Influence balneotherapy on spa Truskavets’ with taking Canephron® N on urina lithogenicity and its metabolic and neuroendocrine-immune accompaniments in patients with chronic pyelonephrite and cholecystite
Keywordslithogenicity of urina, EEG, HRV, immunity, spa Truskavets’, Canephron® N.
Shulyak Oleksandr V., Flyunt Igor-Severyn S., Flyunt Victor R., Fil’ Vitaliǐ M., Hrinchenko Borys V., Snihur Oleh V., Zukow Walery, Yanchiy Oksana R., Popovych Igor L. Influence balneotherapy on spa Truskavets’ with taking Canephron® N on urina lithogenicity and its metabolic and neuroendocrine-immune accompaniments in patients with chronic pyelonephrite and cholecystite. Journal of Education, Health and Sport. 2015;5(11):453-465. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.34351
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This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
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Received: 25.09.2015. Revised 25.10.2015. Accepted: 24.11.2015.
INFLUENCE BALNEOTHERAPY ON SPA TRUSKAVETS’ WITH TAKING CANEPHRON® N ON URINA LITHOGENICITY AND ITS METABOLIC AND NEUROENDOCRINE-IMMUNE ACCOMPANIMENTS IN PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE
Oleksandr V. Shulyak1, Igor-Severyn S. Flyunt2, Victor R. Flyunt3,6, Vitaliǐ M. Fil’2,
Borys V. Hrinchenko3, Oleh V. Snihur3, Walery Zukow4, Oksana R. Yanchiy5, Igor L. Popovych6
1Scientic Reseach Institute of Urology, Kyiv, Ukraine Avshulyak@yandex.ua
2Faculties of Biology and Physical Education, Ivan Franko Pedagogical University, Drohobych, Ukraine
3JSC “Dnipro-Beskyd”, Truskavets’, Ukraine firstname.lastname@example.org
4Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland email@example.com
5Departament of Biology, OO Bohomolets’ National Medical University, Kyiv, Ukraine
6Laboratory of Balneology, OO Bohomolets’ Institute of Physiology NAS, Truskavets’-Kyiv, Ukraine
Objective. We know that balneotherapy on spa Truskavets' did not significantly affect the parameters of urina Lithogenicity, including Ca/Mg ratio, so search for means of reducing urina Lithogenicity remains relevant. We also know that Phytopreparation Canephron® N recommended for inclusion in complex therapy of chronic pyelonephrite as effective elimination of infectious kidney inflammation, prevention of recurrence of inflammation and lithogenese. Aim: to find out the possibility of reducing urina Lithogenicity influenced balneotherapy on spa Truskavets' by additional taking Canephron® N. Results. Standardized balneotherapy not significantly affect urina Lithogenicity in patients with chronic pyelonephrite and cholecystite, even showed a trend to increase, while additional use Canephron® N significantly reduces urina Lithogenicity by reducing the concentration of Uric acid and downward trend Calcium. Reducing urina Lithogenicity accompanied by a decrease urina concentration Chloride and Potassium, and Baevskiy’s Activity Regulatory Systems Index, Asymmetry δ-, θ- and α-rhythms of background EEG and α-rhythm normalized Power Spectrum Density (PSD) in right loci Fp2, F8, T6 and O2, while HRV markers of vagal tone (RMSSD, pNN50, TI) also Frequency Deviation θ- and β-rhythms, Amplitude β- and δ-rhythms, δ-rhythm PSD in loci Fp2, F8, T3, T5, O1, O2, β-rhythm PSD in loci Fp1, F4 and θ-rhythm PSD in loci T3 and F7 rising. However, Canephron® N preventes or reverses increasing Uric acid plasma level, Mineralocorticoide Activity, Sympathetic tone, Baevskiy’s Stress Index and PSD ULF HRV also decreasing PSD VLF HRV. Concerning parameters of Immunity Canephron® N decreases blood level active T-Lymphocytes but increases level B-Lymphocytes, Stubnucleary Neutrophiles and total Leukocytes also prevents or reverses increasing CD16+ NK-Lymphocytes, CD8+ and Theophilinesensitive T-Lymphocytes, Monocytes and serum IgM also decreasing CD4+ T-Lymphocytes and Neutrophiles Phagocytose Count vs Staphylococcus aureus. In addition, Canephron® N potentiates increasing Parathyrine Activity, serum level IgG and Bactericidic Capacity of Neutrophiles vs Staphylococcus aureus also decreasing Urea and Creatinine plasma level, Sodium urina concentration and Neutrophiles Phagocytose Count vs Escherichia coli. Conclusion. Introduce Canephron® N into standard balneotherapeutic complex spa Truskavets’ contribute to decrease urina Lithogenicity accompanied by decreasing of HRV and EEG markers of chronic Stress and favorable modulation parameters of Immunity in patients with chronic pyelonephrite and cholecystite.
Keywords: lithogenicity of urina, EEG, HRV, immunity, spa Truskavets’, Canephron® N.
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