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Quality in Sport

The Hyperandrogenism in Female Athletes: When Dermatological Signs Become an Endocrine and Sports Medicine Challenge
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The Hyperandrogenism in Female Athletes: When Dermatological Signs Become an Endocrine and Sports Medicine Challenge

Authors

  • Damian Stencelewski University Clinical Centre, Gdańsk, Poland https://orcid.org/0009-0002-7359-5562
  • Jakub Pawlicki St. Wojciech Hospital, Jana Pawła II Avenue, 80-462 Gdańsk, Poland https://orcid.org/0009-0007-3888-4672
  • Aleksandra Gorzynska-Schulz Medical University of Gdańsk, Poland https://orcid.org/0009-0005-1719-8548
  • Natalia Gorzynska Pomeranian Medical University, Szczecin, Poland https://orcid.org/0009-0007-3891-9636
  • Michał Falis University Clinical Centre, Gdańsk, Poland https://orcid.org/0009-0002-1074-6036
  • Alicja Nierychlewska https://orcid.org/0009-0009-6783-4601
  • Agata Bronisławska St. Wojciech Hospital, Jana Pawła II Avenue, 80-462 Gdańsk, Poland https://orcid.org/0009-0003-3833-0638
  • Robert Bronisławski St. Wojciech Hospital, Jana Pawła II Avenue, 80-462 Gdańsk, Poland https://orcid.org/0009-0004-6494-4307
  • Alicja Solecka University Clinical Centre, Gdańsk, Poland https://orcid.org/0009-0001-0688-309X
  • Lidia Kiełbratowska Pomeranian Medical University, Szczecin, Poland https://orcid.org/0009-0000-6322-7446

DOI:

https://doi.org/10.12775/QS.2026.73.75440

Keywords

'Hyperandrogenism', female athletes, Hirsutism, Relative energy deficiency in sport

Abstract

Background. Hyperandrogenism in female athletes represents a complex intersection of endocrinology, dermatology, and sports medicine, where visible dermatological markers often signal underlying endocrine dysfunction or exogenous exposure.

Aim. This narrative review analyzes the pathophysiology, differential diagnosis, and clinical management of hyperandrogenism in female athletes, distinguishing between endogenous endocrine disorders, exercise-induced adaptations, and performance-enhancing drug use.

Material and methods. A literature search of PubMed and Google Scholar was conducted to identify recent clinical guidelines, endocrinological studies, and sports medicine literature regarding female hyperandrogenism, dermatological manifestations, and RED-S.

Results. Dermatological signs such as severe acne, hirsutism, and female pattern hair loss serve as critical clinical red flags. Differentiating pathological conditions like Polycystic Ovary Syndrome (PCOS) from Relative Energy Deficiency in Sport (RED-S) and exogenous androgen exposure is essential for accurate diagnosis and regulatory compliance in sports medicine.

Conclusions. Effective management of hyperandrogenism in female athletes requires a multidisciplinary approach, combining dermatological evaluation, rigorous endocrine profiling, and sports medicine oversight to safeguard both athletic health and long-term well-being.

References

1. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. https://doi.org/10.1093/ageing/afy169

2. Hirschberg AL. Female hyperandrogenism and elite sport. J Clin Endocrinol Metab. 2020;105(3):dgaa068. https://doi.org/10.1210/clinem/dgaa068

3. Mountjoy M, Sundgot-Borgen J, Burke L, Ackerman KE, Blauwet C, Constantini N, et al. IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. Br J Sports Med. 2018;52(11):687-697. https://doi.org/10.1136/bjsports-2018-099196

4. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, et al. International evidence-based guideline for the assessment and management of polycystic ovary syndrome 2018. Fertil Steril. 2018;110(3):364-380. https://doi.org/10.1016/j.fertnstert.2018.06.002

5. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2013;98(12):4565-4592. https://doi.org/10.1210/jc.2013-2350

6. Ackerman KE, Holtzman B, Cooper AB, Flynn EF, Bruinvels G, Tenforde AS, et al. Low energy availability surrogates correlate with health and performance consequences of Relative Energy Deficiency in Sport. Sports Med. 2019;49(1):1-12. https://doi.org/10.1007/s40279-018-0995-8

7. De Souza MJ, Nattiv A, Joy E, Misso M, Williams NI, Mallinson RJ, et al. 2014 Female Athlete Triad Coalition consensus statement on treatment and return to play of the female athlete triad. Br J Sports Med. 2014;48(4):289. https://doi.org/10.1136/bjsports-2013-093218

8. Hirschberg AL. Female Hyperandrogenism in Elite Sports and the Athletic Triad. Semin Reprod Med. 2022;40(1-2):32-41. https://doi.org/10.1055/s-0041-1736337

9. Bermon S, Garnier PY, Hirschberg AL, Robinson N, Giraud S, Piccoli LJ, et al. Serum androgen levels and their relation to performance in elite female athletes: a cross-sectional study. Br J Sports Med. 2014;48(1):130-135. https://doi.org/10.1136/bjsports-2013-092843

10. Speiser PW, Arlt W, Auchus RJ, Baskin LS, Conway GS, Merke DP, et al. Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(11):4043-4088. https://doi.org/10.1210/jc.2018-01865

11. Auchus RJ, Arlt W. Approach to the patient: the congenital adrenal hyperplasias due to 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2013;98(3):901-907. https://doi.org/10.1210/jc.2012-2661

12. Futterman R, Handelsman DJ. Androgens and athletic performance in women. Curr Opin Endocrinol Diabetes Obes. 2016;23(3):236-241. https://doi.org/10.1097/MED.0000000000000250

13. Handelsman DJ, Hirschberg AL, Bermon S. Circulating testosterone as the hormonal basis of sex differences in athletic performance. Endocr Rev. 2018;39(5):803-829. https://doi.org/10.1210/er.2018-00020

14. Gleeson M. Immune function in sport and exercise. J Appl Physiol (1985). 2007;103(2):693-699. https://doi.org/10.1152/japplphysiol.00008.2007

15. Hackney AC. Stress and the neuroendocrine system: the relationship with physical exercise. Expert Rev Endocrinol Metab. 2006;1(6):783-792. https://doi.org/10.1586/17446651.1.6.783

16. Melin AK, Tornberg ÅB, Skolnick S, Faber J, Sjödin A. The LEAF questionnaire: a screening tool for the identification of female athletes at risk for the female athlete triad. Br J Sports Med. 2014;48(7):540-545. https://doi.org/10.1136/bjsports-2013-093240

17. Loucks AB, Kiens B, Wright HH. Energy availability in athletes. J Sports Sci. 2011;29(sup1):S7-S15. https://doi.org/10.1080/02640414.2011.588958

18. Hagmar M, Berglund L, Brismar K, Hirschberg AL. Body composition and endocrine profile in male and female distance runners. Scand J Med Sci Sports. 2013;23(4):e197-e204. https://doi.org/10.1111/sms.12047

19. Nattiv A, Loucks AB, Manore MM, Sanborn CF, Sundgot-Borgen J, Warren MP. American College of Sports Medicine position stand. The female athlete triad. Med Sci Sports Exerc. 2007;39(10):1867-1882. https://doi.org/10.1249/mss.0b013e318149f111

20. Gordon CM, Ackerman KE, Berga SL, Kaplan JR, Mastorakos G, Misra M, et al. Functional hypothalamic amenorrhea: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2017;102(5):1413-1439. https://doi.org/10.1210/jc.2017-00131

21. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009;91(2):456-488. https://doi.org/10.1016/j.fertnstert.2008.06.035

22. Carmina E, Stanczyk FZ, Lobo RA. The diagnosis of polycystic ovary syndrome: is it time to change the criteria? Nat Rev Endocrinol. 2010;6(10):580-584. https://doi.org/10.1038/nrendo.2010.127

23. Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: aetiology, pathogenesis and diagnosis. Nat Rev Endocrinol. 2011;7(4):219-231. https://doi.org/10.1038/nrendo.2010.217

24. Escobar-Morreale HF. Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nat Rev Endocrinol. 2018;14(5):270-284. https://doi.org/10.1038/nrendo.2018.24

25. Sattar N, Preiss D. The metabolic syndrome: practical concepts and scientific challenges. BMJ. 2012;344:e469. https://doi.org/10.1136/bmj.e469

26. Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, et al. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and PCOS Society and the American Society for Reproductive Medicine. Fertil Steril. 2010;94(6):1986-1993. https://doi.org/10.1016/j.fertnstert.2010.04.053

27. World Anti-Doping Agency (WADA). The World Anti-Doping Code: International Standard Prohibited List 2026. Montreal: WADA; 2026.

28. Mottram DR, Chester N, editors. Drugs in Sport. 7th ed. London: Routledge; 2022.

29. Sonksen PH, Holt RI. Sarcopenia: revised European consensus on definition and diagnosis. Br J Sports Med. 2015;49(1):12-13. https://doi.org/10.1136/bjsports-2014-094459

30. Thompson B, Mauger AR, Warren A. Mental health and body image in elite female athletes: psychosocial considerations. Sports Med Open. 2021;7(1):45. https://doi.org/10.1186/s40798-021-00334-y

Quality in Sport

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Published

2026-09-23

How to Cite

1.
STENCELEWSKI, Damian, PAWLICKI, Jakub, GORZYNSKA-SCHULZ, Aleksandra, GORZYNSKA, Natalia, FALIS, Michał, NIERYCHLEWSKA, Alicja, BRONISŁAWSKA, Agata, BRONISŁAWSKI, Robert, SOLECKA, Alicja and KIEŁBRATOWSKA, Lidia. The Hyperandrogenism in Female Athletes: When Dermatological Signs Become an Endocrine and Sports Medicine Challenge. Quality in Sport. Online. 23 September 2026. Vol. 76, p. 75440. [Accessed 25 September 2026]. DOI 10.12775/QS.2026.73.75440.
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Vol. 76 (2026)

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Copyright (c) 2026 Damian Stencelewski, Jakub Pawlicki, Aleksandra Gorzynska-Schulz, Natalia Gorzynska, Michał Falis, Alicja Nierychlewska, Agata Bronisławska, Robert Bronisławski, Alicja Solecka, Lidia Kiełbratowska

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