Impact of Exercise on the Course of Dermatomyositis: A Narrative Review of Recent Studies

Abstract

Introduction and Purpose: Dermatomyositis (DM) is a rare autoimmune inflammatory myopathy characterized by muscle weakness and distinctive skin manifestations, impacting both children and adults. This narrative review aims to examine the latest studies assessing the impact of physical activity on the course of dermatomyositis and determine which forms of exercise are beneficial for DM patients.

Methods: A comprehensive literature review was conducted using the PubMed and Google Scholar databases, focusing on articles published between 2018 and 2024.

State of Knowledge: The review identified consistent evidence supporting the safety and efficacy of exercise in DM patients. Exercise regimens, including resistance, aerobic, and stretching exercises, were found to improve muscle strength, aerobic capacity, and metabolic functions without increasing disease activity. Novel exercise approaches, such as blood flow restriction training and aquatic plyometric exercises, also showed promising results. However, the heterogeneity of the trials and small sample sizes highlight the need for larger, more diverse cohorts and long-term studies

Summary: The findings underscore the potential of structured exercise programs to enhance muscle strength, aerobic capacity, and overall physical function in DM patients. These improvements are achieved without exacerbating disease activity, highlighting the safety of exercise interventions. The review emphasizes the importance of incorporating physical activity into treatment plans for DM, advocating for personalized exercise prescriptions tailored to the unique inflammatory nature of idiopathic inflammatory myopathies (IIM).