Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress
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  • Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress

Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress

Authors

  • P. Olekshij Lviv Medical Institute

DOI:

https://doi.org/10.12775/JEHS.2021.11.11.005

Keywords

periodontitis, stress, polymorhonuclear leucocytes, nonspecific resistance

Abstract

The aim of our study was to determine the phagocytic activity of leukocytes and nitrosine tetrazolium test (NST - test) in the dynamics of experimental periodontitis (EP) and immobilization stress (IS). It is established in the work that the indicators studied by us, namely phagocytic number, phagocytic index and NST - test increase on the 3 rd, 5 th and 15 th days of our experiment. The above tests have a high diagnostic value and allow to characterize the degree of activity of the inflammatory process and determine the participation of individual parts of the body's defense mechanisms. The obtained results make it possible to express the opinion that polymorphonuclear leukocytes take an active part in the formation of EP and IS, as well as indicate the stimulation of metabolic processes in leukocytes.

References

Gembitsky EV. Assessment of the immune status of the organism in medical establishments of the Soviet army and navy: Methodical manual. - Central Military Medical Directorate of the USSR Defense Ministry.1987. 114. (in Russian)

Gorizontov PD, Belousov OI, Fedotov MI . Stress i systema krovi. M .: Medicine, 1983.p.338. (in Russian)

Jogan ZR Clinico-experimentalne obosnovanie usovershenstvovania orthopedichnyx metodiv pry complexnomu likuvanni chvorob parodonta. Author's ref. Dis. Candidate of Medical Sciences, Kyiv, 1996. р.18. (in Ukrainian)

Kononova, O. V. (2018). Eksperymentalne obhruntuvannia zastosuvannia adrenoblokatoriv. Sovremennaia stomatolohyia, 2: 86-89 (in Ukrainian).

Kononova, O.V. (2018). Patohistolohichne doslidzhennia vplyvu kompleksu adrenoblokatoriv na reheneratsiiu kistky shchelepy. Sovremennaia stomatolohyia. 3: 36-38 (in Ukrainian).

Arunachalam M, Pulikkotil SJ, Sonia N. Platelet Rich Fibrin in Periodontal Regeneration. The Open Denistry Journal. 2016. (in English).

Dixit S, Doshi Y, Shah MU, Dabholkar CS. Management of chronic generalized periodontitis using diode laser. J Indian Soc Periodontol 2016;20:88- 90. (in English).

Newman, M., Takei, H., Klokkevold, P., & Carranza, F. (2018). Newman and Carranza's Clinical Periodontology, 13th Edition. St. Louis: Saunders, 944 (in English).

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Published

2021-11-10

How to Cite

1.
OLEKSHIJ, P. Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress. Journal of Education, Health and Sport [online]. 10 November 2021, T. 11, nr 11, s. 67–72. [accessed 17.1.2022]. DOI 10.12775/JEHS.2021.11.11.005.

Issue

Vol. 11 No. 11 (2021)

Section

Research Articles

License

Copyright (c) 2021 P. Olekshij

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons non-exclusive license (CC BY-ND 4.0).

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