Case report of a Patient with SVC syndrome in the course of pulmonary hilar and mediastinal neoplasia
DOI:
https://doi.org/10.12775/QS.2025.40.59557Keywords
superior vena cava, SVC, SVC syndrome, pulmonary neoplasm, venous thrombosis, case report, mediastinal tumourAbstract
Superior vena cava syndrome (SVCS) is a serious clinical condition caused by obstruction of the superior vena cava, usually due to malignancies. We present a case of a 67-year-old woman with SVCS secondary to a tumour in the right pulmonary hilum and mediastinum. The patient exhibited facial and neck swelling, venous distention, and dyspnoea. Computed tomography confirmed a large polycystic mass causing complete occlusion of the superior vena cava and extensive venous thrombosis. The patient was treated with anticoagulation therapy and referred for oncological assessment. This case underscores the importance of prompt diagnosis and imaging in guiding SVCS management.
References
[1] Chitwood WR Jr. John and William Hunter on aneurysms. Arch Surg. 1977 Jul;112(7):829-36. doi:10.1001/archsurg.1977.01370070043005. PMID: 327974.
[2] Klein-Weigel PF, Elitok S, Ruttloff A, Reinhold S, Nielitz J, Steindl J, Hillner B, Rehmenklau-Bremer L, Wrase C, Fuchs H, Herold T, Beyer L. Superior vena cava syndrome. Vasa. 2020 Oct;49(6):437- 448. doi: 10.1024/0301-1526/a000908. PMID: 33103626.
[3] Aleksandra Kotlińska-Lemieszek, Wojciech M. Wysocki, Zespół żyły głównej górnej, Medycyna Praktyczna, 2021 Aug, https://www.mp.pl/interna/chapter/B16.II.2.32.
[4] Patriarcheas V, Grammoustianou M, Ptohis N, Thanou I, Kostis M, Gkiozos I, Charpidou A, Trontzas I, Syrigos N, Kotteas E, Dimakakos E. Malignant Superior Vena Cava Syndrome: State of the Art. Cureus. 2022 Jan 4;14(1):e20924. doi: 10.7759/cureus.20924. PMID: 35004083; PMCID: PMC8727327
[5] Talapatra K, Panda S, Goyle S, Bhadra K, Mistry R. Superior vena cava syndrome: A radiation oncologist's perspective. J Cancer Res Ther. 2016 Apr-Jun;12(2):515-9. doi: 10.4103/0973- 1482.177503. PMID: 27461602.
[6] Armstrong BA, Perez CA, Simpson JR, Hederman MA. Role of irradiation in the management of superior vena cava syndrome. Int J Radiat Oncol Biol Phys. 1987 Apr;13(4):531-9. doi: 10.1016/0360- 3016(87)90068-x. PMID: 3558044.
[7] Yu JB, Wilson LD, Detterbeck FC. Superior vena cava syndrome--a proposed classification system and algorithm for management. J Thorac Oncol. 2008 Aug;3(8):811-4. doi:
10.1097/JTO.0b013e3181804791. PMID: 18670297.
[8] Kopanczyk, R, Al-Qudsi OH, Ganapathi AM, Potere BR, Pagel PS. Superior vena cava syndrome during veno-venous extracorporeal membrane oxygenation for COVID-19. Perfusion. 2021 Sep;36(6):630-633. doi: 10.1177/0267659120987973. Epub 2021 Jan 9. PMID: 33427042.
[9] Arora Y, Carrillo RG. Lead-related superior vena cava syndrome: Management and outcomes. Heart Rhythm. 2021 Feb;18(2):207-214. doi: 10.1016/j.hrthm.2020.09.006. Epub 2020 Sep 11. PMID: 32920177.
[10] Chan RC, Chan YC, Cheng SW. Mid- and long-term follow-up experience in patients with malignant superior vena cava obstruction. Interact Cardiovasc Thorac Surg. 2013 Apr;16(4):455-8. doi: 10.1093/icvts/ivs562. Epub 2013 Jan 10. PMID: 23307930; PMCID: PMC3598049.
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