Age changes in the tigroid substance of neutrons of the lateral preoptic nucleus of hypothalamus under different light modes
DOI:
https://doi.org/10.12775/JEHS.2021.11.10.025Keywords
sleep-wake cycle, lateral preoptic nucleus of hypothalamus, circadian rhythms, photoperiodAbstract
The article presents analysis of the results of the original histochemical studies of tigroid substance of neurons of the lateral preoptic nucleus of hypothalamus in mature and old rats under the influence of different light modes. In all observations, the tigroid substance was located in the cytoplasm of neurons of the lateral preoptic nucleus of hypothalamus in the form of individual granular formations of different sizes and shapes. The amount of tigroid substance of neurons of the lateral preoptic nucleus of hypothalamus in mature rats is greater than in older rats. At the same time, it should be noted that different experimental conditions significantly affected the amount of tigroid substance in neurons of the lateral preoptic nucleus of hypothalamus in old rats. In particular, under conditions of light deprivation, the optical density of specific histochemical staining for tigroid substance in neurons of the lateral preoptic nucleus of hypothalamus increased significantly (p<0,001), and under conditions of light stimulation, on the contrary, probably decreased (p<0,001).
References
Flomin YuV. Rasstroystva sna u patsientov s insul'tom: vyyavlenie, klinicheskoe znachenie i sovremennye podkhody k lecheniyu. Mezhdunarodnyy nevrologicheskiy zhurnal. 2014; 1 (63): 89 – 100. [in Russian].
Berdina ON, Madaeva IM, Rychkova LV. Ozhirenie i narusheniya tsirkadnykh ritmov sna i bodrstvovaniya: tochki soprikosnoveniya i perspektivy terapii. Acta biomedica scientifica. 2020; 5 (1): 21-30. [in Russian].
Meira e Cruz M, Laranjo SM, Rocha I. Hypothalamic Control of Sleep-Wake Circadian Cycle [Internet]. In: Baloyannis S, Gordeladze J, editors. Hypothalamus in Health and Diseases. IntechOpen; 2018[cited 2021 Mar 31], p. 31-45. Available from: https://repositorio.ul.pt/bitstream/10451/42504/1/Hypothalamic.pdf doi: 10.5772/intechopen.79899
Kroeger D, Absi G, Gagliardi C, Bandaru SS., Joseph C, et all . Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice. Nature Communications. 2018; 9: 1 -14.
Koval'zon VM, Dolgikh VV. Regulyatsiya tsikla bodrstvovanie–son. Nevrologicheskiy zhurnal. 2016; 6: 316 – 322. [in Russian].
Wahl S, Engelhardt M, Schaupp P, et al. The inner clock – blue light sets the human rhythm. Journal of Biophotonics. 2019; 12 (3): 1 – 14.
Chaulin AM, Duplyakova PD, Duplyakov DV. Tsyrkadnye ritmy serdechnykh tropinov: mekhanizmy i klinicheskoe znachenie. Rossiyskiy kardiologicheskiy zhurnal. 2020; 25 (S3): 62 – 69. [in Russian].
Koval'zon VM, Dorokhov VB. Tsikl bodrstvovanie-son i bioritmy cheloveka pri razlichnykh rezhimakh cheredovaniya svetlogo i temnogo perioda sutok. The journal of scientific articles “Health & education millennium”. 2013; 15 (1-4): 151 – 162. [in Russian].
Dolhov OM. Na dopomohu studenta. Nervova tkanyna. Vinnytsia; 2016. 44 s. [in Ukrainian].
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