Structural and functional changes in the kidneys of rats with toxic nephropathy after a course of drinking mineral water «DONAT Mg»
DOI:
https://doi.org/10.12775/JEHS.2022.12.10.044Keywords
toxic nephropathy, kidney disease, glomerulonephritis, mineral water «Donat Mg»Abstract
Kidney disease of various etiologies affects 6-7% of the total population of the globe. Glomerulonephritis and nephropathy of various etiologies make up a significant part of these kidney lesions. Infectious and non-infectious glomerulonephritis and nephropathy are distinguished, the latter are associated with the influence of environmental factors, including toxic substances, heavy metals and even medications.
Magnesium is considered one of the components of the body's stress-limiting system, since all its effects are aimed at reducing the manifestations of stress and normalizing adaptation processes.
A comparative assessment of changes in the kidneys during the simulation of toxic nephropathy and the influence of magnesium-containing agents on the course of the pathology of the experimental model was carried out.
References
Chronic kidney disease and the global NCDs agenda / B. L. Neuen, S. J. Chadban, A. R. Demaio, et al. BMJ Glob Health. 2017. Vol. 2, № 2. e000380.
Chapter 9: Infection-related glomerulonephritis. Kidney Int Suppl (2011). 2012. Vol. 2 (2). P. 200–208.
Cunningham M. W. Pathogenesis of group A streptococcal infections. Clin Microbiol Rev. 2000. Vol. 13, № 3. Р. 470–511.
Konrad M., Schlingmann K. P., Gudermann T. Insights into the molecular nature of magnesium homeostasis. Am J Physiol Renal Physiol. 2004. Vol. 286 (4). Р. 599–605.
Pavlyuk N. M., Badyuk N. S., Vasyuk V. L. Influence of magnesium-containing compounds on the function of kidney rates with the model of toxic glomerulonephritis // Bulletin of Marine Medicine. 2020. №4 (89). – P. 116-119
Pavlyuk N. M., Badіuk N. S., Gushcha S. G. The state of the functional activity of the central nervous system and peripheral blood and the possibility of correcting their disorders with magnesium preparations // Actual problems of transport medicine / 2021;1(63):113-120.
Magnesium Status and Stress: The Vicious Circle Concept Revisited / G. Pickering, А. Mazur, М. Trousselard, et al. Nutrients 2020. № 12. Article namber 3672.
Pavliuk N. N., Gushcha S. G., Badiuk N. S. The effect of changes in magnesium metabolism on the structural and functional state of the kidneys during stress-induced endogenous intoxication. / Actual problems of transport medicine / 2020;3(61):120-126.
Pavlyuk N. M., Badіuk N. S., Gushcha S. G. Comparative evaluation of the effect of magnesium-containing preparations of different chemical composition on kidney function in animals with experimental toxic glomerulonephritis // Bulletin of Marine Medicine. 2021. №1 (90)., 68-73.
Pavliuk N. M., Badiuk N. S. The influence of magnesium preparations on the change in metabolism in the modeling of toxic nephropathy in animals. // Journal of Education, Health and Sport. 2022;12(6):403-409.
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