Structural functional parameters of the heart in patients with acute myocardial infarction with ST-segment elevation in the presence of pulmonary hypertension
DOI:
https://doi.org/10.12775/JEHS.2022.12.08.009Keywords
acute myocardial infarction, pulmonary hypertension, diastolic dysfunctionAbstract
Introduction: Acute Myocardial Infarction with ST-Segment Elevation (STEMI) is one of the major causes of morbidity and mortality all over the world. Pulmonary hypertension (LH) occurs in various clinical conditions, including diseases of the left half of the heart.
Objective: To evaluate the structural and functional features of the heart in ST-elevated myocardial infarction (STEMI) of the left ventricular wall (LV) in the presence of pulmonary hypertension (PH).
Materials and Methods: The study involved 87 patients (48 men and 37 women) with STEMI who were treated in intensive care and emergency cardiology department of the "City hospital and emergency ambulance" Zaporizhia city council. Patients were divided into two groups: 51 patients with STEMI in the presence of PH (mean age 69,30 ± 2,34 years), 36 patients with STEMI without PH (mean age 65,20 ± 2,02 years).
Results: Evaluation of the structural and functional features of LV showed that in patients with STEMI with PH compared to patients with STEMI without PH there was a significant decrease in EF (by 25.6%; p <0.05), increase in MMILV by 17.6%; p <0.05) and LVDs (by 13.3%; p <0.05). In patients with PH, the diameter of LA was 12.9% higher than in patients without PH (p <0.05).
In the study of LV diastolic function using pulsed Doppler revealed that in patients with STEMI with PH there is a significant acceleration of MVE (by 32,3%; p <0.05) and increasing in the ratio of MV E/A (by 63,4%, p <0,05) compared with patients without PH.
Conclusions: In patients with STEMI pulmonary hypertension develops against the background of dilatation of the left ventricles of the heart with the formation of eccentric hypertrophy and systolic LV dysfunction. In patients with STEMI and PH we found an overload of the right ventricles of the heart with increasing size of the right ventricle and right atrium.
References
V.M. Kovalenko, Sci. E. Lutay, Yu.M.Sirenko. Cardiovascular disease. The classification standards for diagnosis and treatment. K .: Association of Cardiologists of Ukraine. 2016; 128 p. Ukrainian.
Galiè N., Humbert M., Vachiery JL 2015 ESC / ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur. Heart J. 2016; 37: 67-119. doi: 10.1093 / eurheartj / ehv317.
Guazzi M., Borlaug BA Pulmonary Hypertension Due to Left Heart Disease. Circulation. 2012; 125: 975-990. doi: 10.1161 / CIRCULATIONAHA.111.085761.
Ahsan S., Hamed S. The impact of pulmonary hypertension on in-hospital outcomes of non-st elevation myocardial infarction. J. Am. Coll. Cardio. in 2018; 71: 1940. doi: 10.1016 / S0735-1097 (18) 32481-1.
Lang R.M., Badano L.P., Mor-Avi V. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J. Am. Soc. Echocardiogr. 2015; 28: 1-39. doi: 10.1016 / j.echo.2014.10.003.
Nagueh SF, Smiseth OA, Appleton CP Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J. Am. Soc. Echocardiogr. in 2016; 29: 277-314. doi: 10.1016 / j.echo.2016.01.011.
Mehra P., Mehta V., Sukhija R. Pulmonary hypertension in left heart disease. Arch. Med. Sci. in 2019; 15: 262-273. doi: 10.5114 / aoms.2017.68938.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Yaroslav Zemlianiy, Victor Syvolap
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 444
Number of citations: 0
