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Quality in Sport

Influence of pulmonary sequestration on growth and body weight: Case report and literature review
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  • Influence of pulmonary sequestration on growth and body weight: Case report and literature review
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Influence of pulmonary sequestration on growth and body weight: Case report and literature review

Authors

  • Joanna Rypel-Bośka Podhalański Szpital Specjalistyczny im. Jana Pawła II w Nowym Targu https://orcid.org/0009-0002-2380-571X
  • Natalia Siuta Podhale Specialist Hospital of John Paul II in Nowy Targ, Poland https://orcid.org/0000-0001-8441-5382
  • Kamil Ciechomski University Clinical Hospital No. 1 named after Norbert Barlicki, Łódź, Poland https://orcid.org/0009-0002-0049-2714
  • Izabela Brynczka Poznań University of Medical Sciences, Poznań, Poland https://orcid.org/0009-0002-1527-5659
  • Marcin Migiel Podhale Specialist Hospital of John Paul II in Nowy Targ, Poland https://orcid.org/0009-0003-3562-5051
  • Jakub Miaśnikiewicz Central Teaching Hospital of the Medical University of Lodz, Poland https://orcid.org/0009-0003-3186-010X
  • Klaudia Goleniowska University Clinical Hospital No. 2 of Medical University of Łódź, Poland https://orcid.org/0009-0002-1597-9699
  • Aleksandra Gieras University Clinical Hospital No. 1 named after Norbert Barlicki, Łódź, Poland https://orcid.org/0009-0004-3585-9664
  • Elżbieta Siuda University Clinical Hospital No. 1 named after Norbert Barlicki, Łódź, Poland https://orcid.org/0009-0004-9178-9138
  • Wiktoria Cecuła Medical University of Lodz, Łódź, Poland https://orcid.org/0009-0005-8749-2312

DOI:

https://doi.org/10.12775/QS.2025.42.61001

Keywords

pulmonary sequestration, thoracotomy, congenital lung anomalies, growth, body weight

Abstract

Background: Pulmonary sequestration is a rare congenital anomaly involving non-functional lung tissue with systemic arterial blood supply. Its implications for pediatric growth and weight are poorly documented.

Case report: An 8-years-and-10-month-old previously healthy boy was diagnosed with pulmonary sequestration following pneumonia. Chest imaging revealed emphysematous changes, and computed tomography confirmed intralobar sequestration. Surgical removal was performed, revealing significant growth impairment with weight (18.9 kg) and height (117 cm), both below the 3rd percentile at admission, despite normal laboratory findings.

Discussion: Pulmonary sequestration can negatively influence pediatric growth due to chronic inflammation and hypoxia from recurrent infection. Surgical intervention typically results in clinical improvement and significant catch-up growth.

Conclusion: This case highlights pulmonary sequestration’s potential negative impact on pediatric growth and underscores the importance of early surgical intervention for improving growth outcomes.

References

Savic, B., Birtel, F. J., Tholen, W., Funke, H. D., & Knoche, R. (1979). Lung sequestration: report of seven cases and review of 540 published cases. Thorax, 34(1), 96–101.

Bratu, I., Flageole, H., Chen, M. F., Di Lorenzo, M., Yazbeck, S., & Laberge, J. M. (2005). The multiple facets of pulmonary sequestration. Journal of Pediatric Surgery, 40(5), 784–790.

Sun, X., & Xiao, Y. (2012). Pulmonary sequestration in children: a clinical analysis of 48 cases. Journal of Pediatric Surgery, 47(12), 2244–2248.

Lee, E. Y., Boiselle, P. M., & Cleveland, R. H. (2008). Multidetector CT evaluation of congenital lung anomalies. Radiology, 247(3), 632–648.

Wang, H., Duan, L., Zhong, L., Zhong, W., & Wang, Q. (2015). Pulmonary sequestration: A retrospective analysis of 2625 cases in China. Pediatrics and Neonatology, 56(1), 45–49.

Riedlinger, W. F., Vargas, S. O., Jennings, R. W., et al. (2011). Embryologic basis of pulmonary sequestration: A histopathologic and immunohistochemical study. Pediatric and Developmental Pathology, 14(6), 427–432.

Hardy, O. T., Czech, M. P., & Corvera, S. (2012). What causes the insulin resistance underlying obesity? Current Opinion in Endocrinology, Diabetes and Obesity, 19(2), 81–87.

Wit, J. M., Oostdijk, W., Losekoot, M., van Duyvenvoorde, H. A., & van Schaik, R. H. N. (2016). Mechanisms in endocrinology: Novel genetic causes of short stature. Hormone Research in Paediatrics, 86(6), 361–377.

Gozal, D., & Kheirandish-Gozal, L. (2006). Obstructive sleep apnea and inflammation: proof of concept based on two illustrative cytokines. Chest, 130(6), 1913–1919.

Gore, D. C., Honeycutt, D., Jahoor, F., Barrow, R. E., Wolfe, R. R., & Herndon, D. N. (2008). Propranolol diminishes extremity blood flow in severely burned patients. Journal of Burn Care & Research, 29(2), 288–292.

Marcinow, A., Wroński, J., Barczuk-Falęcka, M., et al. (1998). Pulmonary sequestration: A comparison between pediatric and adult patients. European Journal of Cardio-Thoracic Surgery, 19(4), 388–395.

Matsubara, Y., et al. (2023). Sublobar resection utilizing near-infrared thoracoscopy with intravenous indocyanine green for intralobar pulmonary sequestration: a case report and literature review. Surgical Case Reports, 9(1), 176.

Corbett, H. J., Dickinson, R. J., & Hindle, D. (2022). Modern surgical approaches to pulmonary sequestration: A systematic review. Annals of Pediatric Surgery, 18(1), 24.

Tong, Z., et al. (2023). Pulmonary sequestration in adult patients: a single-center retrospective study. Respiratory Research, 24(1), 13.

Molinari, J. V., et al. (2023). Case report: Pulmonary sequestration with gastric fistula in a 20-year-old woman. Seven Editora.

Quality in Sport

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Published

2025-06-24

How to Cite

1.
RYPEL-BOŚKA, Joanna, SIUTA, Natalia, CIECHOMSKI, Kamil, BRYNCZKA, Izabela, MIGIEL, Marcin, MIAŚNIKIEWICZ, Jakub, GOLENIOWSKA, Klaudia, GIERAS, Aleksandra, SIUDA, Elżbieta and CECUŁA, Wiktoria. Influence of pulmonary sequestration on growth and body weight: Case report and literature review. Quality in Sport. Online. 24 June 2025. Vol. 42, p. 61001. [Accessed 29 June 2025]. DOI 10.12775/QS.2025.42.61001.
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Vol. 42 (2025)

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Medical Sciences

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Copyright (c) 2025 Joanna Rypel-Bośka, Natalia Siuta, Kamil Ciechomski, Izabela Brynczka, Marcin Migiel, Jakub Miaśnikiewicz, Klaudia Goleniowska, Aleksandra Gieras, Elżbieta Siuda, Wiktoria Cecuła

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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