Dynamics of changes in nonspecific resistance of guinea pigs under conditions of formation of experimental periodontitis and immobilization stress
DOI:
https://doi.org/10.12775/JEHS.2021.11.11.005Keywords
periodontitis, stress, polymorhonuclear leucocytes, nonspecific resistanceAbstract
The aim of our study was to determine the phagocytic activity of leukocytes and nitrosine tetrazolium test (NST - test) in the dynamics of experimental periodontitis (EP) and immobilization stress (IS). It is established in the work that the indicators studied by us, namely phagocytic number, phagocytic index and NST - test increase on the 3 rd, 5 th and 15 th days of our experiment. The above tests have a high diagnostic value and allow to characterize the degree of activity of the inflammatory process and determine the participation of individual parts of the body's defense mechanisms. The obtained results make it possible to express the opinion that polymorphonuclear leukocytes take an active part in the formation of EP and IS, as well as indicate the stimulation of metabolic processes in leukocytes.
References
Gembitsky EV. Assessment of the immune status of the organism in medical establishments of the Soviet army and navy: Methodical manual. - Central Military Medical Directorate of the USSR Defense Ministry.1987. 114. (in Russian)
Gorizontov PD, Belousov OI, Fedotov MI . Stress i systema krovi. M .: Medicine, 1983.p.338. (in Russian)
Jogan ZR Clinico-experimentalne obosnovanie usovershenstvovania orthopedichnyx metodiv pry complexnomu likuvanni chvorob parodonta. Author's ref. Dis. Candidate of Medical Sciences, Kyiv, 1996. р.18. (in Ukrainian)
Kononova, O. V. (2018). Eksperymentalne obhruntuvannia zastosuvannia adrenoblokatoriv. Sovremennaia stomatolohyia, 2: 86-89 (in Ukrainian).
Kononova, O.V. (2018). Patohistolohichne doslidzhennia vplyvu kompleksu adrenoblokatoriv na reheneratsiiu kistky shchelepy. Sovremennaia stomatolohyia. 3: 36-38 (in Ukrainian).
Arunachalam M, Pulikkotil SJ, Sonia N. Platelet Rich Fibrin in Periodontal Regeneration. The Open Denistry Journal. 2016. (in English).
Dixit S, Doshi Y, Shah MU, Dabholkar CS. Management of chronic generalized periodontitis using diode laser. J Indian Soc Periodontol 2016;20:88- 90. (in English).
Newman, M., Takei, H., Klokkevold, P., & Carranza, F. (2018). Newman and Carranza's Clinical Periodontology, 13th Edition. St. Louis: Saunders, 944 (in English).
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