on changes in selected biochemical parameters. Material and methods. In the study that was conducted using the questionnaire method and electronically using the proprietary form, one hundred physically active people participated. The survey consisted of single-choice and multiple-choice questions as well as open-ended questions. It collected information on (1) demographic and social characteristics, (2) anthropometric measurements, (3) type and duration of physical activity, (4) frequency and time of the training, (5) existing diseases and (6) knowledge about glucose, insulin, lipid profile, alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase. The key questions concerned the influence of physical activity on the studied biochemical parameters. Results. The vast majority of respondents revealed a good knowledge of insulin and insulin resistance, carbohydrate metabolism and creatine kinase. The average results of correct answers amounted to 90%, 79% and 71%. The knowledge of the issues related to the lipid profile, and both ALT and AST was slightly worse. Here the distribution of the proper answers was respectively 62% and 60%. Conclusions. Properly conducted education on the influence of physical activity on selected biochemical parameters could be the best solution to broaden the knowledge on this subject.
References
Villablanca PA, Alegria JR, Mookadam F. Nonexercise activity thermogenesis in obesity management, Mayo Clin Proceeding, 2015 Apr;90(4):509-19. doi: 10.1016/j.mayocp.2015.02.001.
Pabich M, Materska M. Biological Effect of Soy Isoflavones in the Prevention of Civilization Diseases. Nutrients. 2019 Jul 20;11(7):1660. doi: 10.3390/nu11071660.
Kalbarczyk M, Mackiewicz-Łyziak J. Physical Activity and Healthcare Costs: Projections for Poland in the Context of an Ageing Population. Appl Health Econ Health Policy. 2019 Aug;17(4):523-532. doi: 10.1007/s40258-019-00472-9
Bull FC, Al-Ansari SS, Biddle S. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. British Journal of Sports Medicine 2020;54:1451-1462. doi: 10.1136/bjsports-2020-102955.
Hills AP, Dengel DR, Lubans DR. Supporting public health priorities: recommendations for physical education and physical activity promotion in schools. Prog Cardiovasc Dis. 2015 Jan-Feb;57(4):368-74. doi: 10.1016/j.pcad.2014.09.010.
Jefferies P, Ungar M, Aubertin P, Kriellaars D. Physical literacy and resilience in children and youth. Frontiers in Public Health. 2019;7:349. doi: 10.3389/fpubh.2019.00346.
Strath SJ, Kaminsky LA, Ainsworth BE. : Guide to the assessment of physical activity: Clinical and research applications: a scientific statement from the American Heart Association. Circulation 2013;128 (20): 2259-2279. doi: 10.1161/01.cir.0000435708.67487.da.
Hills AP, Andersen LB, Byrne NM. Physical activity and obesity in children. Br J Sports Med. 2011 Sep;45(11):866-70. doi: 10.1136/bjsports-2011-090199.
Morris JN, Hardman AE. Walking to health. Sports Med. 1997 May;23(5):306-32. doi: 10.2165/00007256-199723050-00004.
Blundell JE, Gibbons C, Caudwell P, Finlayson G, Hopkins M. Appetite control and energy balance: impact of exercise. Obes Rev. 2015 Feb;16 Suppl 1:67-76. doi: 10.1111/obr.12257.
Lee KS, Lee JK, Yeun YR. Effects of a 10-Day Intensive Health Promotion Program Combining Diet and Physical Activity on Body Composition, Physical Fitness, and Blood Factors of Young Adults: A Randomized Pilot Study. Med Sci Monit. 2017 Apr 11;23:1759-1767. doi: 10.12659/msm.900515.
Shahidi SH, Stewart Williams J, Hassani F. Physical activity during COVID-19 quarantine. Acta Paediatr. 2020 Oct;109(10):2147-2148. doi: 10.1111/apa.15420.
Almond L, Whitehead, M (2012). Physical Literacy: Clarifying the Nature of the Concept. Physical Education Matters. 7(1). ISSN 1751-0988
Meyer J, McDowell C, Lansing J, Brower C, Smith L, Tully M. et al. Changes in Physical Activity and Sedentary Behavior in Response to COVID-19 and Their Associations with Mental Health in 3052 US Adults. Int J Environ Res Public Health. 2020 Sep 5;17(18):6469. doi: 10.3390/ijerph17186469.
Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA. 2004 Mar 10;291(10):1238-45. doi: 10.1001/jama.291.10.1238. Erratum in: JAMA. 2005 Jan 19;293(3):298. Erratum in: JAMA. 2005 Jan 19;293(3):293-4.
Ruegsegger GN, Booth FW. Health Benefits of Exercise. Cold Spring Harb Perspect Med. 2018 Jul 2;8(7):a029694. doi: 10.1101/cshperspect.a029694.
Myers J, Prakash M, Froelicher V. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med. 2002 Mar 14;346(11):793-801. doi: 10.1056/NEJMoa011858.
Peluso MA, Guerra de Andrade LH. Physical activity and mental health: the association between exercise and mood. Clinics (Sao Paulo). 2005 Feb;60(1):61-70. doi: 10.1590/s1807-59322005000100012.
Musich S, Wang SS, Hawkins K, Greame C. The Frequency and Health Benefits of Physical Activity for Older Adults. Popul Health Manag. 2017 Jun;20(3):199-207. doi: 10.1089/pop.2016.0071.
Callow DD, Arnold-Nedimala NA, Jordan LS. The Mental Health Benefits of Physical Activity in Older Adults Survive the COVID-19 Pandemic. Am J Geriatr Psychiatry. 2020 Oct;28(10):1046-1057. doi: 10.1016/j.jagp.2020.06.024.
Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020 Dec;54(24):1451-1462. doi: 10.1016/j.jagp.2020.06.024.
Stamatakis E, Gale J, Bauman A, Ekelund U, Hamer M, Ding D. Sitting Time, Physical Activity, and Risk of Mortality in Adults. J Am Coll Cardiol. 2019 Apr 30;73(16):2062-2072. doi: 10.1016/j.jacc.2019.02.031.
Matusiak-Wieczorek E, Lipert A, Kochan E, Jegier A. The time spent sitting does not always mean a low level of physical activity. BMC Public Health. 2020 Mar 12;20(1):317. doi: 10.1186/s12889-020-8396-3.
U.S. Department of Health and Human Services.Physical Activity Guidelines Advisory Committee Scientific Report Washington, DC: US Department of Health and Human Services; 2018. https://health.gov/sites/default/files/2019-09/PAG_Advisory_Committee_Report.pdf
Miko HC, Zillmann N, Ring-Dimitriou S, Dorner TE, Titze S, Bauer R. Auswirkungen von Bewegung auf die Gesundheit [Effects of Physical Activity on Health]. Gesundheitswesen. 2020 Sep;82(S 03):S184-S195. German. doi: 10.1055/a-1217-0549.
Palacios G, Pedrero-Chamizo R, Palacios N. EXERNET Study Group. Biomarkers of physical activity and exercise. Nutr Hosp. 2015 Feb 26;31 Suppl 3:237-44. doi: 10.3305/nh.2015.31.sup3.8771.
Global report on Diabetes, WHO, 2016, http://www.who.int/diabetes/global-report/en/, download of the day15.08. 2021, ISBN: 9789241565257
Alvim RO, Cheuhen MR, Machado SR, Sousa AG, Santos PC. General aspects of muscle glucose uptake. An Acad Bras Cienc. 2015 Mar;87(1):351-68. doi: 10.1590/0001-3765201520140225.
Evans PL, McMillin SL, Weyrauch LA, Witczak CA. Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training. Nutrients. 2019 Oct 12;11(10):2432. doi: 10.3390/nu11102432.
Kadoglou NP, Iliadis F, Angelopoulou N. The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus. Eur J Cardiovasc Prev Rehabil. 2007 Dec;14(6):837-43. doi: 10.1097/HJR.0b013e3282efaf50.
Pan B, Ge L, Xun YQ. Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. Int J Behav Nutr Phys Act. 2018 Jul 25;15(1):72. doi: 10.1186/s12966-018-0703-3.
Jorge ML, de Oliveira VN, Resende NM. The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus. Metabolism. 2011 Sep;60(9):1244-52. doi: 10.1016/j.metabol.2011.01.006.
Arora E, Shenoy S, Sandhu JS. Effects of resistance training on metabolic profile of adults with type 2 diabetes. Indian J Med Res. 2009 May;129(5):515-9.
Bacchi E, Negri C, Zanolin ME. Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects: a randomized controlled trial (the RAED2 study). Diabetes Care. 2012 Apr;35(4):676-82. doi: 10.2337/dc11-1655. Epub 2012 Feb 16.
Freeman AM, Pennings N. Insulin Resistance. 2020 Jul 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–.
Ferrari F, Bock PM, Motta MT, Helal L. Biochemical and Molecular Mechanisms of Glucose Uptake Stimulated by Physical Exercise in Insulin Resistance State: Role of Inflammation. Arq Bras Cardiol. 2019 Dec;113(6):1139-1148. doi: 10.5935/abc.20190224.
Petersen MC, Shulman GI. Mechanisms of Insulin Action and Insulin Resistance. Physiol Rev. 2018 Oct 1;98(4):2133-2223. doi: 10.1152/physrev.00063.2017.
Bessa A, Nissenbaum M, Monteiro A, Gandra PG. High-intensity ultraendurance promotes early release of muscle injury markers. British Journal of Sports Medicine. 2008 Nov;42(11):889-93. doi: 10.1136/bjsm.2007.043786.
Reidy PT, Mahmassani ZS, McKenzie AI. Influence of Exercise Training on Skeletal Muscle Insulin Resistance in Aging: Spotlight on Muscle Ceramides. Int J Mol Sci. 2020 Feb 22;21(4):1514. doi: 10.3390/ijms21041514.
Roberts CK, Hevener AL, Barnard RJ. Metabolic syndrome and insulin resistance: Underlying causes and modification by exercise training. Compr. Physiol. 2013;3:1–58. doi: 10.1002/cphy.c110062.
Henriksen EJ. Effects of acute exercise and exercise training on insulin resistance. J. Appl. Physiol. 2002;93:788–796. doi: 10.1042/bse0420031.
Zanuso S, Sacchetti M, Sundberg CJ. Exercise in type 2 diabetes: genetic, metabolic and neuromuscular adaptations. A review of the evidence. British Journal of Sports Medicine. 2017 Nov;51(21):1533-1538. doi: 10.1136/bjsports-2016-096724.
Mirabelli M, Russo D, Brunetti A. The Role of Diet on Insulin Sensitivity, Nutrients, 2020, 12[10]:3042. https://doi.org/10.3390/nu12103042
Adeva-Andany M.M. Effect of diet composition on insulin sensitivity in humans, Clinical Nutrition ESPEN, 2019,33:29-38. doi: 10.1016/j.clnesp.2019.05.014.
Gołąbek K.d, Regulka-Ilow B, Dietary suport in insulin resistance: An overview od current scientific reports, ,,Advances in Clinical and Experimental Medicine” 2019,28[11]:1577-1585. doi: 10.17219/acem/109976.
Pownall HJ, Gotto AM Jr. Cholesterol: Can't Live With It, Can't Live Without It. Methodist Debakey Cardiovasc J. 2019 Jan-Mar;15(1):9-15. doi: 10.14797/mdcj-15-1-9.
Tosheska Trajkovska K, Topuzovska S. High-density lipoprotein metabolism and reverse cholesterol transport: strategies for raising HDL cholesterol. Anatol J Cardiol. 2017 Aug;18(2):149-154. doi: 10.14744/AnatolJCardiol.2017.7608.
Zdrojewski T, Jankowski P, Bandosz P. Nowa wersja systemu oceny ryzyka sercowo-naczyniowego i tablic SCORE dla populacji Polski [A new version of cardiovascular risk assessment system and risk charts calibrated for Polish population]. Kardiol Pol. 2015;73(10):958-61. doi: 10.5603/KP.2015.0182
2016 European Guidelines on cardiovascular di sease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts): Developed with the special contribution of the European Association for Cardiovascular Prevention and Rehabilitation (EACPR). Eur. He art J. 2016;37(29):2315–2381. doi: 10.1093/eurheartj/ehw106
Catapano A.L, Graham I, De Backer G. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias: The Task Force for the Manage ment of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atheroscle rosis Society (EAS) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur. Heart J. 2016. doi: 10.1016/j.atherosclerosis.2016.08.018.
Chapman MJ, Ginsberg HN, Amarenco P. European Atherosclerosis Society Consensus Panel. Triglyceride rich lipoproteins and high density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J. 2011;32:1345–1361. doi: 10.1093/eurheartj/ehr112.
Cartier LJ, Collins C, Lagace M, Douville P. Comparison of fasting and non fasting lipid profiles in a large cohort of patients presenting at a community hospi tal. Clin Biochem. 2018;52: 61–66. doi: 10.1016/j.clinbiochem.2017.11.007.
Kraus WE, Houmard JA, Duscha BD, Knetzger KJ, Wharton MB, McCartney JS et al. Effects of the amo unt and intensity of exercise on plasma lipoproteins. N Engl J Med. 2002;347:1483–1492. doi: 10.1056/NEJMoa020194.
Maeda K, Noguchi Y, Fukui T. The effects of cessation from cigarette smo king on the lipid and lipoprotein profiles: a meta analysis. Prev Med. 2003;37:283–290. doi: 10.1016/s0091-7435(03)00110-5.
Sabatine MS. Advances in the treatment of dyslipidemia. Cleve Clin J Med. 2016 Mar;83(3):181-6. doi: 10.3949/ccjm.83gr.16001.
Shaw K, Gennat H, O’Rourke P, Del Mar C. Exercise for overweight or obesi ty. Cochrane Database Syst Rev. 2006;4:CD003817. doi: 10.1002/14651858.CD003817.pub3.
Huffman KM, Hawk VH, Henes ST, Ocampo CI, Orenduff MC, Slentz CA et al. Exercise effects on lipids in persons with varying dietary patterns does diet matter if they exercise? Respon ses in studies of a targeted risk reduction intervention through defined exercise I. Am Heart J. 2012;164:117–124. doi: 10.1016/j.ahj.2012.04.014.
Brien SE, Ronksley PE, Turner BJ, Mukamal KJ, Ghali WA. Effect of alcohol consumption on biological markers associated with risk of coronary heart dise ase: systematic review and meta analysis of interventional studies. BMJ. 2011;342:d636. doi: 10.1136/bmj.d636.
Liu Z, Que S, Xu J, Peng T. Alanine aminotransferase-old biomarker and new concept: a review. Int J Med Sci. 2014 Jun 26;11(9):925-35. doi: 10.7150/ijms.8951
Mena P, Maynar M, Campillo JE. Changes in plasma enzyme activities in professional racing cyclists, British Journal of Sports Medicine 1996;30:122-124. doi: 10.1136/bjsm.30.2.122.
Sierra AP, Oliveira RA, Silva ED, Lima GHO. O-51 Influence of power genotype score on muscle injury after endurance exercise, British Journal of Sports Medicine 2016(50):A29-A30. doi: 10.1007/s00421-016-3411-1.
Nesic D, Suzic-Lazic J, Djuric B. P-81 Nutritional status better correlates with aminotransferase levels in female athletes British Journal of Sports Medicine 2016;50:A76-A77. doi: 10.1136/bjsports-2016-097120.134.
Smart NA, King N, McFarlane JR, Graham PL, Dieberg G. Effect of exercise training on liver function in adults who are overweight or exhibit fatty liver disease: a systematic review and meta-analysis. British Journal of Sports Medicine. 2018 Jul;52(13):834-843. doi: 10.1136/bjsports-2016-096197.
Malarz I, Wrześniewski K, Basiaga-Pasternak J. Selected psychological determinants of physical activity among women with metabolic syndrome, JKES 2018;28(84):45-50. doi: 10.5604/01.3001.0013.7811
Hickman I, Jonsson J, Prins J, Ash S, Purdie D, Clouston A et al. Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life. Gut. 2004;53(3):413–419. doi: 10.1136/gut.2003.027581.
Baba CS, Alexander G, Kalyani B. Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis. Journal of gastroenterology and hepatology. 2006;21(1):191–198. doi: 10.1111/j.1440-1746.2005.04233.x.
Brancaccio P, Maffulli N, Limongelli FM. Creatine kinase monitoring in sport medicine. Br. Med. Bull. 2007;81–82:209–230. doi: 10.1093/bmb/ldm014.
Moghadam-Kia S, Oddis CV, Aggarwal R. Approach to asymptomatic creatine kinase elevation. Cleve Clin J Med. 2016 Jan;83(1):37-42. doi: 10.3949/ccjm.83a.14120.
Lilleng H, Abeler K, Johnsen SH. Variation of serum creatine kinase (CK) levels and prevalence of persistent hyperCKemia in a Norwegian normal population. The Tromsø Study. Neuromuscul Disord. 2011 Jul;21(7):494-500. doi: 10.1016/j.nmd.2011.04.007.
Rumley AG, Pettigrew AR, Colgan ME. Serum lactate dehydrogenase and creatine kinase during marathon training. British Journal of Sports Medicine.. 1985 Sep;19(3):152-155. doi:10.1136/bjsm.19.3.152
Koch AJ, Pereira R, Machado M. The creatine kinase response to resistance exercise. J Musculoskelet Neuronal Interact. 2014 Mar;14(1):68-77. PMID: 24583542.
Pedersen ES, Tengesdal S, Radtke M, Langlo KAR. Major increase in creatine kinase after intensive exercise. Tidsskr Nor Laegeforen. 2019 Apr 8;139(7). doi: 10.4045/tidsskr.18.0120.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Arleta Grzesznik, Dorota Formanowicz
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 333
Number of citations: 0