Peculiarities of changes in indices of immunological reactivity in experimental allergic alveolitis under adrenalin myocardial injury and their correction with thiotriazoline

Abstract

Pyndus Volodymyr. Peculiarities of changes in indices of immunological reactivity in experimental allergic alveolitis under adrenalin myocardial injury and their correction with thiotriazoline = Особливості змін показників імунологічної реактивності при експериментальному алергічному альвеоліті в умовах адреналінового пошкодження міокарда та їх корекція тіотриазоліном. Journal of Education, Health and Sport. 2015;5(10):185-190. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.32603

http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2810%29%3A185-190

https://pbn.nauka.gov.pl/works/661368

Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive

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© The Author (s) 2015;

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This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial

use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 05.08.2015. Revised 05.09.2015. Accepted: 20.10.2015.

UDK 616.24 – 056.2 – 082.8

Peculiarities of changes in indices of immunological reactivity in experimental allergic alveolitis under adrenalin myocardial injury and their correction with Thiotriazoline

Особливості змін показників імунологічної реактивності при експериментальному алергічному альвеоліті в умовах адреналінового пошкодження міокарда та їх корекція тіотриазоліном

Volodymyr Pyndus

В. Б. Пандус

Danylo Halytsky Lviv National Medical University, Lviv, Ukraine

Львівський національний медичний університет ім. Данила Галицького,

м. Львів, Україна

Abstract

Allergic diseases cover more than 20% of people living on the earth, among who exogenous allergic alveolitis (AA) occupies a prominent place. However, the frequency of this disease increases and there is a number of complications with not only medical but also socio-economic values. Today the question remains to be not studied that concerns changes of selected indicators of clinical and humoral immunity in the blood for experimental allergic alveoli (EAA) and adrenaline myocardial injury (AMI) and the possibility of their correction with antioxidants. The goal of study was to elucidate peculiarities of changes of immunological reactivity in the EAA in terms of AMI and set the effect of  thiotriazoline on them. The study of individual markers of cellular and humoral immunity showed a malfunction of the immune system in the formation of EAA and AMI and set monocristalline the effect of thiotriazolin on the level of T and B-lymphocytes and  CIC in blood.

Key words: experimental allergic alveolitis, adrenaline myocardial injury, thiotriazolin.

Ключові слова: експериментальний алергічний альвеоліт, адреналінове пошкодження міокарда, тіотриазолін.