The increased body mass index effect on declarative memory

Authors

  • Blanka Dwojaczny Department of Human Physiology, Nicolaus Copernicus University, Collegium Medicum Bydgoszcz
  • Tomasz Zegarski Centre for Physical Education and Sport, Nicolaus Copernicus University, Collegium Medicum Bydgoszcz
  • Wojciech Sikorski Department of Human Physiology, Nicolaus Copernicus University, Collegium Medicum Bydgoszcz
  • Piotr Złomańczuk Department of Neuroimmunology, Nicolaus Copernicus University, Collegium Medicum Bydgoszcz
  • Małgorzata Tafil-Klawe Department of Human Physiology, Nicolaus Copernicus University, Collegium Medicum Bydgoszcz

DOI:

https://doi.org/10.12775/MBS.2016.011

Keywords

face/name association, memory, body weight, BMI

Abstract

Several lines of evidence suggest that being overweight or obese not only impacts the cardiovascular and respiratory systems but also exert a negative effect on the central nervous system. We examined the relationship between body mass index and cognitive performance in three groups of volunteers: obese (17 women; aged 59.88 ± 4.29; BMI 34.08 ± 2.31), overweight (35 women; aged 59.70 ± 4.68; BMI 27.87± 1.44), and normal body weight group (18 women; aged 64.5 ±4.84; BMI 23.53 ± 1.21). To evaluate the cognitive performance in our subjects we used face/name association test. Our data demonstrate that the increased body mass weight may have a negative effect on some cognitive function such as declarative memory.

References

Kopelman PG. Obesity as a medical problem. Nature 2000; 404: 635-643.

Hart DJ, Spector TD. The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Reumatol 1993; 20: 331–5.

Haslam DW, James WP. Obesity. Lancet 2005;366:1197-1209.

Hannestad YS, Rortveit D, Deltveit AK et al. Are smoking and other lifestyle factors associated with female urinary incontinence? BJOG 2003;110:247-254.

Jensen GL, Friedmann JM. Obesity is associated with functional decline in community-dwelling rural older persons. J Am Geriatr Soc 2002; 50:918-923.

Bergstrom A, Pisani P, Tenet V et al. Overweight as an avoidable cause of cancer in Europe. Int J Cancer 2001; 91: 421–30.

Boeka AG, Lokken KL. Neuropsychological performance of a clinic sample of extremely obese inviduals. Arch Clin Neuropsychol 2008; 23:467-474.

Gunstad J, Paul RH,Cohen RA et al. Elevated body mass index is associated with executive dysfunction in otherwise healthy adults. Compr Psychiatry 2007; 48:57-61.

Elias MF, Elias PK, Sullivan LM et al. Lover cognitive function in the presence of obesity and hypertension. Int J Obes Relat Metab Disord 2003;27:260-268.

Cournot M, Marquie JC, Ansiau D et al. Relation between body mass index and cognitive function in healthy middle-aged men and women . Neurology 2006; 67:1208-1214.

Sabia S, Kivimaki M, Shipley MJ et al. Body mass index over the adult life course and cognition in late midlife: the Whitehall II Cohort Study. AM J Clin Nutr 2009;89:601-607.

Stanek KM, Strain G, Devlin M et al. Body mass index and neurocognitive functioning across the adult lifespan. Neuropsychology 2013;27:141-151.

Whitmer RA, Gunderson EP, Barrett-Connor E. Obesity in middle age and future risk of dementia. A 27 year longitudinal population based study. BMJ 2005; 330-1360.

Gustafson.D, Rothenberg E, Blennow K et al. An 18-year follow-up of body mass index and risk for Alzhaimer’s disease. Arch Intern Med 2003; 163:1524-1528.

Gustafson D. Adiposity indices and dementia. Lancet Neurol 2006; 5:713-720.

Enzinger C, Fazekas F, Matthews PM et al. Risk factors for progression of brain atrophyin aging: six-year follow-up of normal subject. Neurology2005;64:1704-1711.

Ward MA, Carlsson CM, Trivedi MA et al. The effect of body mass index on global brain volume in middle-aged adults. A cross sectional study. BMC Neurol 2005; 5:23.

Taki Y, Kinomura S, Sato K et al. Relationship between body mass index and gray metter volume in 1,428 health inviduals. Obesity 2008; 16: 119-124.

Gustafson D, Lissner L, Bengtsson C et al. A 24-year follow-up of body mass index and cerebral atrophy. Neurology 2004;63: 1876-1881.

Molteni R, Barnard RJ, Ying Z et al. A high-fat refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity and learning. Neuroscience 2002;112:803-804.

Wu A, Molteni R, Ying Z et al. A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain derived neurotrophic factor. Neuroscience 2003;119:365-375.

Moraes JC, Coope A, Morari J et al. High-fat diet induces apoptosis of hypothalamic neurons. PloS One 2009;4:5045-5056.

Volkov ND, Wang GJ, Telang F et al. Inverse association between BMI and prefrontal metabolic activity in healthy adults. Obesity 2009; 17:60-65.

Harvey J. Leptin regulation of neuronal excitability and cognitive function. Curr Opin Pharmacol 2007; 7:643-647.

Gunstand J, Spitznagel MB, Keary TA et al. Serum leptin levels are associated with cognitive function in older adults. Brain Res 2008;1230:233-236.

Sriram K, Benkovic SA, Miller DB et al. Obesity exacerbates chemically induced neurodegeneration. Neuroscience 2002;115:1335-1346.

Gorelick PB. Role of inflammation in cognitive impairment: result of observational epidemiological studies and clinical trials. Ann NY Acad Sci2010;1207:155-1562.

Obesity Education Initiative: The Evidence Report. Bethesda, MD: National Heart Lung and Blood Institute, National Institutes of Health, 1998.

Złomańczuk P, Milczarek B, Dmitruk K et al. Improvement in the face/name association performance after three months of physical training in elderly women. J Physiol Pharmacol 2006;57: 417-424.

Elias MF, Elias PK, Sullivan LM et al. Obesity, diabetes and cognitive deficit: the Framingham Heart Study. Neurobiol 2005;26:11-16.

Gunstad J, Paul RH, Cohen RA et al. Obesity is associated with memory deficits in young and middle-aged adults. Fat Weight Disord 2006;11:9-15.

Jurdak N, Lichtenstein AH, Kanarek RB. Diet-induced obesity and spatial cognition in young male rats. Nutr Neurosci 2008;11:48-54.

Granholm AC, Bimonte-Nelson HA, Moore AB et al. Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat. J Alzheimers Dis 2008;14:133-145.

Kanoski SE, Davidson TL. Different patterns of memory impairments accompany short and longer –term maintenance on a high –energy diet. J Exp Psychol Anim Behav Process 2010;36:313-319.

Sweat V, Starr V, Bruehl H et al. C-reactive protein is linked to lower cognitive performance in overweight and obese women. Inflammation 2008;31:198-207.

Ward MA, Carlsson CM, Trivedi MA et al. The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study. BMC Neurol 2005;2:5-23.

Kuo HK, Jones RN, Milberg WP et al. Cognitive function in normal-weight, overweight and obese older adults: an analysis of the Advanced Cognitive Training for Independent and Vital Elderly cohort. J Am Geriatr 2006;54:97-103.

Goodman-Gruen D, Barrett-Connor E. Sex differences in body fat and body fat distribution in the elderly .Am J Epidemiol 1996;143:898-906.

Medical and Biological Sciences

Downloads

Published

2016-06-15

How to Cite

1.
DWOJACZNY, Blanka, ZEGARSKI, Tomasz, SIKORSKI, Wojciech, ZŁOMAŃCZUK, Piotr and TAFIL-KLAWE, Małgorzata. The increased body mass index effect on declarative memory. Medical and Biological Sciences. Online. 15 June 2016. Vol. 30, no. 2, pp. 13-18. [Accessed 3 March 2026]. DOI 10.12775/MBS.2016.011.

Issue

Vol. 30 No. 2 (2016)

Section

ORIGINAL ARTICLES

Stats

Number of views and downloads: 477
Number of citations: 0