How to treat acne in women with polycystic ovary syndrome (PCOS)? Review of the available literature
DOI:
https://doi.org/10.12775/JEHS.2022.12.06.017Keywords
acne vulgaris, polycystic ovary syndrome, hyperandrogenism, hormone replacement therapy, combined oral contraceptive pillAbstract
Acne vulgaris is one of the most common chronic skin diseases among people between 15 and 40 years of age.[i] It would seem that it is a typical disease of adolescence. However, it also very often affects adults. One of the most common causes of acne vulgaris in adult women is polycystic ovary syndrome (PCOS). The hyperandrogenism and metabolic disorders present in this syndrome may contribute to the formation of blackheads, pimples, and cysts on the face, chest and back. This article focuses on a review of current acne treatments associated with polycystic ovary syndrome.
[i] Stern RS. Medication and medical service utilization for acne 1995-1998. J Am Acad Dermatol 2000; 43: 1042-1048
References
Stern RS. Medication and medical service utilization for acne 1995-1998. J Am Acad Dermatol 2000; 43: 1042-1048
Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;8:41. [PMC free article] [PubMed] [Google Scholar]
Azziz R, Woods KS, Reyna R, et al. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 89(6):2745-9 (2004 Jun)
Chang WY, Knochenhauer ES, Bartolucci AA, et al. Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups. Fertil Steril 83(6):1717-23 (2005 Jun).
Gollnick HP, Dreno B. Pathophysiology and management of acne. J Eur Acad Dermatol Venereol. 2015;29(suppl 4):1–2. [PubMed] [Google Scholar]
Karrer-Voegeli S, Rey F, Reymond MJ, et al. Androgen dependence of hirsutism, acne, and alopecia in women: retrospective analysis of 228 patients investigated for hyperandrogenism. Medicine (Baltimore) 88(1):32-45 (2009 Jan)
group TREA-sPcw Revised 2003 consensus on diagnostic criteria and longterm health risks related to polycystic ovary syndrome (PCOS) Hum Reprod. 2003;10(1):41–47. [PubMed] [Google Scholar]
Carmina E and Lobo RA (2001) Polycystic ovaries in hirsute women with normal menses. Am J Med 111,602–606.
Diagnosis and treatment of polycystic ovary syndrome: an endocrine society clinical practice guideline. Legro RS, Arslanian SA, Ehrmann DA, et al. J Clin Endocrinol Metab. 2013;98:4565–4592. [PMC free article] [PubMed] [Google Scholar] [Ref list]
Cardiometabolic and reproductive benefits of early dietary energy restriction and voluntary exercise in an obese PCOS-prone rodent model. Diane A, Kupreeva M, Borthwick F, Proctor SD, Pierce WD, Vine DF. J Endocrinol. 2015;226:193–206. [PubMed] [Google Scholar] [Ref list]
Lakshmi C. Hormone therapy in acne. Indian J Dermatol Venereol Leprol. 2013;79:322–337. [PubMed] [Google Scholar] [Ref list]
Husein-ElAhmed H. Management of acne vulgaris with hormonal therapies in adult female patients. Dermatol Ther. 2015;28(3):166–172. [PubMed] [Google Scholar] [Ref list]
Bubna AK. Metformin – for the dermatologist. Indian J Pharmacol. 2016;48(1):4–10. [PMC free article] [PubMed] [Google Scholar] [Ref list]
Layton AM. Top ten list of clinical pearls in the treatment of acne vulgaris. Dermatol Clin. 2016;34(2):147–157. [PubMed] [Google Scholar] [Ref list]
Lowenstein EJ. Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome. Dermatol Ther. 2006;19(4):210–223. [PubMed] [Google Scholar] [Ref list]
Melnik B. The role of transcription factor FoxO1 in the pathogenesis of acne vulgaris and the mode of isotretinoin action. Giornale Italiano Di Dermatologia E Venereologia. 2010;145(5):559–571. doi: 10.1111/j.1365-2133.2010.09754.x. [PubMed] [CrossRef] [Google Scholar] [Ref list]
Karadag A. S., Ertugrul D. T., Tutal E., Akin K. O. Isotretinoin influences pituitary hormone levels in acne patients. Acta Dermato-Venereologica. 2011;91(1):31–34. doi: 10.2340/00015555-1013. [PubMed] [CrossRef] [Google Scholar] [Ref list]
G Acmaz, L Cınar , B Acmaz, H Aksoy, Yusuf Taner Kafadar, Y Madendag, F Ozdemir, E Sahin, I Muderris . The Effects of Oral Isotretinoin in Women with Acne and Polycystic Ovary Syndrome.Biomed Res Int. 2019 Apr 7;2019:2513067. doi: 10.1155/2019/2513067.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Ewelina Zygmunt, Hubert Wróblewski, Aleksandra Zimna, Dariusz Chojęta, Anna Kozłowska
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 209
Number of citations: 0
