Possible mechanisms of daylight duration and frequency of endometrium hyperplasia development

Abstract

Chumak Z. V., Zelinsky A. A., Shapoval N. V. Possible mechanisms of daylight duration and frequency of endometrium hyperplasia development. Journal of Education, Health and Sport. 2017;7(1):449-459. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.293055

http://ojs.ukw.edu.pl/index.php/johs/article/view/4274

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754 Journal of Education, Health and Sport eISSN 2391-8306 7

© The Author (s) 2017;

This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland

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(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017.

POSSIBLE MECHANISMS  OF DAYLIGHT DURATION AND FREQUENCY OF ENDOMETRIUM HYPERPLASIA DEVELOPMENT

Z. V. Chumak², A. A. Zelinsky¹, N. V. Shapoval¹

¹Odessa National Medical University

²Odessa Municipal Centre for Menopause Problems

nymba@mail.ru

Summary

The objective: to learn correlation of daylight duration and frequency of endometrium proliferous processes development. Retrospective analysis of case histories, patients’ histological journals with pathologically verified diagnosis of endometrium proliferous processes have been analyzed. All the patients referred to  the clinics of the 5^th maternity house at 2011-2014. The following groups were formed: hyperplasia of endometrium - simple complex hyperplasia without atypia; atypical hyperplasia of endometrium- simple complex hyperplasia with atypia; polyps of endometrium; adenocarcinoma. At the comparison of the daylight mean duration and frequency of proliferation atypical forms the instability between the parameters under study has been revealed. Comparison of the real levels of melatonin secretion at day and night time, mean duration of the daylight and frequency of endometrium’s proliferation show the presence of a hidden correlation at the condition of different statistical models of mathematical processing of the data use.

Key words: pineal gland, melatonin, hyperplasia of endometrium, biological rhythm, proliferation.