Neurological and neuropsychological post-covid complications
DOI:
https://doi.org/10.12775/JEHS.2022.12.07.045Keywords
postcovid neurological symptoms, neurological complications, COVID-19Abstract
Introduction: COVID-19 is an acute respiratory disease caused by the SARS-CoV-2 virus. It attacks the respiratory system in particular, however, it can also lead to gastrointestinal or neurological diseases. The disease leads to numerous neurological complications.
Material and method: the purpose of this study is to review the neurological and neuropsychological complications that have arisen as a result of COVID-19 outbreak. The literature available on the PubMed scientific platform was reviewed. Time descriptors were set for 2020-2022.
Results: Neurological symptoms are mainly due to cerebral hypoxia due to respiratory failure. These include encephalitis, meningitis, encephalopathies, seizures, disorders of consciousness, smell, taste and vision, among others. Neuropsychological complications can also occur.
Conclusions: Pulmonary abnormalities, neurological complications and exercise intolerance were frequently identified complications among COVID-19 survivors. The main neurological symptoms reported were fatigue, concentration changes, memory loss, and sleep disturbances. In contrast, the longest-lasting complications were fatigue, loss of concentration or memory, weakness, pain and dizziness.
Keywords: "COVID-19", "postcovid neurological symptoms", "neurological complications".
References
Ahmad I, Rathore FA. Neurological manifestations and complications of COVID-19: A literature review. J Clin Neurosci. 2020;77:8-12. doi:10.1016/j.jocn.2020.05.017
Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019.N Engl J Med. 2020;382(8):727-733. doi:10.1056/NEJMoa2001017
Niazkar HR, Zibaee B, Nasimi A, Bahri N. The neurological manifestations of COVID-19: a review article. Neurol Sci. 2020;41(7):1667-1671. doi:10.1007/s10072-020-04486-3
Chen X, Laurent S, Onur OA, et al. A systematic review of neurological symptoms and complications of COVID-19. J Neurol. 2021;268(2):392-402. doi:10.1007/s00415-020-10067-3
Mao L, Jin H, Wang M, et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683-690. doi:10.1001/jamaneurol.2020.1127
Ellul M, Solomon T. Acute encephalitis - diagnosis and management. Clin Med (London). 2018 Mar;18(2):155-159. doi: 10.7861/clinmedicine.18-2-155. PMID: 29626021; PMCID: PMC6303463. DOI: 10.7861/clinmedicine.18-2-155
Xiang P., Xu X.M., Gao L.L., Wang H.Z., Xiong H.F., Li R.H. First case of 2019 novel coronavirus disease with Encephalitis. ChinaXiv. 2020;T202003:00015.
Roy D, Ghosh R, Dubey S, Dubey MJ, Benito-León J, Kanti Ray B. Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic. Can J Neurol Sci. 2021 Jan;48(1):9-24. doi: 10.1017/cjn.2020.173. Epub 2020 Aug 5. PMID: 32753076; PMCID: PMC7533477.
Moriguchi T, Harii N, Goto J, et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. Int J Infect Dis. 2020;94:55-58. doi:10.1016/j.ijid.2020.03.062
Duong L, Xu P, Liu A. Meningoencephalitis without respiratory failure in a young female patient with COVID-19 infection in Downtown Los Angeles, early April 2020.Brain Behav Immun. 2020;87:33. doi:10.1016/j.bbi.2020.04.024
Li Y, Li M, Wang M, Zhou Y, Chang J, Xian Y, Wang D, Mao L, Jin H, Hu B. Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study. Stroke Vasc Neurol. 2020 Sep;5(3):279-284. doi: 10.1136/svn-2020-000431. epub 2020 Jul 2. PMID: 32616524; PMCID: PMC7371480.
Lahiri D, Ardila A. COVID-19 Pandemic: A Neurological Perspective. Cureus. 2020 Apr 29;12(4):e7889. doi: 10.7759/cureus.7889. PMID: 32489743; PMCID: PMC7255551.
Camargo-Martínez W, Lozada-Martínez I, Escobar-Collazos A, Navarro-Coronado A, Moscote-Salazar L, Pacheco-Hernández A, Janjua T, Bosque-Varela P. Post-COVID 19 neurological syndrome: Implications for sequelae's treatment. J Clin Neurosci. 2021 Jun;88:219-225. doi: 10.1016/j.jocn.2021.04.001. epub 2021 Apr 8. PMID: 33992187; PMCID: PMC8031003.
Asadi-Pooya AA. Seizures associated with coronavirus infections. Seizure. 2020 Jul;79:49-52. doi: 10.1016/j.seizure.2020.05.005. Epub 2020 May 11. PMID: 32416567; PMCID: PMC7212943.
Butowt R, von Bartheld CS. Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection. Neuroscientist. 2021 Dec;27(6):582-603. doi: 10.1177/1073858420956905. epub 2020 Sep 11. PMID: 32914699; PMCID: PMC7488171.
Elhiny R, Al-Jumaili AA , Yawuz MJ . What might COVID-19 Patients Experience after Recovery? A Systematic Review. Authorea. June 17, 2021.
Halpin SJ, McIvor C, Whyatt G, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. Journal of medical virology . 2021;93(2):1013-1022.
Sarkisian L, Saaby L, Poulsen TS, Gerke O, Jangaard N, Hosbond S, Diederichsen AC, Thygesen K, Mickley H. Clinical Characteristics and Outcomes of Patients with Myocardial Infarction, Myocardial Injury, and Nonelevated Troponins. Am J Med. 2016 Apr;129(4):446.e5-446.e21
Zhong P, Xu J, Yang D, Shen Y, Wang L, Feng Y, Du C, Song Y, Wu C, Hu X, Sun Y. COVID-19-associated gastrointestinal and liver injury: clinical features and potential mechanisms. Signal Transduct Target Ther. 2020 Nov 2;5(1):256.
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Copyright (c) 2022 Katarzyna Mielniczek, Aleksandra Kowalska , Katarzyna Jóźwik, Marta Lipiec, Diana Dołomisiewicz
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