Autoimmune pituitary inflammation
DOI:
https://doi.org/10.12775/JEHS.2022.12.02.001Keywords
pituitary gland, autoimmune diseases, autoimmune pituitary inflammationAbstract
Autoimmune Hypophysitis (AH) is often refereed in the literature as lymphocytic pituitary inflammation. It is the most common form of rare, chronic inflammation states affecting this gland. In most cases it has autoimmune character. Symptoms of pituitary inflammation are mostly headaches, dysfunction of anterior and/or posterior pituitary lobe and visual disturbances. Diagnostics is extremely difficult and inflammation itself is probably diagnosed too rare. Autoimmune Hypophysitis coexist with other autoimmune endocrinopathies. The golden standard in Autoimmune Hypophysitis diagnosis is biopsy and magnetic resonance imaging (MRI) is also used. In relation to rare occurrence of the Autoimmune Hypophysitis, varied clinical picture and lack of standardized research on large group of patients there are no described standards of conduct with those patients.
References
Joshi MN, Whitelaw BC, Carroll PV. Mechanisms In Endocrinology: Hypophysitis: diagnosis and treatment. Eur J Endocrinol. 2018 Sep;179(3):R151–63.
Bellastella G, Maiorino MI, Bizzarro A, Giugliano D, Esposito K, Bellastella A, et al. Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects. Pituitary. 2016 Dec;19(6):625–42.
Langlois F, Varlamov EV, Fleseriu M. Hypophysitis, the Growing Spectrum of a Rare Pituitary Disease. J Clin Endocrinol Metab. 2022 Jan 1;107(1):10–28.
de Vries F, van Furth WR, Biermasz NR, Pereira AM. Hypophysitis: A comprehensive overview. Presse Médicale. 2021 Dec;50(4):104076.
Caturegli P, Newschaffer C, Olivi A, Pomper MG, Burger PC, Rose NR. Autoimmune Hypophysitis. Endocr Rev. 2005;26(5):599–614.
De Bellis A, Bizzarro A, Bellastella A. Pituitary antibodies and lymphocytic hypophysitis. Best Pract Res Clin Endocrinol Metab. 2005;19(1):67–84.
Hashimoto K, Takao T, Makino S. Lymphocytic adenohypophysitis and lymphocytic infundibuloneurohypophysitis. Endocr J. 1997;44(1):1–10.
Bellastella A, Bizzarro A, Coronella C, Bellastella G, Sinisi AA, De Bellis A. Lymphocytic hypophysitis: a rare or underestimated disease? Eur J Endocrinol. 2003;149(5):363–76.
Cauley K, Dalal A, Olson B, Onyiuke H. Lymphocytic hypophysitis. Conn Med. 2005;69(3):143–6.
Rose NR, Bona C. Defining criteria for autoimmune diseases (Witebsky’s postulates revisited). Immunol Today. 1993;14(9):426–30.
De Bellis A, Bizzarro A, Conte M, Perrino S, Coronella C, Solimeno S, et al. Antipituitary antibodies in adults with apparently idiopathic growth hormone deficiency and in adults with autoimmune endocrine diseases. J Clin Endocrinol Metab. 2003;88(2):650–4.
Nishino M, Yabe S, Murakami M, Kanda T, Kobayashi I. Detection of antipituitary antibodies in patients with autoimmune thyroid disease. Endocr J. 2001;48(2):185–91.
O’Dwyer DT, Clifton V, Hall A, Smith R, Robinson PJ, Crock PA. Pituitary autoantibodies in lymphocytic hypophysitis target both γ- and α-Enolase – a link with pregnancy? Arch Physiol Biochem. 2002;110(1–2):94–8.
Krysiak R, Okopień B, Herman ZS. Zapalenie przysadki mózgowej. Przegląd Lek. 2007;64(515–20):7–8.
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Copyright (c) 2022 Szymon Krzewski, Mateusz Baranowski, Katarzyna Wzorek
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